#Resmetirom (REZDIFFRA) gegen metabolische Dysfunktion-assoziierte #Steatohepatitis (MASH)
Erstmals ist ein Mittel zur Behandlung der metabolischen Fettleberhepatitis im Handel, doch ein klinischer Nutzen ist bislang nicht nachgewiesen.
www.arznei-telegramm.com/de/6465/resm...
NASH/MASH Treatment Market Set for Dramatic Growth, Expected to Reach Over $31 Billion by 2033 #USA #Austin #NASH_Treatment #MASH_Treatment #Resmetirom
🚨 𝐍𝐨𝐰 𝐨𝐧𝐥𝐢𝐧𝐞 🚨
Our latest article evaluates the budgetary impact of pathways using cT1 versus SoC (liver biopsy or VCTE) to assign suspected #MASH patients to #resmetirom. See the graphical abstract below for an overview of the study.
Click the link for the full article 👉 bit.ly/4g3dLJQ
📗 ICYMI: Editor-in-Chief of Clinical Research, Elliot B. Tapper, MD, FAASLD, shares the latest highlights from Hepatology Communications including articles on #SLD, #MASLD and #ALD, diet, #resmetirom eligibility, and more! View the latest issue online: bit.ly/4oeZ8qE
Video: bit.ly/4odW8KZ
AASLD’s Practice Statement on #MASLD in children is available in #HEPATOLOGY Early View! This important resource builds on our comprehensive MASLD guidance, including #resmetirom updates & other publications shaping the future of clinical care. journals.lww.com/hep/fulltext...
Early returns on my #resmetirom #rezdiffra #MASH patients at 1 year. So far 7/8 patients reasessed with LSM have a 30% or greater reduction. Hopefully we start getting some real world data to complement the open label trial.
#liversky
🚨 Now online🚨
Discover the budget impact of #resmetirom as a treatment for adults with non-cirrhotic non-alcoholic steatohepatitis with moderate-to-advanced liver fibrosis and estimated total costs for a hypothetical US private payer. Read the article here👉 bit.ly/4iWpfiq
#liverdisease #HEOR
A new treatment to improve outcomes in #MASLD: #implementation, accessibility, and health system implications of #Resmetirom | npj Gut and #Liver
🚨 New Expert Panel Recomm. Alert 🚨
🔗📗 tinyurl.com/3he6rybk
💡Expert panel shares practical tips on initiating & monitoring #Resmetirom for #MASH with moderate to advanced fibrosis.
@cugastrohep.bsky.social @amergastroassn.bsky.social @aga-cgh.bsky.social
Hello~ Kickstarting the blue sky with an introduction: I am Victoria, currently doing a #PhD at #RijksuniversiteitGroningen #UMCG on #MASLD using #OrganOnChip specifically #LiverOnChip to model #steatotic liver disease and explore #steatohepatisis and interventions e.g. #resmetirom, happy to connect
Thank you @jechristensen @WayneEskridge1 and @CNN for raising awareness about steatotic liver disease and treatment options w #rezdiffra #resmetirom #livertwitter @FattyLiverA @GlobalLiver @KnowledgeNash https://dir.lat/iWDRK7
Summary of DDI management with #rezdiffra #resmetirom
✅ Rosuvastatin and simvastatin: no more than 20 mg/d
✅ Pravastatin and atorvastatin: no more than 40 mg/d
✅ reduce by 20 mg with clopidrogel
🛑 don’t use with Gemfibrozil and cyclosporine
#livertwitter
#livertwitter among your #MASH patients who would you prioritize #resmetirom for?
#resmetirom is #rezdiffra the first ever @US_FDA approval in the steatotic liver disease space #livertwitter
Tomorrow is the @US_FDA PDUFA date for #resmetirom. Not since #sofosbuvir has a potential drug approval been more anticipated. This has been an arduous process for #MASH therapeutics.
Hoping we take a first step tomorrow. #livertwitter
@EASLedu @EASLnews improvement in MRE and #VCTE at both 100 and 80 mg doses of #resmetirom limitations include low fibrosis burden in participants. AE included diarrhea and nausea mostly in the first 12 weeks. #ILC2022
@EASLedu @EASLnews both 80 and 100 mg doses of #resmetirom in MAESTRO-NAFLD1 achieved secondary endpoints #ILC2022
@EASLedu @EASLnews Dr. Steve Harrison @Pinnacle_TX presents data for ph3 #resmetirom MAESTRO-NAFLD1 study. Design shown below #ILC2022
@HepDART dr. Becky Taub: histological improvement in absolute fat reduction % by MRI-PDFF on #resmetirom in ph2 compared to other drugs in development $MDGL #hepdart
@HepDART dr. Martins @Allergan summarizes ph3 trials planned in progress #obeticholicacid #cenicriviroc #aramchol #resmetirom #elafibranor #belapectin #galectin #hepdart