Frenster Lab | Cell Competition Dynamics We study Cell Competition during Embryonic Development using 3D Gastruloids at the University of Freiburg. We view cells as interactive societies in development and cancer. Research, stem cells, Gastr...

The Frenster Lab is here! 🍾 I am so excited to start my #EmmyNoether funded group at @uni-freiburg.de this summer. Our group studies #CellCompetition dynamics during embryonic development using #gastruloids from multiple species. Thanks to the @dfg.de for creating this opportunity! FrensterLab.com

Drawing showing how mechanical forces shape cell competition and elimination at tissue boundaries.

Cells compete to maintain tissue health. A #research team from #MPZPM, @ijmonod.bsky.social & #NielsBohrInstitute found that force transmission decides the winner, challenging classical #CellCompetition views.

Learn more 👉 mpzpm.mpg.de/news/news-de...

#science #cellbiology

📸 Lucas Anger

1/3 Embryogenesis requires fit cells. Here, following work from @miguel-torres-1963.bsky.social & @tristanrodriguez72.bsky.social and led by @joshifrenster.bsky.social we develop a #gastruloid model of #CellCompetition
www.biorxiv.org/content/10.1...
showing it recapitulates much of the embryo 🧵

Foxo3-mediated physiological cell competition ensures robust tissue patterning throughout vertebrate development - Nature Communications Physiological roles of cell competition in vertebrates and the universal mechanisms regulating diverse cell competition are unknown. Here, authors show that Foxo3-mediated physiological cell competiti...

EXCITED to share our new paper in Nat Commun @natureportfolio.bsky.social "Foxo3-mediated physiological cell competition ensures robust tissue patterning throughout vertebrate development”, identifying a potential marker of cell competition. #zebrafish #cellcompetition
www.nature.com/articles/s41...

Ever wonder how cells in our epithelia fight for space? 🤔

Let's dive into the fascinating world of mechanical cell competition! #EpithelialMechanics

Hello, I am @akshar21.bsky.social and I'll be your guide through this thread on mechanical #CellCompetition

Landmark revisit
#Angiogenesis #CellCompetition VEGFR1/2 NOTCH

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

#NatureCellBio 2010
www.nature.com/articles/ncb...