So many children could benefit from #epilepsysurgery - but only 0.5% are referred! Epileptologist Dr. Juan Perez 🤩🇨🇴 explains how lack of knowledge of neurologists - is leading to fewer referrals! Watch👇!
🎬 youtu.be/soYzQgbOdt4
This episode is presented in partnership with EASEE®, by Precisis GmbH.
This case shows the potential of SqEEG to guide treatment decisions in the perioperative setting.
doi.org/10.1002/epi4...
#epilepsy #ILAE #epilepsiaopen #epilepsysurgery #epilepsytreatment #objectiveseizuredocumentation #subcutaneousEEG #ultralongtermEEGmonitoring
Combining MRI and interictal iEEG abnormalities significantly improved outcome differentiation.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #epilepsysurgery #graymatter #iEEG #multimodal #superficialwhitematter
Largest reported series highlighting rare but serious sEEG-related pseudoaneurysms and the need for prompt imaging and treatment.
doi.org/10.1002/epi....
#epilepsy #ILAE #epilepsia #complication #epilepsysurgery #SEEG
SEEG offers a unique framework for prospective white matter functional mapping in epilepsy patients.
doi.org/10.1111/epi....
#epilepsy #ilae #epilepsia #epilepsysurgery #SEEG #whitematter #anatomy
How does the blood-brain barrier influence epilepsy? 🤔🧠 Join Dr. Claire Behan 🤩🇮🇪 & Dr. Chris Greene 🤩🇮🇪 on the podcast to hear all about it as they chat with Torie!👇
🎬 youtu.be/rBpI_-daWjw
#epilepsyawareness #epilepsyresearch #bloodbrainbarrier #epilepsysurgery #epilepsyawarenessmonth
“We have to protect one area of the brain & remove another.” - Dr. Ricardo Morcos 🤩 🇬🇧!
A hopeful, very educational chat about the epilepsy surgery journey 🔪🧠 - clear, empowering, & informative!
Watch the full episode here! 👇
youtu.be/QzIoLlRG1Lw
#epilepsysurgery #epilepsy #neurosurgery
Approx. 30% of people with an epilepsy don’t respond well to meds – so what happens next? 🧠
On #Epilepsy Sparks Insights🎙️, Torie Robinson chats with Dr. Ricardo Morcos 🤩🇬🇧 about the #epilepsysurgery pathway – from EEGs & MRIs to MDT meetings & life after surgery! 👇
🎬 Watch here: youtu.be/QzIoLlRG1
7T magnetic resonance imaging (MRI) detected epileptogenic lesions in 15% of 3T MRI-negative patients with drug-resistant epilepsy.
doi.org/10.1111/epi....
#Epilepsy #ILAE #epilepsia #7T #epilepsysurgery #epileptogeniclesion #UHFMRI
We conducted a translation and back-translation methodology to obtain a Spanish version of the Epilepsy Surgery Satisfaction Questionnaire-19 (ESP-ESSQ_19).
doi.org/10.1111/epi....
#epilepsy #ilae #epilepsia #drugresistantepilepsy #epilepsysurgery #patientsatisfaction #qualityoflife
We developed a two-stage ML framework for FCD detection using surface-based processing of 3D MRF, including 44 FCD patients and 70 healthy controls.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #epilepsysurgery #focalcorticaldysplasia #machinelearning #MRfingerprinting #presurgicalevaluation
Most respondents consider surgery in Lennox–Gastaut Syndrome (LGS) after failure of 3–4 medications and ketogenic diet, later than ILAE-recommended guidelines.
doi.org/10.1002/epi4...
#epilepsy #ILAE #epilepsiaopen #epilepsysurgery #LennoxGastautsyndrome #neuromodulation #surgicaldecisionmaking
In univariate analyses, decreased cortical and subcortical metabolism on FDG-PET was a stronger discriminator of dysplastic cortex than surface-based MRI features.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #artificialintelligence #epilepsysurgery #multimodalneuroimaging #AI
Interictal low-entropy activity marks epileptogenic zones even without visible spikes or seizures in intracranial electroencephalography (iEEG).
doi.org/10.1111/epi....
#epilepsy #epilepsia #ILAE #entropy #epilepsysurgery #interictaldata #intracranialEEG #outcomeprediction
Task-induced high-frequency activity (HFA) is a marker of cortical processing and a promising functional mapping approach for SEEG.
doi.org/10.1111/epi....
#epilepsy #ILAE #Epilepsia #directcorticalstimulation #epilepsysurgery #functionalmapping #highfrequencyactivity #presurgicalevaluation #SEEG
Low Awareness of Epilepsy Surgery: Less than half of included epilepsy patients in Serbia are familiar with epilepsy surgery (ES) for drug-resistant epilepsy (DRE).
doi.org/10.1002/epi4...
#epilepsy #ilae #epilepsiaopen #antiseizuremedications #education #epilepsysurgery #media
Shorter time to epilepsy surgery is associated with higher seizure freedom rates; every 3-month delay from epilepsy diagnosis to surgery reduces the chance of seizure freedom after surgery by 4%.
doi.org/10.1002/epi4...
#epilepsy #ILAE #epilepsiaopen #epilepsysurgery #LEAT #MCD #MRI #timing
Our findings suggest that ABI-009 is safe and tolerable in pediatric patients with surgically and medically refractory epilepsy at a dose of 20 mg/m2.
doi.org/10.1111/epi....
#epilepsy #epilepsia #ILAE #epilepsysurgery #malformationcorticaldevelopment #mTOR #tuberoussclerosis
Antiseizure medications, surgery, chemotherapy, and radiotherapy all contribute to controlling seizures and require a cooperative and multidisciplinary approach.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #antiseizuremedications #cerebraltumors #chemotherapy #epilepsysurgery #radiotherapy
SEEG-RFTC is a safe and effective option for reducing seizures in patients with complex networks or surgically inaccessible regions.
doi.org/10.1111/epi....
#epilepsy #ilae #epilepsia #drugresistantepilepsy #epilepsysurgery #radiofrequency thermocoagulation #SEEGguided #stereotactic
Corpus callosotomy was shown to be an effective long-term measure to decrease seizure burden in adults with drug-resistant epilepsy
doi.org/10.1002/epi4...
#epilepsy #ilae #epilepsiaopen #corpuscallosotomy #drugresistantepilepsy #epilepsysurgery #LennoxGastautsyndrome
This multicenter prospective study examined how seizure frequency and severity relate to long-term health-related quality of life after VNS.
doi.org/10.1111/epi....
#epilepsy #epilepsia #ILAE #drugresistantepilepsy #epilepsysurgery #pediatricepilepsy #qualityoflife #vagusnervestimulation
A logistic regression model including interictal MEG and SEEG features could well predict the postoperative prognosis of patients with an AUC of .81.
doi.org/10.1111/epi....
#epilepsy #epilepsia #ILAE #epilepsysurgery #highfrequencyoscillations #intracranialEEG #MEG #timelagnetwork
Incorporating both gray matter (GM) and superficial white matter (SWM) together improves surgical outcome differentiation.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #epilepsysurgery #graymatter #multimodal #superficialwhitematter
Multidimensional Outcome Reporting in Epilepsy (MORE) integrates seizure control, quality of life, treatment burden, and patient experience for comprehensive epilepsy outcome assessment.
doi.org/10.1111/epi....
#epilepsy #ILAE #epilepsia #outcomes #epilepsysurgery #qualityoflife
Key point: A measure of surgical targeting of lateralized FDG-PET hypometabolism was developed for use in epilepsy surgery planning.
doi.org/10.1111/epi....
#epilepsy #epilepsia #ilae #epilepsysurgery #FDGPET #seizureoutcomes
Key point: This study compares SLAH and HSATL in treating language-dominant TLE.
doi.org/10.1111/epi....
#epilepsy #epilepsia #ilae #temporallobectomy #languagedominanthemisphere #neuropsychologicaloutcomes #amygdalohippocampectomy #epilepsysurgery
Key point: Hippocampectomy does not significantly impact seizure freedom in TE-related epilepsy (RR = 0.66, p = 0.329).
doi.org/10.1002/epi4...
#epilepsy #epilepsiaopen #ilae #epilepsysurgery #hippocampectomy #seizurefreedom #temporalencephaloceles #temporallobeepilepsy
Key point: We scanned 31 patients with parallel transmit and conventional 7T magnetic resonance imaging (MRI), finding previously-unreported structural lesions in nine patients (29% of cases).
doi.org/10.1111/epi.... Open Access
#epilepsy #ilae #epilepsia #7TMRI #epilepsysurgery #focalepilepsy
Key point: Psychopathology was assessed in 103 pediatric surgical candidates with lesional epilepsy using diagnostic interviews and questionnaires.
doi.org/10.1111/epi....
#epilepsy #ilae #behavior #children #epilepsysurgery #outcome #psychopathology