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Hashtag
#Wnt2
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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
1 month ago
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Recombinant #Wnt2 protects against #IschemiaReperfusionInjury by promoting Lrp6/Trim11-mediated Nap1L1 degradation, restoring antioxidant gene expression, reducing #ROS, and limiting #cardiomyocyte #apoptosis and #ferroptosis. @FudanUniversity

#STTT: doi.org/10.1038/s413...

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Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
@sigtrans-sttt.bsky.social
3 months ago
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#Wnt2 levels fall after #MyocardialReperfusion, while recombinant Wnt2 protects the #heart from #IschemiaReperfusionInjury by lowering #ROS and preventing cell death through Lrp6/Trim11‑mediated Nap1L1 degradation. @fudan-university.bsky.social

#STTT: doi.org/10.1038/s413...

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