Key Points • First-line therapies for functional dyspepsia, including proton pump inhibitors and Helicobacter pylori eradication, provide limited symptom relief in a substantial proportion of patients. • Functional dyspepsia and gastroparesis share overlapping symptoms but differ in predominant pathophysiological mechanisms, requiring tailored therapeutic strategies. • Predominantly central neuromodulators are most appropriate for epigastric pain syndrome, whereas predominantly peripheral neuromodulators are better suited for postprandial distress syndrome and gastroparesis-related nausea and vomiting. • A pragmatic, symptom-oriented, and mechanism-based approach may facilitate individualized treatment selection and optimize clinical outcomes.
🆕🔥Central & peripheral #Neuromodulators in #FD & #Gastroparesis: Symptom-Based #ClinicalReview‼️
🎯A pragmatic, symptom-oriented & mechanism-based approach facilitate individualized treatment selection & optimize clinical outcomes
👉 onlinelibrary.wiley.com/doi/10.1111/...
#ANMS #ESNM
