Cedars-Sinai Heart Scientists Earn Top National Honors
www.newswise.com/articles/ced...
#AmericanHeartAssociation #heartscientists #nationalhonors #smidtheartinstitute #CellTherapy #humanheartcells #clinicalproteomics #proteins #HypertensionResearch #pregnancyhypertension #preeclampsia #stroke
#USHUPO #proteomics #precisionmedicine #biomarkerdiscovery #therapeutictargets #singlecellproteomics #spatialproteomics #clinicalproteomics
#USHUPO #proteomics #singlecellproteomics #spatialproteomics #clinicalproteomics #therapeutictargets
71 proteins were always found in the blood, including 22 already used in medicine!
This shows MS can be used for clinical research. #massspectrometry #clinicalproteomics #biomarkers #TeamMassSpec
My Mastodon rant using the hashtag #ClinicalProteomics ("Hormone Proproteins & Where To Find Them") is now available in blog essay format.
https://thegpm.org/clinical/
TFF2:p (trefoil factor 2) is an tiny little secreted protein (24-129) that shows up particularly well in urine & stormach. Previously known as "spasmolytic protein 1". Like the other trefoil factors, it is well characterized but poorly understood. #ClinicalProteomics
AGRP:p (agouti related neuropeptide) is a ha'penny protein (21-132) that can loose an nward remnant peptide to form the eponymous hormone (83-132). The observed localization of the protein does not match the 'zine/database banter about what this protein is all about. #ClinicalProteomics
PYY:p (peptide YY) is a tiny proprotein (29-97) produced mainly in the gut that contains the sequence of its namesake hormone (29-64). It slows down the secretion of pancreatic digestive enzymes, reduces gastric motility & increases water and salt absorption by the colon. #ClinicalProteomics
ECRG4::p (ECRG4 augurin precursor) is a small proprotein (32-148) that contains the sequence for the 52 residue peptide hormone Augurin (71-132). The role of the hormone in the brain is a little foggy & its presence in bone seems to be enhanced in some tumours, e.g. chordoma. #ClinicalProteomics
