Thromboxane A2 receptor activation in dendritic cells protects against #Sepsis by inhibiting S100a8/a9- mediated neutrophil infiltration and #SystemicInflammation, underscoring its potential as a #TherapeuticTarget.

#OpenAccess: doi.org/10.1038/s413...

#Plasma resuscitation reduced #systemicinflammation vs #balancedsaltsolution after induced low-dose #LPS #endotoxaemia but did not affect #glycocalyx degradation

www.bjanaesthesia.org/article/S0007-0912(25)00...

Perturbation: The Repetitive Trauma of Shift Work Perturbation (noun): a disturbance of motion, course, arrangement, or state of equilibrium.Shift work isn’t one great trauma. It’s thousands of small ones. A kind of repetition injury—biological, not ...

www.nursewhowrites.com/post/perturb...
#ShiftWorkersParadox #CircadianHealth #BiologicalTrauma #ChronicPerturbation #InflammationCycle #NightShiftScience #OccupationalHealth #MetabolicDisruption #SleepDeprivationScience #NurseWhoWrites #EndothelialHealth
#SystemicInflammation #ScienceAndStory

Higher Systemic Immune-Inflammation Index is associated with non-alcoholic fatty liver disease; Hedge’s g = 0.11 and odds ratio (OR) = 1.45. Further longitudinal studies are needed. #NAFLD #SII #SystemicInflammation #Biomarker #MetaAnalysis journals.lww.com/annals-of-me...

High consumption of ultra-processed foods linked to systemic inflammation – BioNews Central Higher consumption of ultra-processed foods is linked to significantly elevated high-sensitivity C‑reactive protein, a marker of inflammation and predictor of cardiovascular disease. ...

Higher consumption of #UltraProcessedFoods is linked to significantly elevated high-sensitivity #CReactiveProtein, a marker of #inflammation and predictor of #CardiovascularDisease. 
#SystemicInflammation

#Cirrhosis
#LiverDisease
#PortalHypertension
#SystemicInflammation
#Biomarkers

Regular Flossing Tied to Reduced Ischemic Stroke Risk Regular tooth flossing is tied to a lower risk for ischemic stroke, primarily by reducing systemic inflammation, which can lead to AF, and up the risk for a cardiometabolic event.

www.medscape.com/viewarticle/...

#Flossing and #Stroke association via #SystemicInflammation
#SharedFacts #HealthScience

#CausalityCrisis

4k words added to a chapter on #T2DM written today (will need editing).
Simplified summary - diabetes is all about oral biology/health.
#GumDisease
#Periodontitis
#Pgingivalis
#InsulinResitance
#SystemicInflammation
#OralBacteriaBloodstreamTranslocation
#InsulinReceptorDamage
#Epigenetics