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CRISPR-Cas9 targeting of G-Quadruplex DNA in ADH1 promoter highlights its role in transcriptome and metabolome regulation url: academic.oup.com/nar/article/...
Grateful for all the hard work from my team. #yeast #quadruplex #metabolomics

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Structural Insights into Spare-Tire DNA G-Quadruplex from the Human VEGF Promoter The vascular endothelial growth factor (VEGF) promoter region, which is involved in cancer progression, contains guanine-rich sequences capable of forming G-quadruplex (G4) structures. G4s play a crit...

Another publication on DNA G-quadruplexes in collaboration with the Heckel group is out! ๐ŸŽ‰

"Structural Insights into Spare-Tire DNA G-Quadruplex from the Human VEGF Promoter"

Full text: pubs.acs.org/doi/10.1021/...

#G4 #quadruplex #photocages #NMR #VEGF #structure

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Big milestone from our team! Congrats to all!
Photodynamic Therapy Using a Heavy-Atom-Free G-Quadruplex-Targeted Photosensitizer to Efficiently Regress Rhabdomyosarcoma Tumors In Vivo
pubs.acs.org/doi/10.1021/...
#quadruplex #G4 #DNA #cancer #zebrafish

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G-quadruplexes and their unexpected ability to fold proteins | PNAS G-quadruplexes and their unexpected ability to fold proteins

Have a look at our newest commentary in @pnas.org :

"G-quadruplexes and their unexpected ability to fold proteins"

Full text: www.pnas.org/doi/10.1073/...

#G4 #quadruplex #proteins #folding

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Definition of quadruplex quadruplex having four units or componentsnnn #definition #meaning #quadruplex #ielts #learnenglish #education #british

quadruplex
- Having four units or components

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#definition #quadruplex #meaning #english #ielts

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Interested in G-quadruplexes, check out "Early events in G-quadruplex folding captured by time-resolved small-angle X-ray scattering" #DNA #Quadruplex ๐Ÿ‘‰ Read the full article here: https://buff.ly/3Q2whFW

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Thrilled to show you that #iMab antibody selectively binds to #iMotifs (intra- AND intermolecular). This was very challenging but satisfying.
Can't wait to see what's next with iMotifs!
Thanks to all collaborators! #DMM_Unipd #GarvanInstitute #SloNMR
๐Ÿ‘‰ academic.oup.com/nar/article/53โ€ฆ
#quadruplex

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@Veddic 2002 #DNA#quadruplex discovery - view here
http://youtu.be/9t9K0BiSS20
or the short and sweet version
http://youtu.be/4vzluTEPy9s
Enjoy elegance!

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