What if the real #breakthrough isn’t stopping #ProteinAggregation, but intelligently redirecting its pathway? Explore the insightful review: doi.org/10.63654/icm... #Sustainable #TherapeuticInnovation #AmyloidAggregation #ProteinMisfolding #ComputationalBiology #NeurodegenerativeDiseases
This #STTT review provides a comprehensive overview of #ProteinFolding biology, detailing the roles of key #MolecularChaperones, the multifactorial causes of #ProteinMisfolding, and emerging therapeutic innovations targeting #Proteostasis.
#OpenAccess: doi.org/10.1038/s413...
Why Some Parkinson’s Disease Medications Stop Working
How do Parkinson’s drugs work, and why do they stop working as the disease progresses?
🎧 Watch Episode #5 with Prof. Outeiro to learn about #Parkinsons, #ProteinMisfolding, and #NeurodegenerativeDiseases:
▶️ youtu.be/UF4h07lml0M?...
#Medsky🧪 #neurosky #immunosky Studies are investigating a link between #proteinmisfolding in GIT & the development of #neurodegenerativediseases like #Parkinson & #Alzheimer often years before symptoms appear.
'Skin biopsy: an emerging tool for the diagnosis of #proteinmisfolding diseases of the central nervous system'
Wei Zhu, Hao-Lun Sun, Yan-Jiang Wang, Xia Lei, Xian-Le Bu #alphasynuclein #neurodegeneration
molecularneurodegeneration.biomedcentral.com/articles/10....
🚨 New paper!
Montepera et al. from Giorgia Brancolini’s group show how the K141E mutation boosts HSPB8 flexibility, destabilizing it and driving motor neuropathy.
📖 buff.ly/w33LzJB
#HSPB8 #ProteinMisfolding #Neuropathies
We are pleased at JBSD that Professor Vladimir Uversky (University of South Florida), a pioneer in intrinsically disordered proteins and protein misfolding, is continuing with us as an Editorial Board member. #JBSD #IDPs #ProteinMisfolding t.co/HSFBiCZfM5
