`"We discovered that it's due to the fact that there's an increase in a prostaglandin-degrading enzyme triggered by aging and injury. And we named this a gerozyme," the researcher said.
That gerozyme, also known as 15-PGDH, increases with age and drives the degeneration of tissue.` […]
Takaki Yahiro, Yoshiko Nakamura & Kazuhiro Nakamura from @en.nagoya-u.ac.jp
present a potential mechanism of chills, in that the pyrogenic mediator #prostaglandin E2 elicits warmth seeking via EP3 receptor-expressing parabrachial #neurons 🧠 🌡️
🔗 physoc.onlinelibrary.wiley.com/doi/10.1113/...
#Prostaglandin agonists produce an unexpected #analgesiceffect and prevent chronic postsurgical pain (#CPSP) in this #mousemodel
www.bjanaesthesia.org/article/S0007-0912(25)00...
#NSAID induced #Enteropathy: #Prostaglandin suppression plays only trivial role while enteropathic response to #NSAIDs might be amplified through #Dysbiosis of the #GutMicrobiome www.jci.org/articles/vie... @FitzGerald__Lab #TranslationalScience
In this paper, the #AsymmetricTotalSynthesis of tricyclic #prostaglandin D2 metabolite methyl ester via #OxidativeRadicalCyclization is shown. This synthesis improves clinical PGD2 monitoring and understanding its role in human health.
➡️ https://tinyurl.com/3mprh56e
#BJOC #DiamondOpenAccess 💎🔓
Structural insights into selective and dual antagonism of EP2 and EP4 #prostaglandin receptors
#CryoEM structures by H Eric Xu and colleagues reveal interactions of the dual antagonist TG6-129 with EP2 and EP4 via different pharmacophores
www.embopress.org/doi/full/10....
Deletion of EP3 #prostaglandin receptor in murine macrophages aggravates diet-induced obesity by suppressing SPARC
www.embopress.org/doi/full/10....
#quotes #books #booksky #excerpts #citations #sexatdawn #ryan #jetha #sex #women #dependency #semen #estrogen #prostaglandin #testosterone #boost #vagina #psychologist #psychology #biochemistry #wearedrugs
My luteal phase superpower: the amazing ability to immediately recognize the smell of Yankee Candle Clean Cotton® leaking from the seams of a suburban Honda CR-V
#ovulation #prostaglandin #yankeecandle
