The m6A regulator KIAA1429 stabilizes RAB27B mRNA and promotes the progression of chronic myeloid leukemia and resistance to targeted therapy

KIAA1429-driven m6A modification promotes #ChronicMyeloidLeukemia progression and imatinib resistance via the m6A/YTHDF1–RAB27B axis, while #rucaparib suppresses KIAA1429, reduces #TumorGrowth, and enhances imatinib sensitivity.
#OpenAccess: doi.org/10.1016/j.ge...

Welcome! You are invited to join a webinar: Max Insights: 25 Years of CML Treatment Innovation. After registering, you will receive a confirmation email about joining the webinar. Join us as we mark 25 years of innovation in chronic myeloid leukemia (CML) treatment and reflect on the breakthroughs that have transformed patient outcomes and access to life-extending medicines.…

Sign up now➡️https://buff.ly/gFvhVNB

@patggmax.bsky.social
#CancerInnovation #ChronicMyeloidLeukemia #CancerTreatment #TheMaxFoundation

We're grateful to work alongside the dedicated Black Lion Hospital team. Together, we continue to bring healing and renewed hope to the CML community in Ethiopia. 💙

#WorkingTogether #HealthEquity #PartnershipInAction #chronicmyeloidleukemia #PatientCare #CancerHope #TheMaxFoundation

This review explores how the #UbiquitinProteasomeSystem regulates BCR-ABL signaling, #leukemia stem-cell survival, and drug response in #ChronicMyeloidLeukemia, highlighting UPS targets to overcome #TKI resistance & improve outcomes. @zzu_china

#OpenAccess: doi.org/10.1016/j.ge...

Imatinib Tablets IP 400 mg plays an essential role in managing abnormal cell growth that occurs in chronic myeloid leukemia. It is a medication that seeks to eliminate cancer-causing agents, thereby helping in the management of diseases. However, it has a significant role in the management of chronic myeloid leukemia, which can be explained by How Imatinib Tablets IP 400 mg Help Manage Chronic Myeloid Leukemia. It is available by Oddway International in the markets of Russia, USA, and the UK while referring to both B2B and B2C requirements.

How Imatinib Tablets IP 400 mg Help Manage Chronic Myeloid Leukemia - Oddway

quickbloging.com/how-imatinib...

#ImatinibTabletsIP400mg #ImatinibTablets #ChronicMyeloidLeukemia #CMLTreatment

As we step into 2026, let’s carry his words with us:
“Keep rocking and enjoy life as much as possible!" 💙

Here’s to a year of strength and unforgettable adventures! 🎉

buff.ly/glA8mms

#NewYearNewHope #ChronicMyeloidLeukemia #PatientStories #TheMaxFoundation

Treatment-Free Remission after TKIs Is Feasible Among Patients with CML in Low-Income Countries | Blood Cancers Today In a study of patients with CML in low- and middle-income countries who received TKIs, most patients remained relapse-free after a follow-up of 6 months or more.

Treatment-free life is now an option for eligible patients. A huge step forward!

Thanks to our local partners for collaborating on patient-centered care 🙏🏾

Read more about TFR for LMICs: buff.ly/cLes0Ub

#TreatmentFreeRemission #ChronicMyeloidLeukemia #HealthEquity #AccessToCare #TheMaxFoundation

Patients With CML Living in LMICs May Reach High TFR Rates - Oncology Nurse Advisor Researchers evaluated long-term outcomes among patients with CML living in LMICs who received imatinib through financial assistance from the Max Foundation.

Treatment-free relapse is a feasible target for patients with #chronicMyeloidLeukemia living in low- and middle-income countries. Presented at #ESMO25, from @hematologyadvisor.bsky.social.

https://bit.ly/4ppEsMq

#CML #leusm

Today, Leona is a proud grandmother, a dancer, and a volleyball player. 🏐 Her story reminds us that behind every diagnosis is a person with dreams.💙

buff.ly/GoK80oo

#TreatmentFreeRemission #ChronicMyeloidLeukemia #TheMaxFoundation #GlobalHealth #PatientStories

Today we celebrate the resilience of people living with #ChronicMyeloidLeukemia (CML), and the progress that’s changing lives around the world.

Living with CML doesn’t mean giving up on life—it means living it as vibrantly as ever. 🌟

buff.ly/r8DfVyA

#WorldMotorcycleDay #ChronicMyeloidLeukemia #ChaiForCancer #MotorcycleLife #TheMaxFoundation #NotJustSurvivingButThriving

KIAA1429 is highly expressed in #ChronicMyeloidLeukemia (CML) blast crisis (BC) and enhances RAB27B mRNA stability, upregulating its expression through the KIAA1429/m6A/YTHDF1 axis, ultimately driving CML progression. #m6AModification #medsky
#OpenAccess:
buff.ly/H5PEexz

Researchers performed multi-level #SingleCellSequencing to identify the expansion and diversity of T cell subsets in #ChronicMyeloidLeukemia (CML) and demonstrated the potential communication between non-immune cells and T cell subsets in the #bonemarrowmicroenvironment. #medsky

: buff.ly/wBPIC6I

KIAA1429 is highly expressed in #ChronicMyeloidLeukemia (CML) blast crisis (BC) and enhances RAB27B mRNA stability, upregulating its expression through the KIAA1429/m6A/YTHDF1 axis, , ultimately driving CML progression. #m6AModification #medsky

Happy birthday to Brian J. Druker! He won a 2009 #LaskerAward for the development of molecularly-targeted treatments for #chronicmyeloidleukemia, converting a fatal cancer into a manageable chronic condition. @ohsunews.bsky.social
#NationalCancerControlMonth buff.ly/3Q9wYxA

Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow microenvironment of chronic myeloid leukemia

Researchers performed multi-level #SingleCellSequencing to identify the expansion and diversity of T cell subsets in #ChronicMyeloidLeukemia (CML) and demonstrated the potential communication between non-immune cells and T cell subsets in the #bonemarrowmicroenvironment. #medsky

buff.ly/vUTdPhk

Digital PCR Can Determine If Chronic Myeloid Leukemia Patients in Remission Can Stop Drug Treatment Novel study in Elsevier’s Journal of Molecular Diagnostics shows that BCR::ABL1 digital PCR is more sensitive, accurate than real-time quantitative PCR

Novel study in @jmdiagn.bsky.social shows that #digitalPCR can reliably identify which #chronicmyeloidleukemia patients in remission can successfully discontinue drug treatment. A reliable tool to aid clinical decision-making. @elsevierconnect.bsky.social

spkl.io/6011fQKkd

Review Series on a Quarter Century of TKIs in CML Podcast Episode · Blood Podcast · S9 Bonus · 33m

Congrats to Dr. Jason Gotlib, Stanford #Hematology on this podcast celebrating 25yrs of TKIs to treat #chronicmyeloidleukemia
A triumph of medical science highlighting the importance of lab & clinical research @stanforddeptmed.bsky.social
@ash.hematology.org
podcasts.apple.com/us/podcast/b...

#Leukemia, #CML, #BloodCancer, #CancerAwareness, #LeukemiaAwareness, #ChronicMyeloidLeukemia, #Hematology, #Oncology, #BloodDisorders, #CancerResearch, #LeukemiaSupport, #CancerTreatment, #MyeloidLeukemia, #LeukemiaPatients, #BloodCancerAwareness, #CancerFight, #LeukemiaJourney, #CancerSurvivor,

FDA Approves Generic Nilotinib: Expanding Access to Chronic Myeloid Leukemia Treatment - OncoDaily FDA Approves Generic Nilotinib: Expanding Access to Chronic Myeloid Leukemia Treatment / Access to Oncology Medicines Coalition, cancer, chronic myeloid

FDA Approves Generic Nilotinib: Expanding Access to Chronic Myeloid Leukemia Treatment
@fda.gov

oncodaily.com/drugs/niloti...

#AccessToOncology #MedicinesCoalition #Cancer #Medicine #ChronicMyeloidLeukemia #CML #CMLTreatment #FDA #Health #Nilotinib #OncoDaily #Oncology #UICC #TheMaxFoundation

I was diagnosed with #ChronicMyeloidLeukemia this year. My treatment, Dasatanib, costs $40,000/month here but only $120/month in India. Are we really still confused about why prices are skyrocketing? It’s pure greed. The elite profit while Americans struggle. #EatTheRich #DenyDefendDepose

Chronic Myeloid Leukemia Treatment in India - A type of cancer that affects the blood and bone marrow.

Read more:- youtube.com/watch?v=zvsq...

#ChronicMyeloidLeukemia #CML #leukemia #CancerTreatment #IndiaHealthcare #MedicalTourism