Unlock novel bioactives - Iain Coldham et la. describe the formation of #spirooxindoles using an intermolecular nitrone #cycloaddition reaction.
🔗 www.beilstein-journals.org/bjoc/articles/21/146
#cascade #oxindoles #spirocycle #stereochemistry
#BJOC 💎🔓

From classical methods to a dynamic kinetic strategy, Wang & co-workers showcase how #aziridines can be activated with precision✨Their radical–polar crossover (4+3) #cycloaddition unlocks diverse azepines & new paths for N-containing targets 🧪
#synpacts

👉 buff.ly/H5aiDLV

Unlocking complex spirocyclic oroidin #alkaloids like palau’amine🔬 Carl Lovely & co-workers report a novel Diels–Alder sequence with tandem #TBAF desilylation, oxidation & rearrangement to create a versatile intermediate for #TotalSynthesis.
#cycloaddition

👉 buff.ly/mi6k9Sl

John Molloy @molloylab.bsky.social et al. at the @mpici.bsky.social and the @freieuniversitaet.bsky.social focus on light-enabled intramolecular [2 + 2]-#cycloaddition via #photoactivation of simple #alkenylboronic #esters: ➡️ https://tinyurl.com/zn36wntr

#BJOC 💎 🔓 @peterseeberger.bsky.social

This study demonstrates a visible-light-induced topochemical #cycloaddition of a bimane derivative. 
➡️ www.beilstein-journals.org/bjoc/articles/21/37
#bimanes #cycloaddition #cyclobutanes. #fluorescence #BJOC 💎🔓
@mathiassenge.bsky.social

Unleash the power of bicyclo[1.1.0]butanes (#BCB)🤯Dive into the advancements in #Lewisacid-catalyzed formal #cycloaddition reactions of BCBs by Yang, Chen and Zhou. Discover efficient strategies for synthesizing complex bicyclic #bioisosteres.
👉 www.thieme-connect.com/products/ejo...