Vielversprechender Wirkstoff gegen Hepatitis E identifiziert | Deutsches Zentrum für Infektionsforschung Etwa 70.000 Menschen sterben jedes Jahr an Infektionen mit dem

🧵1️⃣ Der Wirkstoff Bemnifosbuvir kann auch das #HepatitisE- Virus an der Vermehrung hindern. Das zeigen Zellkultur-Versuche eines deutsch-chinesischen Forschungsteam. Das Nukleotid/Nukleosid-Analogon befindet sich derzeit in einer klinischen Studie zur Behandlung von #HepatitisC. /2

We are eager to learn about your new project ideas on #HepatitisE #virus! 🤩
And of course about the fun game you have there 🃏🐺

What a great meeting in Velbert last week 🔬

Under the title Advances in #HepatitisE Virus Infection Research, over 50 participants shared ideas and insights on clinical aspects, antiviral strategies, viral entry and replication 🧪

This is an amazing community, thanks to all of you 👇

#teamscience

Exciting news! 🎉
We’re proud to be part of the new HepE-Hub Bochum initiative!

Together with the uni clinics of @ruhr-uni-bochum.de and @mmv-rub.bsky.social, we’re committed to improve #HepatitisE virus #research and #healthcare

Check it out 🔎
#virology #infectionresearch #TRACiR

Welcome to the HepE-Hub Bochum!

We're thrilled to connect the #virology & #infection research @mmv-rub.bsky.social & @compvirol.bsky.social here at @ruhr-uni-bochum.de with its 5 uni clinics to boost #HepatitisE research & patient care.

Join us in our mission!
#teamscience

hepe-hub-bochum.de/en/

#HepatitisE virus (#HEV) is the most common cause of acute viral hepatitis in the world. Mainly decal-oral transmission acute, self-limited hepatitis in normal hosts. It can also cause chronic hepatitis in immunosuppressed patients. higher mortality rate in pregnant females.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681103/

#hepatitisE Virus #HEV genotype 3 t.co/upxAmHfMdl

Presenting Stimulator Grant 2025 Recipients:
💉 Michael Mastalerz and 🧫Viet Loan Dao Thi are working on a broad-spectrum antiviral therapy for #hepatitisE. This project aims to synthesize novel nucleobase antiviral compounds and inhibit HEV infection.
daothilab.bsky.social @uniheidelberg.bsky.social

Representing RUB @ruhr-uni-bochum.de at #HCVFlavi2025 conference. If you are on-site and interested in #hepatitisE check out Posters 10-15 to learn what's cooking I'm our labs @mmv-rub.bsky.social and www.tracir.de 🥣🚀

Screenshot of the first page of Table 1: Recommended Changes on the 2025 EML from the linked document, showing new medicines added and new indications.

All kinds of interesting developments on the new WHO Model List of #EssentialMedicines ( #EML).💊📜
#Ebola #mpox #CysticFibrosis #HepatitisE #diabetes
iris.who.int/bitstream/ha... #WHOMEML

Neutralizing human monoclonal antibodies against hepatitis E virus The Humoral Immunology Unit has identified neutralizing antibodies that are effective against the hepatitis E virus (HEV). They could be used for prevention or treatment against HEV infection, which a...

👩‍🔬 Scientists at Institut Pasteur identified powerful monoclonal antibodies that neutralize hepatitis E virus, which affects 20 million people yearly. #HepatitisE

💧 Prevenir es posible. Y urgente.
👉 Compartí esta información para generar conciencia y proteger a quienes más lo necesitan.
#HepatitisE #SaludMaterna #AguaSegura #Prevención #CuidadoEnElEmbarazo

#HepatitisE virus (#HEV) is the most common cause of acute viral hepatitis in the world. Mainly fecal-oral transmission acute, self-limited hepatitis in normal hosts. It can also cause chronic hepatitis in immunosuppressed patients. higher mortality rate in pregnant females.

Sources of Hepatitis E Virus Genotype 3 in the Netherlands Four subtypes have been detected, and pathogenicity, zoonotic potential, or stability may vary between subtypes. Keywords: Hepatitis E virus, transmission route, reservoir, environment, human, researc...

Ref pmc.ncbi.nlm.nih.gov/articles/PMC... #HEV #hepatitisE

#hepatitisE Virus #HEV genotype 3

Plasmacytoid dendritic cell sensing of hepatitis E virus is shaped by both viral and host factors Type I and III interferons critically protect the host against viral infection. Previous studies showed that IFN responses are suppressed in cells infected by hepatitis E virus (HEV). Here, we studied...

🚨New Pub🚨Plasmacytoid dendritic cell sensing of #hepatitisE #virus is shaped by both viral and host factors

Exciting work led by Dr Dreux @ciri-lyon.bsky.social in coll. with Dr Cocquerel’s team.

@pasteurlille.bsky.social @univlille.bsky.social @cnrs-hautsdefrance.bsky.social @inserm.fr

We are excited to share that our NanoX project has been featured in the Rhein-Neckar-Zeitung @rnzonline.bsky.social! Thank you to Amira Sanli for visiting our laboratories and showcasing our work in the newspaper!

#NanoX #HepatitisE #softxraytomography #cellbiology

Uno de nuestros compañeros de vacunación administra la vacuna contra la hepatitis E a una mujer en Hai Matar, condado de Fangak, Sudán del Sur, en la primera ronda de la campaña en diciembre de 2023. Foto de Gale Julius Dada

⚠️ “Mucha gente llama a la #hepatitisE el ébola de las mujeres embarazadas, porque tiene una tasa de mortalidad realmente alta: del 20 al 30% durante el embarazo”

John Johnson, asesor de vacunación de MSF

👉 https://a.msf.es/3-vacunas-prioritarias-mujer

Nakia John está siendo vacunada contra la hepatitis E. Nakia tiene 16 años y vive en el campo de desplazados internos de Bentiu, en Sudán del Sur.

🌍✨ BUENA NOTICIA ✨
Un estudio internacional demuestra que la vacuna contra la #hepatitisE es eficaz con solo dos dosis. 

Es un gran paso en la lucha contra esta enfermedad.

👉 https://a.msf.es/435KTMA

The Viral Most Wanted: The Parvoviruses and Hepeviruses In 1974, an Australian virologist called Yvonne Cossart was screening blood samples for Hepatitis B virus when she accidentally came across a new viral attacker.

Waterborne outbreaks of #HepatitisE are on the rise.

Affecting millions every year, this virus thrives in areas with poor sanitation.

Read more about this growing threat:

Niña junto a una zanja llena de aguas residuales en el campo de Bentiu. Las pésimas condiciones de saneamiento del campo de personas desplazadas internas de Bentiu provocaron en 2022 brotes de enfermedades transmitidas por el agua, entre ellas la hepatitis E. Foto de Peter Caton

La hepatitis E, que se transmite a través de agua contaminada, afecta principalmente a mujeres embarazadas y personas con enfermedades crónicas, pero ahora, con este avance, podemos proteger más vidas y reducir la mortalidad asociada.

🔬 #HepatitisE #SudánDelSur

Refugee camp study demonstrates effectiveness of two-dose Hepatitis E vaccine Hepatitis E is a viral infection that is particularly dangerous for pregnant women and people with chronic illnesses, with a mortality rate of up to 10-50 %.

Promising results from a two-dose #HepatitisE vaccine among refugees in #SouthSudan, with the vaccine reducing hepatitis E incidence even during an epidemic. zurl.co/fGcH8

The effectiveness of two doses of recombinant hepatitis E vaccine in response to an outbreak in Bentiu, South Sudan: a case–control and bias indicator study Despite the small sample size, our estimates provide evidence of effectiveness of a two-dose regimen against HEV genotype 1 during a protracted outbreak, supporting its use in similar contexts.

📢 Our study carried out after the first hepatitis E vaccination campaign in Bentiu, South Sudan shows that the two-dose regimen is effective, supporting its use in similar contexts.
#HepatitisE #vaccineswork 💉

@andrewazman.bsky.social
www.thelancet.com/journals/lan...

Un estudi de la UB apunta que els senglars podrien ser una font potencial de transmissió de l’hepatitis E a les persones en l’àrea metropolitana de Barcelona

#PapersBiologiaUB | 🐗 Els senglars podrien ser una font potencial de transmissió de l’ #hepatitisE a les persones en l’àrea metropolitana de #Barcelona.

Estudi coliderat pel professor Jordi Serra-Cobo i la Dra. Maria Isabel Costafreda.
web.ub.edu/web/actualit...

Immer mehr Hepatitis-E-Fälle: Die unterschätzte Gefahr in der Wurst In Deutschland ist es kaum bekannt: Brat- und Leberwurst können zur Hepatitis...

Ziemlich erschütternd:
• Ca. 400.000 Deutsche kommen jedes Jahr mit #HepatitisE in Berührung
• Seit 2004 hat sich die Zahl der Angesteckten ver-60-facht
• Eine Ursache: Schweinefleisch – jede fünfte Wurst enthält den Hepatitis-E-Erreger
https://t.co/qSegGqCNGh