#Bacterial #enzyme & #nanoparticle discoveries hold promise for treating #gutpain

Scientists are targeting gut pain by discovering a new bacterial enzyme that activates pain receptors & using nanoparticles to deliver drugs that block them in cells scitechupdates.com/b...

Eeeeepy. I went to bed at about 4:30-5 AM after a very long Gossip Girl binge, insomnia, executive dysfunction, gut pain, and simply...vibing. Now to reckon with the consequences of my actions. [unhinged screaming begins in my brainhole] -Allēna #eepy #ActuallyAutistic #gutpain #IBS #NEISvoid

Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome Background Mast cell activation is an important driver of abdominal pain in irritable bowel syndrome (IBS). While evidence supports the role of IgE-mediated mast cell activation in visceral pain…

New study shows that MRGPRX2-mediated mast cell activation is heightened in patients with IBS, linking this pathway to increased abdominal pain and sensory hypersensitivity #IBS #AbdominalPain #GutPain

#Gut–#Brain🧠axis #Pain signalling mechanisms in #GI tract‼️ #GutPain
✅Most recent advances on molecular communication between non-neuronal cell types & #neurons in #VisceralPain
🎯Huge potential of #Neuromodulation in #DGBIs👏
👉https://nature.com/articles/s41575-024-01017-9
@natrevgastrohep.bsky.social