Colchicine for Atherosclerotic Cardiovascular Disease Prevention TH: Why did you (and your colleagues) write this paper? What was its main purpose? AIMÉE M.H.

Read our interview 🗣️with the lead authors Aimée M.H. van Zelm and Noel C. Chan on their 🆕 article on #Colchicine for #Atherosclerotic Cardiovascular Disease Prevention

👀Read Full text article here 🔗 www.thieme-connect.com/products/ejo...

www.linkedin.com/pulse/colchi...

Repurposing “Bad Cholesterol” to Precisely Target Inflammation in Atherosclerosis Professor Lisa Volpatti developed a targeted approach that directs anti-inflammatory proteins to diseased arteries, reducing immune cell activity and improving therapeutic effectiveness.

Targeted delivery that directs #IL-10 to #atherosclerotic #plaques with precision, modulates #inflammatory pathways. bit.ly/3ZgeUq5 go.nature.com/3OoyNsy

P. gingivalis in #Atherosclerotic plaques exacerbates plaque instability by disrupting the FOXO3-HDAC2 axis, driving #OxidativeStress-mediated macrophage #Necroptosis, thus establishing a causative link between periodontal health and #ASCVD.

#OpenAccess: doi.org/10.1038/s413...

Time trends in mortality from heart failure and atherosclerotic cardiovascular disease in people with and without diabetes: a multi-national population-based study Declines in heart failure mortality in both people with and without diabetes were less marked than were declines in CHD and cerebrovascular disease mortality in most jurisdictions. Heart failure morta...

Current efforts to manage diabetes appear to have narrowed the gap between people with and without #diabetes in terms of #atherosclerotic #CVD mortality, but not in terms of #heart failure mortality thelancet.com/journals/lan...
#T2D #heartfailure

#MedSky #EndoSky #CardioSky

DT-109 significantly reduces #atherosclerotic lesions and #VascularCalcification in #primates by downregulating #inflammation and #osteogenic markers, highlighting DT-109 as a promising therapy for #CardiovascularDisease.

#OpenAccess in #STTT: doi.org/10.1038/s413...

Time trends in mortality from heart failure and atherosclerotic cardiovascular disease in people with and without diabetes: a multi-national population-based study Declines in heart failure mortality in both people with and without diabetes were less marked than were declines in CHD and cerebrovascular disease mortality in most jurisdictions. Heart failure morta...

In four of seven jurisdictions with #heartfailure data available, declines in heart failure mortality were less marked than declines in mortality due to #atherosclerotic #cardiovascular disease in people with & without #diabetes www.thelancet.com/journals/lan... #ASCVD

#MedSky #EndoSky #CardioSky

Health-related quality of life among people with #HIV at low-to-moderate risk for #atherosclerotic cardiovascular disease in the REPRIEVE Trial journals.lww.com/aidsonline/a... #hvhebron #malinf @aidsjournal.bsky.social

Current efforts to manage #diabetes appear to have narrowed the gap between people with and without diabetes in terms of
#atherosclerotic #cardiovascular disease mortality, but not in terms of heart failure mortality www.thelancet.com/journals/lan...
#T2D #heartfailure #ASCVD

#EndoSky #CardioSky

Recent advances in research and care of familial hypercholesterolaemia Heterozygous familial hypercholesterolaemia is a common, autosomal semi-dominant condition characterised by elevation of LDL cholesterol from birth and early onset of atherosclerotic cardiovascular di...

Heterozygous familial #hypercholesterolaemia is a common, autosomal semi-dominant condition characterised by elevation of #LDL #cholesterol from birth and early onset of #atherosclerotic #cardiovascular disease www.thelancet.com/journals/lan...
#HeFH #ASCVD

#MedSky #EndoSky #CardioSky

Time trends in mortality from heart failure and atherosclerotic cardiovascular disease in people with and without diabetes: a multi-national population-based study Declines in heart failure mortality in both people with and without diabetes were less marked than were declines in CHD and cerebrovascular disease mortality in most jurisdictions. Heart failure morta...

New—Time trends in mortality from heart failure and #atherosclerotic #cardiovascular disease in people with and without #diabetes: a multi-national population-based study thelancet.com/journals/lan...
#HeartFailure #ASCVD #T2D

#MedSky #EndoSky #CardioSky

Porphyromonas gingivalis infection exacerbates #Atherosclerotic plaque destabilization by promoting #OxidativeStress-mediated #necroptosis in lipid-laden macrophages via upregulating MSR1 expression. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

Porphyromonas gingivalis infection exacerbates #Atherosclerotic plaque destabilization by promoting #OxidativeStress-mediated #necroptosis in lipid-laden macrophages via upregulating MSR1 expression. #medsky

#STTT #OpenAccess: doi.org/10.1038/s413...

Glycine-based #tripeptide DT-109 reduces aortic and #coronary #atherosclerotic lesions and ameliorates #calcification in a nonhuman #PrimateModel, positioning it as a novel therapeutic agent for #CardiovascularDiseases. #medsky

Read in #STTT #OpenAccess: doi.org/10.1038/s413...

#Medsky🧪 #IDsky #virosky #Immunosky #episky #Cardiosky #publichealth @jama.com #Influenza is associated with an increased risk of adverse cardiovascular events, including #atherosclerotic events, #heartfailure
events & #atrialfibrillation

Evaluation of Lipoprotein(a) as a Prognostic Marker of Extracoronary Atherosclerotic Vascular Disease Progression | Circulation BACKGROUND: Despite current treatment strategies for atherosclerotic vascular disease focusing on lifestyle modification and lowering cholesterol, a significant residual risk of major atherosclerotic ...

Concentraciones elevadas de lipoproteína (a) se asocian con enfermedad vascular aterosclerótica extracoronaria y progresión a complicaciones mayores #Lpa #atherosclerotic www.ahajournals.org/doi/10.1161/...

The April issue is now online!

👉 Read our latest articles!

🔗 onlinelibrary.wiley.com/toc/13652796/2025/297/4

#statin #glomerular #lungtransplantation #cardiovascular #rheumatoid #anticoagulants #atherosclerotic #neuroimaging #cognitive #diabetes #biosensors #delirium

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Artificial Sweetener Raises Heart Disease Risk: #Aspartame increases risk of #heart disease by triggering #insulin spikes that lead to artery-clogging #atherosclerotic #plaques
www.instagram.com/p/DGyCI-ZOjLW/

Joint association of #physicalactivity and night #sleep duration with the risk of #atherosclerotic #cardiovascular disease

Engaging in sufficient PA can reduce the risk of ASCVD in individuals with short sleep duration.
www.sciencedirect.com/science/arti...

Pilot Study of Using #MachineLearning to Detect #Atherosclerotic Renal Artery #Stenosis from Spectral #Doppler Waveforms

#VisualAbstract by @hellokidneyMD

www.kireports.org/ar...

We review preclinical and clinical findings that demonstrate how #sleep influences the autonomic nervous, #metabolic and #immune systems to affect #atherosclerotic #cardiovascular disease.
www.nature.com/articles/s44...