Tagging for the #GeroSky community - would welcome any discussion

🥳 Excited to share that our multi-omic study on the cellular impacts of Alu overexpression in healthy fibroblasts, co-led by former trainee Dr. Juan Bravo @the-te-guy.bsky.social and grad student Ms. Eyael Tewelde is out today in #Geroscience! 🧬🧪🖥️ #GeroSky
A 🧵 1/4
link.springer.com/article/10.1...

Using the “thrills and pleasures of horror” to explore aging and old age in Fear of Aging I still vividly recall the thrill of viewing Coralie Fargeat’s body horror triumph The Substance (2024) opening weekend with a packed audience at my local

Calling all horror fans! I'm pleased to share that my review of the essay collection "Fear of Aging: Old Age in Horror Fiction and Film" (edited by João Paulo Guimarães, 2025) has been published in The Gerontologist.

#FilmSky #BookSky #GeroSky

It's wonderful to see the number of outstanding applicants increase each year for our graduate student fellowships in collaboration with the UCSF Hillblom Center for the Biology of Aging. Congrats to this year's recipients! #GeroSky #SciSky

Targeting iron-associated protein Ftl1 in the brain of old mice improves age-related cognitive impairment - Nature Aging The authors identify ferritin light chain 1 (FTL1), an iron-associated protein, as a pro-aging neuronal factor that increases with age and promotes cognitive decline. Targeting FTL1 in the brain impro...

A recent manuscript published in @nataging.nature.com by Laura Remesal Gomez and the Villeda Lab identifies ferritin light chain 1 (FTL1) as a pro-aging neuronal factor that impairs #cognition, and as a potential target for cognitive #rejuvenation. Link to manuscript here: bit.ly/4lG46dp #GeroSky

Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis - Nature Communications Breast cancer cells interact with neighbouring adipocytes, but the mechanisms are not fully understood. Here, the authors show that triple-negative breast cancer (TNBC) cells transfer cAMP through gap...

How do tumor cells co-opt neighboring #adipocytes to promote #tumorigenesis? @andreigoga.bsky.social and colleagues identify a direct tumor cell-adipocyte interaction that activates lipolysis in triple negative breast cancer models. #SciSky #GeroSky bit.ly/4mRZYYN @natureportfolio.nature.com

For 60+ years, animals have been launched into space in an attempt to study microgravity’s effects on humans, but species differences hamper translation of findings.

In this @ufresearch.bsky.social study, a human muscle lab-on-a-chip was used in space to investigate muscle aging.

#gerosky 🧪

Studying ovarian aging and its health impacts: modern tools and approaches

Excited to see this new review piece that we wrote together with Jennifer Garrison and Alison Kochersberger on the modern tools and approaches to study #ovarian #aging out this week at @genesdev.bsky.social!
genesdev.cshlp.org/content/earl... #GeroSky #WomensHealth 🧪🧬
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Study: Iron Plays a Major Role in Down Syndrome-Associated Alzheimer’s Disease New USC research indicates how iron-related oxidative damage may hasten the development of Alzheimer’s disease in people with Down syndrome.

Study: Iron Plays a Major Role in #DownSyndrome-Associated #Alzheimers Disease gero.usc.edu/2025/06/19/s...

#dementia #health #wellness #gerontology #GeroSky

🚨 Preprint alert 🚨 , spearheaded by the talented Mr. #RyanLu, a graduate student: "Murine peritoneal macrophages undergo female-specific remodeling with aging", a functional genomics study of sex-dimorphism ♀️♂️ in #immune #aging 🖥️🧬🧪. #GeroSky #ImmunoSky 🧵, 1/13
www.biorxiv.org/content/10.1...

New Skeetorial time! 🦋
A new preprint led by Dr. #MinhooKim, where we present the characterization of #mouse models of #menopause using a combination of histology, endocrine measures, single-cell #transcriptomics, and #RNAscope validation! #GeroSky 🧪🖥️🧬 A 🧵 1/9
www.biorxiv.org/content/10.1...

📣 We are thrilled to announce @denadubal.bsky.social is joining our Executive Committee! Dr. Dubal's research investigates the molecular mechanisms of #aging, #resilience, and #neurodegenerative_disease. #SciSky #GeroSky

Cellular profiling identifies an early profibrotic alveolar type 2 cell signature in lung fibrosis Rationale Idiopathic pulmonary fibrosis (IPF) is a progressive, age-associated, lung disease characterized by short telomeres in alveolar type 2 (AT2) cells, epithelial remodeling, and fibrosis. Obje...

A collaboration between Mallar Bhattacharya and Paul Wolters shows that in a mouse model of IPF, early AT2 cell transdifferentiation and senescence is driven by enhanced p53 activity in response to #DNA damage. Out now on @biorxivpreprint.bsky.social: bit.ly/4dJG6DN #GeroSky #SciSky

RAND HRS Quarter 2 2025 Data Releases | Health and Retirement Study

🚨🚨🚨Some good news: the RAND Health and Retirement Study 2022 Longitudinal File and Fat Files are now available! Looking forward to distracting myself with some more recent data.

#Aging #GeroSky #EpiSky

hrs.isr.umich.edu/news/data-an...

Congratulations to our #SteeringCommittee member @katskaife.bsky.social who's had her abstract accepted for #BSG2025 🎉

"I've learned to live in a different way" - a process #evaluation of a #Norwegian long-term follow up after a #stroke intervention

@britishgerontology.bsky.social #GeroSky #Ageing

Aging activates escape of the silent X chromosome in the female mouse hippocampus Aging activates the silent X chromosome, increasing escape expression, and potentially cognitive resilience, in the female mouse.

Could a reawakening of the silenced X chromosome in females help slow aging-induced cognitive decline? Check out the work by @denadubal.bsky.social along with colleagues Kaitlin Casaletto, Bérénice Benayoun, and Vijay Ramani in Science Advances: bit.ly/3FlN3hj #GeroSky #SciSky

Our friends @bsgcarehomes.bsky.social are hosting an online symposium on 25th March on #Music in #CareHomes

Check out details and how to book in their post below ⤵️

#CreativeAgeing #GeroSky #Ageing #Dementia #MusicInHealth 🎵🎶

The GSA @geronsociety.bsky.social is seeking journal editors! Please apply if interested or share with your network! #geronsky #gerosky #agingsky

In this piece, we discuss best strategies to study #sexDifferences in #brain #aging, going over available models and methodologies, especially the ones we use as part of our collaboration supported by @simonsfoundation.org! #GeroSky 🧪🧬🖥️

Gerontological Society of America (GSA) is on Bluesky! bsky.app/profile/gero...
#geronsky #gerosky #gerontology #aginghealth #agingresearch #agingsky

Are you presenting at one of our #CreativeAgeing Symposia? Or perhaps elsewhere at #BSG2025? We'd love to hear from you - pop a comment below so we can share the movement 😉 #ArtsAndAgeing #GetInvolved #GeroSky 🦋

I just added some new folks. Let's keep the momentum going. Please let me know if you would like to be added.

#gerosky #gerontology #socialgerontology

go.bsky.app/KnsmUGh

A researcher's guide to studying sex differences in immune aging Sex differences in immune system aging significantly impact disease susceptibility and vaccine responses among older adults, but with notable disparit…

Congratulations 🎉 to the talented Clayton Baker and Minhoo Kim for the publication of their review of known #sexDifferences in #immune #aging, and the rodent model toolkit to study them, out today at Trends In Molecular Medicine! 🧬🧪
#GeroSky #ImmunoSky
www.sciencedirect.com/science/arti...

#AgingResearch
#GeroSky

Hey aging biology & geroscience researchers here’s your chance to voice your opinion about NIA’s future
#GeroSky
#AgingSky
#MedSky
🧪

Provide Input on NIA’s Strategic Directions for Research, 2026-2030 Help shape the future of NIA and aging research in the United States by providing your input on NIA’s Strategic Directions for Research for 2026-2030.

Aging biology and geroscience researchers can provide input on NIA's 2026-2030 strategic objectives. Scroll down to "Take a look at the latest framework and share your thoughts" to provide feedback:
www.nia.nih.gov/about/provid...

#agingresearch #geroscience #biologyofaging #GeroSky

Reversal of neuronal tau pathology via adiponectin receptor activation Communications Biology - Activation of adiponectin receptor signaling in tauopathy-prone primary neurons clears tangles through activation of lysosomes and rescues mitochondrial energetics, lipid...

New paper on metabolism & AD pathology- first author Eric McG crushes it rdcu.be/d5qox 💕 #GeroSky

Biological sex matters in brain aging

Biological sex is a key modifier of #aging phenotypes, including #Brain 🧠 aging.
See this piece out today in #Neuron, spearheaded by @denadubal.bsky.social, co-authored by #YousinSuh, @ctmurphy1.bsky.social and myself on the topic:
www.sciencedirect.com/science/arti...
#GeroSky #SexDifferences

#GeroSky this has gone offline again, it seems to no longer like the regex. Working on a fix…

😃 to release Clinical Gerontologist Issue 1, 2025 "Trauma and Resilience in Older Adults". www.tandfonline.com/toc/wcli20/c...
Featuring reviews, research, & clinical studies, Clinical Gerontologist focusing on behavioral health, we appreciate work with real-🌍 application. #gerisky #gerosky