Supercoiling not only brings DNA to life (and makes it dance) but also changes how key proteins such as #CRISPR interact with it. Thanks @qmsmith.bsky.social for the brilliant collaboration, Sylvia for developing an amazing new #imageanalysis pipeline & @eddierollins.bsky.social for beautiful #AFM.
1/11 In our story out today in @nature.com , we showcase the molecular mechanisms that enable Cas9 to bind and cleave negatively supercoiled ((-)SC) off-targets! 🧬🧵
🔗 www.nature.com/articles/s41...
#CRISPR #Cas9 #DNATopology #AFM #CryoEM #SingleMolecule #Biophysics
A silver package closed with two screws.
Open package with ten slots for tips. Each tip is secured with an individual screw.
When loosening the screw, the clamp holding down the tip is moved into a small groove next to the tip
Lab bling-bling... We currently have a training for our new Raman-AFM and I am absolutely stunned by the packaging of our new TERS #AFM tips. The case is really heavy and looks like an expensive case for jewellery 😍. #microscopy
🧪🔬👩🔬
#fcsp
Funktioniert bei eich das AFM Radio?
Sitz im Zug aber bekomme ausser der Werbung keinen Ton 🥲
#Afm #fcspsge
Nog maar eens:
Het advies van #CPB #DNB #AFM is om de #hypotheekrenteaftrek af te schaffen.
Maar vermogenden van de @vvdonline.bsky.social houden dat tegen.
Misschien toch eens onderzoeken #overgangsregeling?
digitalekrant.trouw.nl/trouw/2725/a...
Happy 4️⃣0️⃣ birthday #AFM! 🥳🎂 It was a real pleasure to host Christoph Gerber in 2023 🤗
Happy Birthday #AFM!
To celebrate the first description of the atomic force microscope (AFM) in Physical Review Letters, we spoke to our longstanding honorary member Christoph Gerber, who, together with Carl Quate and Gerd Binnig, invented this groundbreaking instrument.
@unibas.ch bit.ly/4raqCOm
José Pérez Berdud, presidente de la Asociación de Fabricantes de Máquinas-Herramienta, AFM
📖 Cuaderno #Máquina-Herramienta 2026 de @estrategiaempre.bsky.social
“Nuestra base industrial y tecnológica permite afrontar el futuro con confianza”, #JoséPérezBerdud, presidente de la Asociación de #Fabricantes de #Máquinas-Herramienta, #AFM
tinyurl.com/3muu6eu5
Since I moved to Instagram, I've been missing discussions with a lot of people. That is why I decided to put the most permanent content also on YouTube. Behold! Please share to grow the community. #AFM #Science #Microscopy
youtube.com/@hectorvsthe...
🤔 Are the physics of CR-AFM more complex than we thought? By tracking ultra-high frequency thermal oscillations, Philip Egberts and team found that existing models fail to match experimental data across various tip–sample combinations.
➡️ https://tinyurl.com/3vmet3pv
#AFM #SurfaceScience #BJNANO 💎🔓
VEB wil onderzoek naar verspreiding overnamenieuws InPost
www.transport-online.nl/118657/veb-w... #AFM #InPost #overname #VEB #FedEX #Advent
Don't miss out on Subgroup Saturday at #BPS2026! We are excited to be a sponsor of "Single-Molecule Forces, Manipulation, and Visualization" (AM) and "Nanoscale Approaches to Biology" (PM). See you in the symposia!
#biophysics #single-molecule #AFM #spectroscopy #nanoscale
It's a good week 🥰: my morning started again in the lab, this time measuring redox active organic layers attached to our rare earth oxides using one of our atomic force microscopes. In between, I gave a lecture on " #Microscopy in #Battery Research" for the local graduate school. I ♥️🔬!
#AFM
www.instagram.com/reel/DUYeLER...
🛑 Niet iedereen mag financieel advies geven!
In deze nieuwe Moneytalk-serie legt Judith Sanders van ABN AMRO uit hoe je kunt checken of een finfluencer eigenlijk wel de juiste papieren heeft om advies te geven.
#finfluencers #AFM #moneytok #BeleggerUitlegger
Black Instrument with laser warning signs and more devices in the background
Meet our newest baby: our Raman-AFM was set up today. We can now perform #AFM and Raman spectroscopy at the same spot and also carry out TERS (tip enhanced Raman spectroscopy) analyses 😍.
🔋🧪🔬 #ChemSky
rare don" care February Rare Disease Awareness Month (RAREDISEASEMONTH | FEBRUARY2026 ) SRNA connect. care. cure.™
Siegel Rare Neuroimmune Association - The non-profit advocating for those those with ADEM, AFM, MOGAD, NMOSD, ON, and TM! Having a rare disease is not easy. It is so much more than just a diagnosis. Finding support is difficult because not many people share the same diagnosis. The unanswered questions. The lack of experts close by. The psychological and emotional challenges. And the list goes on. Over 300 million people worldwide live with a rare disease. 28 February is Rare Disease Day, and since 2020, we at SRNA have decided to make the whole month of February "SRNA's Rare Disease Month" because awareness of rare diseases should not be limited to just one day of the year. We will be sharing stories, resources, facts, and helpful tips during the entire month of February. Join us this month to share facts, your personal story, and raise awareness about your rare disorder!
Goedemorgen! ✨ 28 februari is #RareDiseaseDay, maar heel februari is SRNA’s #RareDiseaseAwarenessMonth, omdat bewustwording van zeldzame ziekten niet beperkt mag zijn tot slechts één dag van het jaar. ❤️🔥💪
#ADEM #AFM #MOGAD #NMOSD #ON #TM &
Hoffe, das lief angenehm ab, die Übernahme vom Klub. Bei der #AFM gab's ja schon öfter Chefchen, die in die Motivation toller Menschen reinregiert haben...
Less than one week to apply to this 2.5 yr PDRA!
If you're passionate about biophysics #AFM #Microscopy applied to bacteria and #antimicrobial research this will be a great opportunity in the beautiful city of Sheffield. 😀
jobsite.sheffield.ac.uk/job/Research...
What a milestone for the field of Fluidic Force Microscopy. Seeing OUR technology recognized with a
@natrevmethodsprimers.nature.com is a testament to its growing impact on #singlecell manipulation and nanotechnology. Congrats! @ethz.ch @ucdavis.bsky.social #HUNREN
#FluidFM #SameCell #AFM
An AFM phase shift image of a block copolymer exhibiting an intricate Turing pattern.
I was happy to contribute a small piece to the puzzle with performing #AFM measurements on block copolymer-based electrolytes to determine the width and distribution of the two different polymer phases. 2/2 #battchat
“Internetkenner en autonomie-activist Bert Hubert, die al jaren aandacht vraagt voor zogenoemde digitale autonomie, is blij met de aandacht, maar: "Het is ook wel belachelijk laat. Dit is al vijf jaar aan de gang" #BigTech #DigiD #Belastingdienst #SVB #AFM #Microsoft #formatie
nos.nl/artikel/2599...
