#ERStress activates IRE1α–XBP1s to upregulate hIAPP transcription via an ACGT site, driving β-cell dysfunction in #type2diabetesmellitus (#T2DM); blocking #XBP1 splicing with MKC3946 lowers IAPP and improves β-cell survival.
#OpenAccess: doi.org/10.1016/j.ge...

Prevalence and Risk Factors of Stroke in Inpatients with Type 2 Diabetes Mellitus in China

A cross-sectional study identified a 13.1% stroke prevalence among #Type2DiabetesMellitus Chinese patients, showing that age, #Hypertension, diabetic duration, and #DiabeticNephropathy are significant independent risk factors.
Read: doi.org/10.1007/s115...

Oral #SodiumNitrate alleviates #MASLD and #Type2DiabetesMellitus (T2DM)-like phenotypes in mice by rebalancing #macrophage polarization via a sialin–CtsL–Nrf2 pathway, reducing #inflammation and metabolic dysfunction. #MetabolicSyndrome

#OpenAccess #STTT: doi.org/10.1038/s413...

Prevalence and Risk Factors of Stroke in Inpatients with Type 2 Diabetes Mellitus in China - Current Medical Science Objective The prevalence and the cluster characteristics of risk factors of stroke were assessed in a Chinese diabetic population. Methods Clinical data of 30 693 inpatients who were diagnosed with…

This study highlights a high prevalence of #Stroke among #Type2DiabetesMellitus patients in China, emphasizing the importance of analyzing clustered risk factors and refining risk identification strategies for high-risk groups. #medsky

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This study reveals the potential of miR-146b as a #diagnosticbiomarker for #type2diabetesmellitus (T2DM) risk in adults with #obesity and suggests that the miR-146b/Btg2 axis may facilitate new T2DM prevention and management strategies. #medsky

#OpenAccess: