A viral #mitochondriopathy plays an important role in the pathophysiology of #covid infection.
Early in the infection, #SARSCoV2 induces a widespread transcriptomic dysregulation of nuclear-encoded mitochondrial genes & the viral proteins also interact with the host

along with expression of markers which correlate with mitochondrial dysfunction. To investigate the mechanistic basis of these mitochondrial abnormalities in acute & #longCOVID, several studies have examined how #SARSCoV2 directly perturbs host #mitochondrialmetabolism

Frontiers | The association between peritraumatic distress, perceived stress, depression in pregnancy, and NR3C1 DNA methylation among Chinese pregnant women who experienced COVID-19 lockdown Abstract Prenatal stress can affect pregnant women in an epigenetic way during the critical period of conception of their offspring. The study aims to invest...

www.frontiersin.org/journals/imm...

www.mdpi.com/1422-0067/26...
Evidence Gaps: No consistent identification of specific epigenetic modifications uniquely attributable to #SARSCoV2

www.mdpi.com/2077-0383/14...

www.jaacap.org/article/S089...

-Neuroimaging: VBM, DTI, ASL perfusion MRI, and FreeSurfer software enable sensitive detection of brain structure/function changes
-Functional MRI: Useful for assessing brain function and lateralization; role in #SARSCoV2 exposure under investigation

* Combining standardized neurodevelopmental assessments with advanced neuroimaging offers a comprehensive approach to detect subtle effects of neonatal #SARSCoV2 antibody exposure.
-Neurodevelopmental Tools: HINE, AIMS, APIB, NNNS, TIMP, GMs, RNDA are validated for early detection of subtle delays

🔥Neurodevelopmental Outcomes in Children Exposed to Maternal #SARSCoV2
Short-Term Neurodevelopmental Outcomes
🧨General Findings: Most infants show normal development at 6–12 months; ~10% exhibit delays, especially with first/second trimester exposure

Longitudinal Evaluation of Antibody Persistence in Mother-Infant Dyads After Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy In a longitudinal cohort of 256 pregnant women with COVID-19, maternal/infant sera were collected up to 6 months postpartum. Predelivery vaccination was hi

@jidjournal.bsky.social
academic.oup.com/jid/article/...

medicinamoderna.ro/wp-content/u...
Neonatal #SARSCoV2 IgG is primarily acquired via efficient transplacental transfer, with timing of maternal exposure & vaccination status being critical determinants.

👶 Antibody Profiles Following Maternal #SARSCoV2 Infection
Presence & Levels of IgG & IgM in Newborns
- IgG: Efficiently detected in neonates born to infected or vaccinated mothers, reflecting robust transplacental transfer.

Transplacental Transfer of SARS-COV-2 Antibodies The transfer of immunoglobulins from the mother to her fetus is the major defensive tool of the neonate against infectious diseases during the first few months of life. The mechanism of antibody trans...

Understanding the efficiency and characteristics of this antibody transfer in the context of #SARSCoV2 & its implications for neurodevelopmental outcomes, is essential for guiding maternal vaccination strategies and early childhood monitoring
link.springer.com/chapter/10.1...

#Medsky🧪 #pedsky #obsky #immunosky #IDsky #Vaccinematters #publichealth
The #COVID19pandemic has raised critical questions about the impact of maternal #SARSCoV2 infection during pregnancy on both passive immunity in newborns & subsequent child neurodevelopment.

Find Out Which Major Sports League Is Slammed With Illness & Injuries!

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=AOqg...

#SARSCoV2 🇩🇪 Osterferien sind vorbei

👉Trend ↗❓ s.ALT
Maximalwerte wieder aus Zwickau

keine neuen Fälle meldeten:

Flensburg seit 13.Feb
Bremen
Wolfsburg seit 14.Feb
Stade
Mönchengladb.
Wiesbaden
Coburg
Dachau seit 28.Feb
Erlangen
Ingolstadt
Berlin-Kreuzberg +Charlottenb.
Brandenburg/Havel
Oberhavel

'Today is March 2234, 2020.' (bold sans-serif text at center) (bottom small circle with line thru it and inverse colored letters for covid action network): c A n.

#CovidIsntOver #SARSCoV2 https://covid.aktion.network

New Covid Variant And Wastewater Data Is Just In from The US CDC

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=d_H2...

Here's the latest variant picture for Canada, to late March.

XFG.* "Stratus" remained dominant, rebounding to 55% frequency.

NB.1.8.1 "Nimbus" fell to 35%.

#COVID19 #SARSCoV2 #Canada #XFG #Stratus #NB_1_8_1 #Nimbus
🧵

'Today is March 2233, 2020.' (bold sans-serif text at center) (bottom small circle with line thru it and inverse colored letters for covid action network): c A n.

#CovidIsAirborne #SARSCoV2 https://covid.aktion.network

Here's the latest variant picture for the United States, to late March.

The XFG.* "Stratus" variant remained dominant, but fell to 62%.

BA.3.2.* "Cicada" has debuted in the top 7 lineages, growing strongly to 12%.

#COVID19 #SARSCoV2 #USA
🧵

Here's the latest variant picture for Australia, to late March.

Several variants are churning around in a confused picture, without any one being clearly dominant.

NB.1.8.1.* "Nimbus" rebounded to 40%.

BA.3.2.* "Cicada" rebounded to 33%.

#COVID19 #SARSCoV2 #Australia
🧵

Read More: substack.com/profile/4049...
#science #meded #sarscov2

Covid Is At It's Lowest In A Very Long Time, Will It Last Much Longer?

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=EMpC...

#Medsky #IDsky #pedsky #publichealth Maternal #SARSCoV2 infection during pregnancy is associated with altered immune profiles in newborns, primarily through the transplacental transfer of IgG antibodies.

'Today is March 2232, 2020.' (bold sans-serif text at center) (bottom small circle with line thru it and inverse colored letters for covid action network): c A n.

#CovidIsntOver #SARSCoV2 https://covid.aktion.network

#SARSCoV2 in Berlin weit(er)hin still:

data.lageso.de/infektionssc...

New Report Shows Long Covid Is Costing Billions of Dollars Every Year!

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=6p2b...

Thread by @ZdenekVrozina on Thread Reader App @ZdenekVrozina: Long COVID research badly needs studies that move beyond description and toward intervention. This is why this preprint is worth attention. It starts to sketch a possible treatment path.🧵 A new prepr...…

#ZdenekVrozina on X wrote:

Long COVID research badly needs studies that move beyond description and toward intervention. This is why this preprint is worth attention. It starts to sketch a possible treatment path.🧵threadreaderapp.com/thread/20423582201449679...

#LongCovid #SarsCoV2

'Today is March 2231, 2020.' (bold sans-serif text at center) (bottom small circle with line thru it and inverse colored letters for covid action network): c A n.

#CovidIsAirborne #SARSCoV2 https://covid.aktion.network

The Truth Is Everything Is Not Fine And Ok, You Need To Be Informed!!

#COVID19 #SARSCoV2 #Pandemic #CovidIsNotOver #CovidIsAirborne #H5N1 #Measles #WhoopingCough #RSV #Norovirus #Tuberculosis #Polio #Mpox #MaskUp #N95 #KeepMasksInHealthcare

www.youtube.com/watch?v=INoM...

'Today is March 2230, 2020.' (bold sans-serif text at center) (bottom small circle with line thru it and inverse colored letters for covid action network): c A n.

#CovidIsntOver #SARSCoV2 https://covid.aktion.network

SARS-CoV-2 directly infects the inner ear and causes hearing dysfunction SARS-CoV-2 directly infects spiral ganglion neurons in the inner ear, causing apoptosis and hearing loss. Liu et al. show that the spike protein inhibits mTOR signaling, inducing aberrant stress granu...

«Studien zeigen: SARS-CoV-2 kann das #Gehör schädigen. In Mäusen dringt das Virus #ins Innenohr ein und greift Nervenzellen an. Das Spike-Protein stört wichtige Zellprozesse, was zum Zelltod führt. Hörverlust kann so auch ohne Entzündung entstehen.»

www.cell.com/cell-reports...

#COVID19 #SARSCoV2

Warum schwere Infektionen erhebliche Spätfolgen haben können Schwer verlaufende Infektionskrankheiten wie Grippe oder Covid können schwerwiegende Folgeerkrankungen nach sich ziehen. Forschende wissen jetzt, woran das liegt - und raten deshalb zu bestimmten Schu...

#LuftHygiene #CleanAir #SaubereLuft #CovidIsAirborne #CovidIsntOver #C19 #SARSCoV2 #RSV #Influenza #Grippe #LuftuebertrageneViren #HEPA13Filter

Schwer verlaufende Infektionskrankheiten wie Grippe oder Covid können schwerwiegende Folgeerkrankungen nach sich ziehen👇
www.n-tv.de/wissen/Warum...