#TGFβ1 #MRTFA #VocalFold

👤VF myofibroblast -/+TGFβ1
▶️activated SRF miR-29 GATA1
▶️fibro-contractile phenotype

SRF MRTFA ⏫in injured🐭VF epithelium+mesenchyme

CCG-257081 (MRTFAi)⏬🐭VF scarring
⏬epithelial thickening ⏬GAG ⏫fibrosis

#MatrixBiol 2025
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