Genomic characterization of Enterobacter hormaechei subsp. xiangfangensis isolated from a urinary tract infection: insights into antibiotic resistance determinant and mobile genetic elements

#WholeGenomeSequencing of Enterobacter hormaechei from a #UTI case in Côte d’Ivoire reveals #MultiDrugResistance, plasmid-mediated elements, and ST114 lineage, underscoring genomic surveillance for better AMR diagnostics in resource-limited settings.

Read: doi.org/10.1016/j.dc...

WHO report signals tuberculosis resurgence: Addressing systemic failures and revamping control strategies

An overview of the #Epidemiology of #Tuberculosis resurgence—driven by #COVID19, #MultidrugResistance, and socioeconomic shifts—highlighting the need for revamped control strategies, sustainable research funding, and digital surveillance. #MedSky

#OpenAccess: doi.org/10.1016/j.dc...

KSQ‐4279, an Inhibitor of Ubiquitin Specific Peptidase 1, Enhanced the Chemotherapeutic Efficacy in ABCB1/ABCG2/ABCC1‐Mediated Multidrug Resistant Cancers KSQ-4279, an USP1 inhibitor in clinical trial, widely reversed multidrug resistance in refractory cancers by competing for the drug-binding pockets of ABCB1/ABCG2/ABCC1 and blocking chemotherapeutic ...

#Article in #MedComm
KSQ-4279, an Inhibitor of Ubiquitin Specific Peptidase 1, Enhanced the Chemotherapeutic Efficacy in ABCB1/ABCG2/ABCC1-Mediated Multidrug Resistant Cancers doi.org/10.1002/mco2...

#MultidrugResistance #MDR #USP1 #ABC #KSQ4279 #CombinationChemotherapy

Antimicrobial resistance risks from bacteria in 'Trojan horse' amoebae Amoebae living in a creek in Mumbai are acting as a "Trojan horse," harboring and protecting multidrug resistant bacteria, according to new research.

#Antimicrobial resistance risks from #bacteria in 'Trojan horse' #amoebae ...

| #AMR | #microbes | #multidrugresistance | #infections | By @unistrathclyde.bsky.social via @sciencex.bsky.social

Mapping 100 years of antibiotic resistance evolution to pinpoint the genetic culprits The genetic culprits responsible for the spread of multidrug resistance (MDR) in bacteria have been identified by new research mapping 100 years of bacterial evolution.

Mapping 100 years of #antibiotic resistance #evolution ...

| #antibioticresistance | #multidrugresistance | #bacteria | #AMR | Via @sciencex.bsky.social

Scientists discover powerful new antibiotic class to tackle deadly superbugs Scientists at the University of Liverpool, working with international collaborators, have discovered Novltex, a groundbreaking new class of antibiotics with potent activity against some of the…

Powerful new #antibiotic class to tackle deadly #superbugs ...

| #bacteria | #multidrugresistance | #AMR | #antimicrobialresistance | By @liverpooluni.bsky.social via @sciencex.bsky.social

The hospital sink drain microbiome as a melting pot for AMR transmission to nosocomial pathogens - npj Antimicrobials and Resistance npj Antimicrobials and Resistance - The hospital sink drain microbiome as a melting pot for AMR transmission to nosocomial pathogens

The #hospital #sink drain #microbiome as a melting pot for #AMR transmission to #nosocomial #pathogens ...

| #antibiotics | #antimicrobialresistance | #drugs | #multidrugresistance | #microbes | Via @nature.com

In vitro susceptibility of aztreonam/avibactam against metallo-β-Lactamase-producing Enterobacterales in a Croatian tertiary care hospital

[Publication] The article "In vitro susceptibility of aztreonam/avibactam against metallo-β-Lactamase-producing Enterobacterales in a Croatian tertiary care hospital" is now available.

www.sciencedirect.com/science/arti...

#IDsky #AntimicrobialTreatment #Enterobacterales #MultidrugResistance

🎉
#MDRRA has launched! 🚀
We’re tackling #MultiDrugResistance in difficult-to-treat #RA with cutting-edge #research & #AI tools. Follow us for updates, insights & breakthroughs!🌟Kick-off Meeting: Jan 21-22, 2025. Stay tuned!

www.linkedin.com/company/mdr-...

#MDRRAProject #HorizonEU #Rheumatology💊✨

Melatonin-induced methylation of the ABCG2/BCRP promoter as a novel mechanism to overcome multidrug resistance in brain tumour...

#Melatonin #Cancer #StemCells #brain #tumour #methylation #genetic #promoter #multidrugresistance #IUOPA

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