A new method called ME-MAGMA is designed to identify genes influenced by epigenetic regulators associated with epilepsy.
doi.org/10.1111/epi....

#epilepsy #ILAE #epilepsia #epigenetics #geneticgeneralizedepilepsy #GWAS #MAGMA #transcriptomics

A two-year terminal seizure freedom was more commonly achieved in patients with GTCA and GGE-NOS, compared to those with JME.
doi.org/10.1002/epi4...

#epilepsy #ILAE #epilepsiaopen #adultonset #antiseizuremedication #geneticgeneralizedepilepsy #seizureoutcome #terminalremission

Key point: We calculated polygenic risk scores for genetic generalized epilepsy and for focal epilepsy in individuals from 257 multiplex epilepsy families.
onlinelibrary.wiley.com/doi/full/10....

#epilepsy #ILAE #familialepilepsy #focalepilepsy #geneticgeneralizedepilepsy #polygenicriskscores