🚨 Call for Late-Breaking Abstracts!
Share your newest hepatitis & antiviral research at #HepDART2025 🌺
📅 Deadline: Nov 17, 2025
📍 Hilton Hawaiian Village, Honolulu
Submit here 👉 informedhorizonseducation.com/abstracts-he...
#Hepatitis #LiverDisease #Virology #HepDART
🚨 Call for Late-Breaking Abstracts!
Share your newest hepatitis & antiviral research at #HepDART2025 🌺
📅 Deadline: Nov 17, 2025
📍 Hilton Hawaiian Village, Honolulu
Submit here 👉 informedhorizonseducation.com/abstracts-he...
#Hepatitis #LiverDisease #Virology #HepDART
@HepDART the curtain falls on the 2019 edition of #hepdart congratulations to @drugbuster21 and the organizing committee on another outstanding meeting and looking forward to the next!
@HepDART @norahterrault @KeckMedUSC summarizes her take on #HCV infected donors to neg recipients #hepdart
@HepDART @norahterrault @KeckMedUSC preemptive strategy of giving one week of #mavyret and #zetia seems to prevent development of #HCV after transplant in organs other than liver #hepdart
@HepDART @norahterrault @KeckMedUSC provides pros and cons of transplanting #HCV infected livers in HCV uninfected persons #hepdart
@HepDART @norahterrault @KeckMedUSC published experience with transplanting #HCV viremic livers still very small <30 and there may be signal for increased rejection #hepdart
@HepDART dr. Manns: if #HBV DNA PCR undetectable no need for HBIG peri or post transplant. Give HBIG if #HDV coinfection #hepdart
@AligosThera @HepDART dr. Lawrence Blatt’s blueprint towards functional cure: STOPs, ASOS, CAMs and maybe all of the above #hepdart
@ArbutusBio @HepDART dr. Sofia’s take on what it takes to achieve #HBV functional cure #hepdart $ABUS
@HepDART dr. Bruce Given: #HBV RNAi JNJ-3989 can achieve powerful HBsAg reduction across all genotypes & seems well tolerated. Probably need long term combo rx to achieve functional cure @ArrowheadPharma #HEPDART
@HepDART dr. Becky Taub: histological improvement in absolute fat reduction % by MRI-PDFF on #resmetirom in ph2 compared to other drugs in development $MDGL #hepdart
@HepDART dr. Thomas Baumert: human liver cell atlas and single cell RNA sequence analysis could be a way to identify disease MOA #HEPDART
@HepDART dr. Martins @AllerganBio reviews regulatory agency requirements for #NASH drug approval. @US_FDA requires improved fibrosis OR NASH resolution whereas @EMA_News requires BOTH #hepdart
@HepDART dr. Martins @Allergan doing #NASH clinical trials is hard. Here is a laundry list of why... #hepdart
@HepDART dr. Martins @Allergan summarizes ph3 trials planned in progress #obeticholicacid #cenicriviroc #aramchol #resmetirom #elafibranor #belapectin #galectin #hepdart
@HepDART Dr. Eduardo Martins @Allergan #NAFLD is underreported and increasing in prevalence #hepdart
@HepDART Prof. Manns: we Do need a cure for #HDV infection among other reasons because only a sterilizing (not functional) cure of #HBV is required for this to happen #hepdart
@HepDART dr. Lok @MichiganLiver should we realistically expect drugs that result in #HBV functional cure to be as safe as nucs? May be setting bar too high! #hepdart
@HepDART dr. Lok @MichiganLiver lays out her “realistic” criteria for functional cure endpoints #hepdart
@HepDART dr. Lok @MichiganLiver since #HBsAg loss even in absence of seroconversion seems to confer durable #HBV virological suppression, regulators incl. @US_FDA should not require seroconversion as an endpoint for functional cure drug approval #hepdart
@HepDART dr. Anna Lok @umichmedicine @MichiganLiver a “realistic” #HBV functional cure could be HBsAg loss +/- sAb seroconversion with regression of fibrosis #hepdart
@HepDART dr. Vaillant: ALT flares during #HBsAg reduction to 1 IU/ml w/ Nucleic Acid polymers (NAP) +PegIFN therapy predict functional cure of #HBV #hepdart #replicor
@HepDART dr. Mayers: ATI-2173 is a liver targeted 5’-monophosphate of #clevudine which may get around off target myopathy toxicity of clevudine seen in ph2/3 studies #hepdart
@GlobalVirusNews @HepDART @HepDART prof. Brechot: the next epidemics will likely be caused by new viruses evolved from existing viruses #hepdart
