A nonavalent BODIPY with a multivalent arrangement of α-mannosides enables lectins recognition in fluorescence-based assays We report here the use of Tris-BODIPY-OH as a scaffold for the multivalent display of sugar heads. A chloroacetyl thioether ligation reaction easily yields mannosylated BODIPYs, named Man9-BODIPY and (Man-TEG)9-BODIPY, which display nine mannose residues. Regardless of the linker length, both glycoBODIPYs provide a

📢New research from B Richichi et al presents Tris-BODIPY-OH as a universal scaffold for glycosylated #FluorescentProbes showing improved affinity for target lectins useful for studying lectin trafficking in vitro, in vivo and for #bioimaging applications
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Online now - the Review "Zn2+ transients and signaling in mammalian systems" from Ananya Rakshit and Amy Palmer.

#Zinc #ZincTransients #ZincSignaling #FluorescentProbes #LiveCellImaging

Read it here: authors.elsevier.com/a/1ltlt3S6Gf...

Fast, Bright and Reversible Rhodamine Tags for Live-Cell Imaging
Catapano, C., Dietz, M. S. et al.
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#LiveCellImaging #RhodamineTags #FluorescentProbes

#review #fluorescentprobes #ionchannels

Fluorescence-Based HTS Assays for Ion Channel Modulation in Drug Discovery Pipelines (Mertlíková-Kaiserová) -
ChemMedChem: doi.org/10.1002/cmdc...

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Making an impact with fluorescent probes - Nature Methods For Nature Methods’ 20th anniversary, our current and past editors reminisce about their favorite papers, initiatives and projects at the journal.

📜 Making an impact with fluorescent probes

🧑‍🔬 @ritastrack.bsky.social

📔 @natureportfolio.bsky.social Methods

🔗 www.nature.com/articles/s41...

#️⃣ #Microscopy #FluorescentProbes #Fluorophores #LightMicroscopy #FluorescentProteins

Recent advances in minimal fluorescent probes for optical imaging Fluorescent probes have revolutionized biological imaging by enabling the real-time visualization of cellular processes under physiological conditions…

📜 Recent advances in minimal fluorescent probes for optical imaging

🧑‍🔬 Fabio de Moliner, Ferran Nadal-Bufi, Marc Vendrell

📔 Current Opinion in Chemical Biology

🔗 www.sciencedirect.com/science/arti...

#️⃣ #Microscopy #Imaging #FluorescenceMicropscopy #FluorescentProbes