Additive and Multiplicative Effects of Socially Stigmatized Identities Using Linear Regression to Model Effects on Self-Reported Overall Health as Reported in the All of Us Research Program: Quantitative Analysis Background: Individuals with one or more socially stigmatized identities experience extensive health disparities, resulting in poorer health outcomes. However, most studies consider the effects of only individual stigmatized identities. Objective: We aimed to quantitatively estimate the additive and multiplicative effects of stigmatized identities on self-reported overall health. Methods: We used survey data from 387,411 participants in the All of Us Research Program, which has assembled a disease-agnostic cohort intended to reflect the US population, to statistically estimate the first- and second-order effects of 47 stigmatized identities on self-reported overall health. We used a linear model to estimate the effects of individual and pairwise stigmas on self-ratings of overall health. Results: We began by aiming to create cohorts for all 93 stigmatized identities previously found to affect health, of which 47 (51%) could be practicably examined. We first modeled individual stigmas alone to contrast the results with those that included both individual and pairwise stigmas. After using the false discovery rate to adjust for testing multiple hypotheses in the collective model, 29 individual and 116 pairs of stigmas had statistically significant effects on self-reported overall health. All significant individual effects were negative or neutral except for skin #Cancer. Those with the largest negative effect on self-rated overall health were difficulty walking or climbing stairs, unemployed or unable to work, difficulty with errands, and low educational attainment. Pairs of intersecting stigmas had a mix of negative and positive incremental effects, indicating that some stigmatized identities are negative modifiers, such as depression, and other combinations are less negative than the sum of their individual negative effects, such as having difficulty with multiple types of activities of daily living. The individual stigmas with the largest number of statistically significant stigma pairs were unemployed or unable to work (14/47, 30%); depression and low income (11/47 each, 24%); and difficulty walking or climbing stairs, cognitive difficulties, obesity, and skin #Cancer (8/47 each, 17%). Conclusions: Taken together, numerous pairs of stigmatized identities significantly affect self-reported overall health. While each stigmatization has both direct and indirect effects on health, the relative importance of direct and indirect effects will vary. Many of these are aligned with prior literature, and others warrant further exploration. While the large sample size of this study is a strength, we were unable to model higher-order intersectionality and encourage future research exploring this. The individual and pairwise identities with significant negative effects should be incorporated into research and clinical care by considering the multidimensionality of individuals and how that affects their overall health.

JMIR Formative Res: Additive and Multiplicative Effects of Socially Stigmatized Identities Using Linear Regression to Model Effects on Self-Reported Overall Health as Reported in the All of Us Research… #SocialHealth #StigmatizedIdentities #HealthDisparities #QuantitativeResearch #LinearRegression

Good news: 94% of patients are open to being asked about social isolation in clinical settings. Just ask!

ddressing isolation isn’t one-size-fits-all. The solution could be as simple as a hearing aid or helping someone find a social group.

#SocialHealth #HumanConnection #UCSF

Many clients already had doctors and therapists.

What they needed was a connection and programs that didn’t feel clinical.

magazine.ucsf.edu/prescription...
#SocialHealth #HumanConnection #UCSF

UCSF researchers found a peer program where clients described their peers as friends made a huge impact.

Trust matters! magazine.ucsf.edu/prescription...

#SocialHealth #HumanConnection #UCSF

A Prescription for Loneliness What a tiny grassroots program in the Tenderloin is teaching doctors about healing through human connection.

Loneliness and isolation are health issues too, but addressing them often starts outside the doctor’s office.

Here’s how: magazine.ucsf.edu/prescription...
#SocialHealth #HumanConnection #UCSF

Truth is not only ethical — it is biological.
(Karl Friston (2010)The free-energy principle: a unified brain theory? Nature Reviews Neuroscience)
#TruthMatters #CompassionateLeadership #CultureOfTruth #IntegrityInAction
#ScienceOfTrust #Neuroscience #EpistemicTrust #SocialHealth

Breaking the Silence: How Social Connection Fights Loneliness World Health Organization has declared loneliness a “global public health issue,” noting that loneliness and social isolation can be more harmful than

Connection is the Antidote to Silence. 🤝✨
​In a world that’s more connected than ever, why do we feel so lonely? Breaking the silence isn't just about talking 👉 www.hopetotalk.info/2026/03/brea...

#MentalHealthAwareness #SocialHealth #EndTheStigma
#SocialConnection #BreakTheSilence

Are socially isolated people more likely to develop cancer? Study of 350,000 adults explores the risk A large UK Biobank study of more than 350,000 adults found that social isolation, but not loneliness alone, was associated with a modest increase in overall cancer risk during over 11 years of follow-...

🔬 Can your social circle affect your cancer risk? A study of 350,000 adults found social isolation may increase cancer risk, especially for women. www.news-medical.net/news/2026030... #Cancer #SocialHealth

Having “hasslers” in your network linked to faster aging and poorer health Researchers analyzed a state-representative US sample to examine whether negative social ties, termed “hasslers,” are associated with epigenetic age acceleration and faster biological aging. Each addi...

😳 Just one "hassler" in your social network may speed up your biological aging and harm mental health, says new research.

Negative ties could be more impactful than you think.

www.news-medical.net/news/2026022... #MentalHealth #Aging #SocialHealth @pnas.org

💕 Does oxytocin help wounds heal faster? Not on its own.

In 80 healthy couples, intranasal oxytocin accelerated wound healing only when paired with affectionate touch and partner appreciation.

Oxytocin acts as a "social amplifier".

buff.ly/IvuBcTq

#Oxytocin #SocialHealth #RelationshipScience

How can people live like that!?"

I MEAN WHAT THE FUCK⁉️⁉️⁉️
HER House is such a FUCKING SHIT PIT‼️‼️‼️
I Just... (WE ***NEED!!!*** AN EMOJI PULLING IT'S HAIR OUT🤬🤬🤬🤬🤬🤬🤬🖕🏼🖕🏼🖕🏼🖕🏼🖕🏼🖕🏼🖕🏼‼️‼️‼️‼️‼️‼️‼️)

#HOARDERS #HOARDING #HOARD #PackRat #PackRatting #WTF #WhatTheFlyingFuck⁉️⁉️⁉️#⁉️ #MentalHealth #SocialHealth #MentalIllness

House committee backs definition of 'social health' and moves social‑health bill forward after debate HB 3.17 (first substitute as amended) narrowly defines 'social health' and ties it to existing health curriculum; committee recommended the substitute 8–4 after testimony from school leaders who credited social‑health instruction with reducing suicides and improving student wellbeing.

A new bill aims to define 'social health' in schools, linking it to life-saving programs that have improved student wellbeing and reduced suicides.

Click to read more!

#UT #CitizenPortal #EducationReform #SocialHealth #MentalHealth

Psychology study reveals how gratitude can backfire on your social standing New research suggests that expressing intense gratitude can lower observers' perceptions of your status. The study found that effusive thankers are often viewed as having less power than the people they thank.

Psychology study reveals how gratitude can backfire on your social standing #Science #HealthandMedicine #MentalHealth #Gratitude #Psychology #SocialHealth

www.psypost.org/psychology-study-reveals...

UCSF researchers found a peer program where clients described their peers as friends made a huge impact. Trust matters!

magazine.ucsf.edu/prescription...
#SocialHealth #HumanConnection #UCSF

A Prescription for Loneliness What a tiny grassroots program in the Tenderloin is teaching doctors about healing through human connection.

Loneliness and isolation are health issues too, but addressing them often starts outside the doctor’s office.

Here’s how: magazine.ucsf.edu/prescription...
#SocialHealth #HumanConnection #UCSF

बढ़ती अविवाहित प्रवृत्ति और मानसिक स्वास्थ्य : एक गंभीर .. शादी का बंधन केवल दो लोगों का मिलन नहीं, बल्कि एक संवेगात्मक सम्बल का साधन है। कुछ लोग जीवन भर अविवाहित रहकर किसी विशेष कार्य के लिए स्वयं को समर्पित कर देते...

बढ़ती अविवाहित प्रवृत्ति के साथ मानसिक स्वास्थ्य चुनौतियाँ भी तेज़ी से उभर रही हैं। अकेलापन, अवसाद और सामाजिक दबाव आज एक गंभीर मुद्दा बन चुके हैं।
Read more 👇
avknewsservices.com/2026/01/23/r...

#MentalHealth #Marriage #SingleLife #Loneliness #IndianYouth #SocialHealth #AVKNewsServices

We’re excited to welcome Prof Daisy Fancourt (UCL) to BSPHN26, where she’ll share pioneering research on how social connections & behaviours shape health & wellbeing in dynamic, real-world environments.

Get your ticket today! 👇
#BehaviouralScience #ComplexityThinking #SocialHealth #ArtCure #BSPHN26

Are you thinking about volunteering this year? Read Natasha's story about her experience giving her time to Together Co as a befriender. eu1.hubs.ly/H0qFNXt0

#Befriending #Volunteering #SocialHealth

What Is Health? - QA Realm Forum Global Q&A Hub. Ask, Answer, Connect.

What Is Health? - QA Realm Forum
qarealm.com/d/16-what-is...

Tags: #What, #Health, #QA, #Realm, #Forum, #Health #HolisticHealth #Wellness #PhysicalHealth #MentalHealth #SocialHealth #PublicHealth #HealthyLiving #Wellbeing #LifestyleMedicine #PreventiveHealth

KINDNESS + HAPPINESS 8/10
Practicing kindness strengthens social bonds and fosters emotional well-being 🤝. A ripple effect that expands far beyond the original action.
#SocialHealth #CompassionCulture #MeaningfulImpact

Stronger Social Networks May Add Years to Life, Studies Find New 21-year study finds older adults with strong social networks lived 2 years longer. Friends and neighbors predicted better survival than family alone.

🤯 New 21-year study reveals strong social networks add 2 years to your life, and friends predict better survival than family alone.

#Longevity #HealthyAging #SocialHealth #Biohacking

biohackingnews.org/lifestyle/so...

New studies show that broader social support networks may slow aging, extend lifespan and improve quality of life for older adults.

longevity.technology/news/new-stu...

#longevity #agingwell #socialhealth #lifespan #wellbeing

UCSF researchers found a peer program where clients described their peers as friends made a huge impact.

Trust matters!

magazine.ucsf.edu/prescription...
#SocialHealth #HumanConnection #UCSF

A Prescription for Loneliness What a tiny grassroots program in the Tenderloin is teaching doctors about healing through human connection.

Loneliness and isolation are health issues too, but addressing them often starts outside the doctor’s office.

Here’s how: magazine.ucsf.edu/prescription...
#SocialHealth #HumanConnection #UCSF

MolotoffCockatiel - Twitch 🔥🎂it's my heckin birthday, come in here and celebrate🔥 !chirp !discord

experimental midnight stream. gonna play a lil new game here..

www.twitch.tv/molotoffcock...

#gaming #streaming #vtuber #morsels #mentalhealth #socialhealth

Loneliness, Isolation Affect One Third of US Adults Over 50 Loneliness and social isolation have declined since the pandemic but still affect about one third of US adults aged 50-80 years, a new study shows.

1 in 3 U.S. adults over 50 reports feeling lonely or isolated, with rates higher among those living alone or in poor health. Screening for social connection should be as routine as diet and exercise checks. @Medscape
www.medscape.com/viewarticle/...
#HealthyAging #SocialHealth #AgelessAging

Emotional intelligence, strong relationships, and social connections are crucial for happiness. Intelligent individuals sometimes struggle here, perhaps overthinking social interactions or finding it difficult to relate to others. #SocialHealth 5/6

Schluesserkenntnis einer weltweiten #Psychiatrie Expertenbefragung:
No #mentalhealth w/o #socialhealth
Thomas Ihde
#sby2025 #standbyyou #kunsthaus

The next time you find yourself out in your local community (ahem, like later today), take a moment to have a conversation with your fellow neighbor. 👋

Try this tiny action today to strengthen your social health muscle. 💪

#MicroMoments #SocialHealth #Belonging
#Trust #Support #Participation

Get rid of your triple chin by looking up from you phone, be aware of those around you, and for goodness sakes throw a smile.
Try this tiny action today to strengthen your social health muscle.
#SocialHealth #Belonging #Trust #Support #Participation #SocialHealthGym #MicroTip #Kindness #Community