Volume 214 Issue 11 | The Journal of Immunology | Oxford Academic The JI publishes peer-reviewed manuscripts describing novel findings in all areas of experimental immunology, including both basic and clinical studies.

The latest issue of The JI is now online! Read cutting edge research, brief reviews, and more.

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#ReadTheJI #Immunology

A special collection on #aging and the immune system highlights the expanding field of immune aging, featuring an invited commentary from a pioneer in the field and a collection of 5 brief reviews from leaders in aging research. Read the editorial: ow.ly/qxyM50W6fAx. #ReadTheJI

High fat diet feeding impairs neutrophil phagocytosis, bacterial killing, and neutrophil-induced hematopoietic regeneration Abstract. The prevalence of obesity and metabolic diseases have risen significantly over the past decades. Chronic inflammation in obesity is a link betwee

New in The JI: High fat diet feeding impairs neutrophil phagocytosis, bacterial killing, and neutrophil-induced hematopoietic regeneration. #ReadTheJI #immunology

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Aging and neurodegeneration: when systemic dysregulations affect brain macrophage heterogeneity Abstract. Microglia, the major population of brain resident macrophages, differentiate from yolk sac progenitors in the embryo and play multiple nonimmune

New Brief Review: Aging and neurodegeneration: when systemic dysregulations affect brain #macrophage heterogeneity. #ReadTheJI #immunology

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PVR exposure influences the activation, adhesion, and protein expression of human CD8+ T cells, including the CD96-mediated transfer of PVR Abstract. Poliovirus receptor (PVR) ligands have gained attention as immunotherapy targets, yet their regulation remains unclear. Here, we examine the impa

#ICYMI: Poliovirus receptor (PVR) exposure influences the activation, adhesion, and protein expression of human CD8+ T cells, including the CD96-mediated transfer of PVR. ow.ly/iMkr50VbSXy

#ReadTheJI #immunology

Modulation of germinal center and antibody dynamics via ipsilateral versus contralateral immunization against SARS-CoV-2 Abstract. Human clinical trials have reported immunological outcomes can differ between ipsilateral (same side) and contralateral (alternate sides) prime-b

New research from @thedohertyinst.bsky.social suggests that receiving multiple doses of a vaccine in the same limb leads to faster antibody development, an important strategy for providing #immunity quickly during a pandemic or disease #outbreak. #ReadTheJI #immunology

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#ICYMI: Characterization and comparison of immunity against MPXV for individuals infected with MPXV or vaccinated with modified vaccinia Ankara vaccines. #ReadTheJI #immunology

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Congratulations @pamelialim.bsky.social!

#ReadTheJI #immunology

Discover how #aging impacts changes in #Tcell subpopulations, transcriptomes, and TCR repertoires in overall and antigen-specific T cell populations.

Read it here 👉https://ow.ly/jzf950VaBFv

#ReadTheJI #immunology

Impact of sleep deprivation on monocyte subclasses and function Abstract. The relationship between sleep deprivation, obesity, and systemic inflammation is a critical area of investigation due to its significant impact

ICYMI: One day of sleep deprivation can alter your immune system and increase inflammation. Read how sleep deprivation can impact monocyte subclass and function 👉 ow.ly/6pei50V65JJ

#ReadTheJI #immunology

Immunometabolic Mechanisms of LANCL2 in CD4+ T Cells and Phagocytes Provide Protection from Systemic Lupus Erythematosus Key Points. LANCL2 activation induces anti-inflammatory effects in CD4+ T cells and phagocytes.NIM-1324 activates LANCL2 to reduce proteinuria and disease

#ICYMI: Immunometabolic Mechanisms of LANCL2 in CD4+ T Cells and Phagocytes Provide Protection from Systemic Lupus Erythematosus. Read the article in @jimmunol.bsky.social: ow.ly/9lWX50V3yAx.

#immunology #ReadTheJI

The January Issue of #TheJI is available now! Read the latest in #immunology research here 👉https://academic.oup.com/jimmunol/issue/214/1

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Taking vitamin E during pregnancy may decrease peanut allergy in children  - AAI News New research found that supplementing maternal diet with α-tocopherol, a form of vitamin E, can reduce the development of food allergy and anaphylaxis in newborn mice.

#NewResearch from Indiana University School of Medicine published in The Journal of Immunology found that supplementing maternal diet with a form of vitamin E can reduce #foodallergy and anaphylaxis in newborn mice. Discover more: ow.ly/NvGQ50V31ec. #ReadTheJI

The Journal of Immunology’s latest Top Reads are now live!  Explore these groundbreaking studies showcasing the breadth of #immunology. #ReadTheJI #transplantation #clinical #obesity

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