Highly efficient gene knockout in tumor-infiltrating lymphocytes by adenine base editing The disruption of immune checkpoints in T cells is a promising tool for improving the efficacy of tumor-infiltrating lymphocyte (TIL) therapy. While C…

📲𝐍𝐄𝐖 study shows that #adenine base #editing (ABE) can safely and efficiently reprogram tumor-infiltrating #lymphocytes (TILs) to better attack #cancer.

🔗 Read more: www.sciencedirect.com/science/arti...

#CRISPR-Cas9 #ABE #TILs

Tumor-Infiltrating Lymphocytes (TILs): How Our Immune System Enters the Fight Against Cancer

oncodaily.com/oncolibrary/...

#OncoDaily #Oncology #Cancer #Health #Medicine #MedEd #MedOnc #MedNews #TILs

γδ T cells are the prime antitumoral T cells in pediatric neuroblastoma High-risk pediatric neuroblastoma patients have a dismal survival rate despite intensive treatment regimens. New treatment options are thus required. Even though HLA expression in neuroblastoma is low...

our study on #gdTcells in pediatric neuroblastoma is out! In contrast to adult tumors, it is the gdTcells that not only expand, but that are the most tumor reactive #TILs.

#immunology #tumorimmunology

funded by KIKA, Sanquin and supported by Oncode

www.life-science-alliance.org/content/8/11...

Ready for tomorrow's TILS course. Thanks to Sharon and Mark for setting up and running the course tomorrow. #TILS

View presentations on recent studies and approvals of cellular therapies for solid tumors. Join us on June 27 for an expert-led cancer #immunotherapy program, ACI: A Focus on Cellular Therapies, T cell Engagers and TIL Therapies: https://www.sitcancer.org/education/aci/cell-therapies

View presentations on recent studies and approvals of cellular therapies for solid tumors. Join us on June 27 for an expert-led cancer #immunotherapy program, ACI: A Focus on Cellular Therapies, T cell Engagers and TIL Therapies: www.sitcancer.org/education/ac...

@jasonlukemd.bsky.social #TILs 🧪

#ESMOBreast25: Low baseline tumour infiltrating lymphocytes #TILs and nodal involvement may predict #BreastCancer patients with poor prognosis despite pathological complete response to neoadjuvant chemotherapy.

#ESMODailyReporter has more

🔗 buff.ly/YmxaCJ7

This long-term analysis of the ShortHER trial (10-year data, 866 pts) highlights the crucial role of tumor-infiltrating lymphocytes #TILs in ERBB2-positive early breast cancer.

@jama.com @bccroc.bsky.social

#Onco404 #Cancer #Kanser #BreastCancer #MemeKanseri #ERBB2 #HER2 #MedSky #OncSky

SciTech Chronicles. . . . . . . . .May 3rd, 2025 From the lab to the street,trust in science not deceit.. Vol II No 27 339 links Curated Mission Control RSS Feed Vol II No. 2 Wordpress ...

SciTech Chronicles. . . . . . . . .May 3rd, 2025

bit.ly/stc050325

#LEVA #multi-terrain #"Euro-type cargo" #RIVR #"Cosmic inflation" #"102 Infrared Colors" #astrophysics #exposure #Kuiper #infrared #arXiv #"Solar System's Plane" #CRISPR/Cas9 #stage IV" #CISH #TILS #microelectromechanical #DSP #39cc

A huge thank you to Sharon and all the course contributors and leaders today for a great TILS course.
Well done. #TILS

Post lunch pelvic binders #TILS

#TILS continues #education

#TILS

And we're off.....our first ever #TILS course. Massive well done to our Lead Nurse, Sharon for all her hard work paying off. #education

Unlocking the potential of engineered immune cell therapy for solid tumors - Nature Communications Adoptive cell therapy has emerged as a promising approach for treating advanced solid malignancies. Genetic engineering techniques represent an exciting area of research for the development of cellula...

Terrific #ImmunoEngineering #AdoptiveTcellTherapy #Tcells Update from @vicalbarran.bsky.social et al at @nature.com communications | OPEN ACCESS | Online Now | #CARTcells | #TILs | #TCR | #immunotherapy | #immunoncology |

www.nature.com/articles/s41...

#TextoAlternativo Descrição das 8 fotos sequenciadas: Nas quatro primeiras fotos coloridas, ao fundo há uma jardineira vertical com plantas variadas. No centro, está Alan, um jovem de pele branca, cabelo preto com gel e barba preta. Ele está em pé, vestindo uma camisa preta com a frase estampada em branco: "Lute como um surdo!".

Na segunda foto, com uma parede cinza de fundo, Fabi Valente, de pele branca, e magra, sorri alegremente. Ela tem cabelo preto, liso e comprido, e está usando uma camisa preta baby look com a frase em branco: "Lute como uma surda!".

Na terceira foto, também com uma parede cinza ao fundo, Marcela Dutra, de pele negra, usa óculos pretos redondos e sorri para a câmera. Ela tem cabelo encaracolado e comprido e veste uma camisa branca básica com a frase em preto: "Lute como uma surda!".

Na última foto, Alan exibe a lateral do braço esquerdo tatuado com a frase: "Lute como um surdo!".

A CAMPANHA LUTA PELA VISIBILIDADE SURDA!

Este mês é dedicado à visibilidade e à luta pelos direitos dos surdos!
#Legendanacional #LegendaDescritiva #LSE #Acessibilidade #Libras #Surdo #TILS #VisibilidadeSurda

#TILs are not finished yet!

The 35-year-old T cell therapy modality could find its way in cancer therapy, between #CARTCells and immune checkpoint inhibitors that stole the show but have clear limitations.

t.co/F5gt0CLwjm