Ribosome biogenesis and homeostasis: in the front line to cope with cellular stress Cells must continuously adapt to both internal and environmental stresses by finely tuning their molecular and metabolic activities. One of the most r…

Fascinated by how cells adapt to a plethora of stimuli?

​This review describes how cells use and modulate #ribosomes to cope with stresses. We discuss the central role of ribosome-associated processes in #cellplasticity, #signaling, #geneexpression and #diseases 🕹

@cbitoulouse.bsky.social

The Trojan Horse Within: Mechanisms of Immune Evasion in Breast Cancer The Trojan Horse Within: Mechanisms of Immune Evasion in Breast Cancer

📢 We review the mechanisms of immune evasion in breast cancer, focusing on how cellular plasticity and the tumor immune microenvironment cooperate to suppress detection. 🧬
@chp-pivot.bsky.social
www.pivotscipub.com/chp/3/1/0001...
#breastcancer #ImmuneEvasion #TumorMicroenvironment #CellPlasticity

Postdoctoral Researcher in "Cancer Neuroscience: the impact of neural activity on 3D genome organization and cellular plasticity in glioblastoma”

Excited to share I’ve received a #SSMF #Consolidator grant!

📣 Recruiting a #postdoc to study #cancer #neuroscience #3Dgenomics #multiomics #singlecellomics

🔬How neural inputs shape #3Dgenome and #cellplasticity in #glioblastoma #GBM

Interested? Apply now 👇
rb.gy/m7xz7b

A plastic EMP1⁺ to LGR5⁺ cell state conversion as a bypass to KRAS-G12D pharmacological inhibition in metastatic colorectal cancer Abstract. Inhibitors of the oncogene KRAS hold promise for treating metastatic CRC (mCRC). Here we show that a selective, covalent small molecule inhibitor of the active (ON) conformation of RAS-G12D,...

Cell plasticity as a mechanism to evade KRAS inhibition in colorectal cancer.

#KRAS #CellPlasticity #CancerStemCell 🧪

If you’re interested in liver regeneration, cholangiocyte biology, or cell fate plasticity, we’d love to hear your thoughts!

#LiverRegeneration #Zebrafish #RegenerativeBiology #CellPlasticity
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If you enjoyed our @naturegenet.bsky.social paper on how PROX1 safeguards hepatocyte identity, check out the behind-the-scenes Research Briefing—both free to read:
Paper: rdcu.be/d9IFg
Briefing: rdcu.be/eaLYL
#CellPlasticity #CancerResearch

Epigenetics Update - Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis go.nature.com/3QilEiM

Judith B. Zaugg and Moritz Mall reporting in Nature Genetics

#Epigenetics #CellPlasticity
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Empower your research with epigenome.us

Great time and fun science discussion with my former PhD mentor and our invited speaker Prof Riccardo Fodde @labriccardofodde.bsky.social #cellplasticity in CRC

We love welcoming back our alumni! Jordi Casanova (@IRBBarcelona), hosted by Ernesto Sánchez-Herreros, has delivered a seminar today on #cellplasticity and #autophagy. He completed his PhD at Ginés Morata’s lab 🪰