In this work, we characterized the third Ig domain of human MuSK, a #cellsurface #receptor #protein #kinase critical for #neuromuscularjunction formation and stabilization.

Myasthenia Gravis: Autoimmune Neuromuscular Disorder, Symptoms, Diagnosis & Crisis Management
#MyastheniaGravis #Neurology #AutoimmuneDisease #VikaasShandily #NeuromuscularJunction

From our latest issue 🆕 research from @uottawa.bsky.social demonstrating peripheral effects before motor neuron loss in the #SMA 2B/- mouse model. Read the #openaccess paper here: buff.ly/51H530o #spinalmuscularatrophy #neuromuscularjunction

I am loving our chemistry... 🧪🧠🔬
#FlourescentFriday #fluorescenceFriday #iykyk #neuromuscularjunction #ALS #science #synapse #chemistry #happyfriday

#hiPSC #Senorimotor #Organoid
->Neural/Microglia/Vessel/Striated myofiber
->Modeling the impacts of #AmyotrophicLateralSclerosis variants (TDP43/SOD1/PFN1) on #NeuroMuscularJunction

To study Pericyte-NMJ crosstalk?

Brian Wainger lab #NatureComms 2021
www.nature.com/articles/s41...