With biotech, is it the destination, the journey, or both?

Find out on the @biorasi.bsky.social Few & Far Between podcast, with guest Amit Etkin, Founder and CEO #altoneuro.

Watch it today on our YouTube channel >> youtu.be/Dl3QJUCGstA

#schizophrenia #biotech #placebos #biomarkers #psychiatry

How do we know if we're using the right method to calculate #carboncredits generated by forest-saving #REDD+ projects? Test the method on #placebos! New paper out in Environmental Research Letters : https://doi.org/10.1088/1748-9326/ae0f44 #naturebasedsolutions #emissionsreductions #netzero

How do we know if we're using the right method to calculate #carboncredits generated by forest-saving #REDD+ projects? Test the method on #placebos! New paper out in Environmental Research Letters : doi.org/10.1088/1748-9326/ae0f44 #naturebasedsolutions

To the left, Julia is tucked up in bed feeling sick. To the right she is sitting up smiling with a tray of medicine and feel good foods. Text: My hypochondria's so bad my doctor prescribes me broad spectrum placebos.

My #hypochondria's so bad my doctor prescribes me broad spectrum #placebos.

Kann der Placeboeffekt Kindern beim Abnehmen helfen? Der Placeboeffekt funktioniert auch dann, wenn transparent ist, dass ein Mittel keinen Wirkstoff enthält. Ein Grazer Forschungsteam untersucht diesen Ansatz nun als Intervention für Kinder mit Übergew...

Immer mehr Kinder und Jugendliche leben mit #Adipositas. Grazer Forschende erforschen einen neuen Ansatz, mit dem Kinder ihren Appetit besser regulieren können. Sie arbeiten mit offenen #Placebos als Intervention für Kinder mit Übergewicht. @uni-graz.at #scilog 💊

scilog.fwf.ac.at/magazin/kann...

Efficacy of open-label placebos for premenstrual syndrome: a randomised controlled trial Objective To investigate the efficacy and safety of open-label placebos (OLP) in premenstrual syndrome (PMS). Design Randomised controlled trial. Setting Switzerland, 2018–2020. Participants 150 women (18–45 years of age) with PMS or premenstrual dysphoric disorder. Intervention Random assignment (1:1:1) to treatment as usual (TAU), OLP without treatment rationale (OLP–), or OLP with treatment rationale (OLP+). OLP consisted of two placebo pills per day for 6 weeks. Main outcome measures Primary outcomes were PMS symptom intensity and interference between groups across three menstrual cycles (MC1–MC3); adverse events (ie, safety) were measured at weeks 3 and 6 after the start of the intervention. Secondary outcomes were psychological and somatic subscales of PMS symptom intensity, and adherence. Results From 2 August 2018 to 3 December 2020, 150 women were randomly allocated to TAU (n=50), OLP– (n=50), and OLP+ (n=50), of whom 145 (96.7%) completed trial participation. Groups differed in symptom intensity (F(4)=4.419, p=0.002, r2=0.16) and interference (F(4)=3.159, p=0.014, r2=0.13) across three MCs. Mean symptom intensity at MC3 was lower for OLP+ compared to TAU (b=–9.97, SE=2.85, t(412)=3.50, p<0.001, d=0.90) and to OLP– (b=–6.10, SE=2.89, t(411)=2.11, p=0.036, d=0.55), but OLP– and TAU did not differ (b=–3.87, SE=2.87, t(411)=1.35, p=0.177, d=0.35). Mean interference at MC3 was lower for OLP+ compared to TAU (b=–1.23, SE=0.54, t(443)=2.30, p=0.022, d=0.55) and to OLP– (b=–1.10, SE=0.54, t(442)=2.02, p=0.044, d=0.48), but OLP– and TAU did not differ (b=–0.14, SE=0.54, t(442)=0.26, p=0.799, d=0.06). Four non-serious adverse events were reported in OLP– (n=1) and OLP+ (n=3). Improvement in psychological and somatic symptom intensity was comparable to primary outcomes. Adherence to the OLP intervention was high (93.18±18.95%), with no difference between groups. Conclusions The results of our clinical trial indicate that OLP provided with a treatment rationale is an effective, safe, and acceptable treatment for PMS. Trial registration ClinicalTrials.gov [NCT03547661][1] (submitted 2 May 2018). Data are available in a public, open access repository. Meta-data is openly accessible on the data repository Harvard Dataverse. Upon reasonable request, relevant anonymised participant-level data will be made available. [1]: /lookup/external-ref?link_type=CLINTRIALGOV&access;_num=NCT03547661&atom;=%2Febmed%2Fearly%2F2025%2F03%2F05%2Fbmjebm-2024-112875.atom

Love this work! #Placebos more effective when patients aware. Would #rct double-blind protocols also have an impact? #MedSci
ebm.bmj.com/content/early/2025/03/05...

Studie: Mit offenen Placebos gegen PMS Von offenen Placebos spricht man, wenn Patienten wissen, dass es sich um eine Scheinbehandlung handelt. In einer Studie konnten offene Placebos Symptome de...

Von offenen #Placebos spricht man, wenn Patienten wissen, dass es sich um eine Scheinbehandlung handelt. In einer Studie konnten offene Placebos die Symptome bei Frauen mit #PMS um fast 80 Prozent reduzieren – jedoch nur wenn diese zuvor ausführlich über den Placeboeffekt aufgeklärt wurden.

Open-label placebos improve premenstrual syndrome Almost half of women of reproductive age experience complaints in the days leading up to menstruation. A lot of treatments come with side effects, only provide limited relief, or don’t work for everyo...

Almost half of women of reproductive age experience complaints in the days leading up to menstruation. Researchers from the University of Basel have shown that open-label #placebos can help, particularly when combined with an explanation of the treatment.

To the left, a comedian is tucked up in bed feeling sick. To the right she is sitting up smiling with a tray of medicine and feel good foods. Text: My hypochondria's so bad my doctor prescribes me broad spectrum placebos.

My #hypochondria is so bad my doctor prescribes me broad spectrum #placebos.

Guter Artikel von @anthroblogger.bsky.social ob #Homöopathie Tierquälerei ist.
Alle 9 der größten deutschen #Bio-Verbände befürworten oder akzeptieren, dass kranke (Nutz-)Tiere mit #Placebos „versorgt“ werden. Die Gabe von nachweislich wirkungsloser Scheinmedizin ist vorsätzliche Nicht-Behandlung.

Self Directed Learning, Placebos and Gambling. 07.01.25Happy New Year Readers! Bzzzz-bzzzz! Yara’s new phone jittered on the cracked tabletop like a panicked mosquito, shaking out a sticky-sweet tune in a boy’s thick Jamaican sing-song: “Mi want a hippopotamus fi Christmas…” The sound bounced off the peeling walls of the little, broken-down house, filling it with a strange kind of cheer. Malïa wrinkled her nose, her Bajan lilt as sharp as a broken Maltín Polar bottle.

For immediate release.

A post about Placebos, Gambling and Self-directed learning by Plakebo.

See the story and full discussion at the link below.

#Gambling #SOE #SelfDirectedLearning #Placebos

Dann sitze ich hier jetzt noch kurz und hoffe gleich auf das #Prüfpräparat statt des #Placebos 🤞🏻🙏🏻

To the left, a comedian is tucked up in bed feeling sick. To the right she is sitting up smiling with a tray of medicine and feel good foods. Text: My hypochondria's so bad my doctor prescribes me broad spectrum placebos.

My #hypochondria's so bad my doctor prescribes me broad spectrum #placebos.

Warum Medikamente ohne Wirkstoff heilen können und warum #Placebos sogar dann wirken, wenn man weiß, dass es „nur“ Placebos sind.
Wie immer wunderbar verständlich erklärt von den #QuarksScienceCops in ihrer Folge 65.

www.quarks.de/podcast/quar...

Tagging above tweet for those interested in:

#healthcare #science #scicomm #medical #experts #doctors #treatment #psuedoscience #naturalmedicine #placebos #holistic #unorthodox #unconventional #anecdotes #evidence #education #naturopath #learning #BeAware ✅

FYI @jonathanstea

There should be a secret range of #placebos GPs can call "#antibiotics". Then they can placate mardy patients and prescribe away.

#r4today

Fascinating history of #placebos - first referred to stand-in mourners; connotation of substitution, depreciation: www.ncbi.nlm.nih.gov/pmc/articles/PMC1297390/...