Homologous series of previously overlooked polymerization byproducts (H-PFCAs) detected near fluoropolymer production plant using #SIRIUS6.
#SIRIUSDiscoveries #PFAS #Fluoropolymers
💡 Blog post: buff.ly/P9grMJQ (3 min)
📄 Publication: buff.ly/a960M9n
Using #SIRIUS6, researchers found the #Biopesticide 6-PP to be produced via the polyketide biosynthesis pathway in Trichoderma fungi. This finding may pave the way for developing improved biocontrol agent. #SustainableAgriculture
💡 SIRIUS discoveries: buff.ly/HP0dTWO
📄 Publication: buff.ly/J5JE4Tk
Metabolic adaptations of a salt-tolerant willow are specific to the plant organ and the salt anion. The researchers used #SIRIUS6 to identify the chemical structures of unknown compounds from mass spectrometry data.
💡 SIRIUS discoveries: buff.ly/HP0dTWO
📄 Publication: buff.ly/plLgOGE
#NonTargetedAnalysis #ChemicalClassification with #SIRIUS6 identifies cell surface glycans & membrane lipids as influential drivers of adaptation to heat stress in rice coral hosting thermosensitive and thermotolerant symbionts.
💡 SIRIUS discoveries: buff.ly/HP0dTWO
📄 Publication: buff.ly/KeqUClP
Unlocking the secrets of healing mushrooms 🍄
#SIRIUS6 was instrumental in detailing the metabolic basis for the production of sesquiterpenoids in the #MedicinalMushrooms Sanghuangporus.
#SIRIUSDiscoveries #NaturalProducts
💡 More SIRIUS discoveries: buff.ly/HP0dTWO
📄 Publication: buff.ly/RDAMNtB
Hidden Players in Drug Efficacy: Using #SIRIUS6, researchers decoded the crucial role of the gut microbiome in altering the chemical structure and efficacy of GPCR drugs.
💡 Blog post: buff.ly/WtrJf2m (5 min)
📄 Publication: buff.ly/8o1ekPv
#SIRIUSDiscoveries #DrugMetabolism #PersonalizedMedicine
Based on this tutorial our software #SIRIUS6 plays a significant role in prioritization strategies for #NonTargetScreening in environmental samples by generating molecular fingerprints which are used for compound identification or toxicity prediction.
📄 Read the tutorial: buff.ly/M9gNmBR
🌱 The quest to enhance long-term soil carbon storage 🌏
#SIRIUS6 #CompoundClassPrediction was essential for annotating 80% of the previously unknown metabolite features of tall wheatgrass root exudates.
💡 More #SIRIUSDiscoveries: buff.ly/HP0dTWO
📄 Publication: buff.ly/sYB1nPm
How can we assess the risk of a compound we can't even name?
SIRIUS molecular fingerprints serve as crucial inputs for predictive models, such as #ToxicityPrediction, even when the exact identity of a compound is unknown.
📄 doi.org/10.1016/j.en...
#SIRIUSFacts #SIRIUS6 #NonTargetAnalysis
#SIRIUS6 in a #NonTargetedAnalysis to identify unknown chemical compounds with potential estrogenic activity to investigate the link between #DrinkingWater #contaminants and #BreastCancer incidence.
▶️ Try SIRIUS now: buff.ly/K8wQ3ER
💡 Original publication: buff.ly/SZ2LPbp
#SmallMoleculeID
Untargeted #metabolomics using #SIRIUS6 is mapping the #InternationalSpaceStation
Most extensive look yet at the microbial and chemical landscape of the ISS.
💡 Blog post: buff.ly/nGt934u (5 min)
📄 Original publication: buff.ly/s8BBclb
▶️ Try #SIRIUS6 now: buff.ly/K8wQ3ER
#SIRIUSDiscoveries
#SIRIUS6 compound class prediction helps to validate ethanol extraction for human faecal #metabolomics as a valid, safer, and more economical alternative to the common methanol extraction.
▶️ Try SIRIUS now: buff.ly/x7dNWAR
📄 Publication: buff.ly/cGkUOyi
#SIRIUSDiscoveries #Microbiome
New study from the long-running @jena-experiment.bsky.social challenges core ecological assumption: that in a diverse ecosystem, plants can save energy on defenses and focus on growth.
📄 Blog feature: buff.ly/LgCEGpL
📄 Publication: buff.ly/u6lzwUe
#SIRIUS6 #SIRIUSDiscoveries #NonTargetedAnalysis
In this #NonTargetedAnalysis utilizing SIRIUS, researcher successfully identify common and previously unreported chemical contaminants in human milk, including novel parabens.
Blog post: buff.ly/0vQizvG
Paper: buff.ly/Mg8axQF
#SIRIUS6 #StructureElucidation
MCheM integrates online chemical labeling reactions directly into the LC-MS/MS workflow to provide structural information which is fed into #SIRIUS6 via @mzmine.bsky.social to significantly constrain the molecular structure search space and boost annotation accuracy.
Learn more: buff.ly/iib0L6I
🧠 ✏️ Your chemical intuition, now integrated into #SIRIUS6.
Have you tried the new Structure Sketcher yet?
▶️ Watch our new YouTube tutorial to learn how to use the Structure Sketcher and elevate your annotation process: www.youtube.com/watch?v=_byB...
#HowToSIRIUS #SmallMoleculeID #MassSpec
Do you ever look at the best hit from a structure database search and instantly know how to improve it?
In #SIRIUS6, your chemical intuition just got a powerful new tool: the Structure Sketcher.
buff.ly/c4cfGvW
#HowToSIRIUS #SmallMoleculeID
⚠️ Important Announcement for SIRIUS 5 Users! ⚠️
Maintenance and support for SIRIUS 5 will officially end on 🗓️ February 28, 2026.
To ensure you continue to benefit from the latest advancements, we highly recommend upgrading to #SIRIUS6: buff.ly/91GQKjH
#SIRIUSSoftware #SmallMoleculeAnnotation
Explore the new features and elevate your mass spectrometry data analysis.
⬇️ Learn more and download SIRIUS v6.3 today: lnkd.in/ejcaedSw
#SIRIUS6 #SIRIUSUpdate #MassSpectrometry #MSsoftware #LCMSMS #SmallMoleculeIdentification #StructureElucidation #Biotransformation #MachineLearning
🚀 SIRIUS v6.3 is here!
We're excited to introduce the latest version of #SIRIUS with powerful new features to enhance small molecule identification.
⬇️ Learn more and download SIRIUS v6.3 today:
bright-giant.com/sirius-relea...
#SIRIUS6 #MSsoftware #MassSpectrometry #SmallMoleculeIdentID
Test your #SIRIUS6 knowledge! 🧠
❓ The SIRIUS software uses an ILP solver to perform which specific task ❓
Drop a comment with your answer! The correct answer will be revealed on Friday.
Learn more about #SIRIUSSoftware: buff.ly/vBOiq3F
#SmallMoleculeID #StructureElucidation
SIRIUS identifies potentially allergenic transformation products of tattoo pigments in new online-LC-EC-MS approach that overcomes the challenge of impure pigment standards by separating pigments from impurities before simulating their metabolism. #SmallMoleculeID #SIRIUS6 doi.org/10.1007/s002...
🚨 Detecting deadly nitazenes just got easier. A new study uses untargeted LC-HRMS + #SIRIUS6 to ID key phase I/II metabolites, boosting opioid detection. Advanced #MSsoftware + #MachineLearning are shaping the future of #Toxicology. #DrugDiscovery #SIRIUSDiscoveries doi.org/10.3390/meta...
🚀 Great turnout at our #SIRIUS6 workshop at #MetSoc2025. 80+ attendees & a lively Q&A! We showcased how SIRIUS goes beyond spectral libraries with structure generation & analog search. Missed it? Let’s connect at booth T11.
#MassSpectrometry #Metabolomics #AutomatedAnnotation
More first-hand insights from the #SIRIUSCommunity on the third day of #MetSoc2025.
Don't miss the opportunity to get in touch!
#SIRIUS6 #MetaboliteAnnotation #SmallMoleculeID #MassSpectrometry #SIRIUSEvents
Novel transformation product annotation with #SIRIUS6 - Don't miss this talk at #MetSoc2025 !
🎤 @mfleischauer.bsky.social
📅 June 25 | 4:30 p.m. – 4:50 p.m.
📍 Congress Hall | Abstract #471
#Metabolomics #LCMSMS #SmallMoleculeID #TransformationProducts #MassSpectrometry #StructureAnnotation
🗓️ Plan your Tuesday: Gain first-hand 👌 SIRIUS insights at #MetSoc2025
Make sure to mark your calendars for these talks and posters from the #SIRIUSCommunity
#SIRIUS6 #MetaboliteAnnotation #SmallMoleculeID #MassSpectrometry #SIRIUSEvents
We’re thrilled to share our SIRIUS contributions at #Metabolomics2025 in Prague! 🇨🇿
We can’t wait to engage with the #metabolomics community, share our expertise, and showcase how #SIRIUS6 is empowering more confident, comprehensive analyses.
#MetaboliteAnnotation #MassSpectrometry
We are excited to announce our new Short Course Tutorial Series on YouTube that will guide you through the essential features of #SIRIUS6 to help you get the most out of your data.
Watch the full playlist here: bright-giant.com/short-course... and don't forget to subscribe!
#HowToSIRIUS
Transform your #SmallMoleculeAnalysis with #SIRIUS6!
Identify bioactive substances, drug leads, contaminants, ...
Annotate molecular structures beyond spectral libraries.
Analyze smarter. Discover faster.
📥 Download now: bright-giant.com/links/
www.youtube.com/watch?v=teFZ...
#MassSpectrometry
