Fibrillin-1 is a novel ligand of the epidermal growth factor receptor promoting mesangial cell activation and glomerulosclerosis

doi.org/10.1016/j.kint.2026.01.018

#MedSky #NephSky #glomerulosclerosis

#Renal focal global #glomerulosclerosis relates to #aging and #hypertension and begins with tuft contraction of #glomeruli. This report shows associated #biomarkers of #podocyte depletion, cell #senescence, and activation of #parietal #epithelia #cells.
doi.org/10.14814/phy...
#Kidney #Physiology