Intercellular communication from myotubes to fibroblasts is differentially impacted by mineralocorticoid receptor signaling and muscular dystrophy - Cell Communication and Signaling Cell Communication and Signaling - Replacement of striated muscle with fibrosis leads to the symptoms and fatality in Duchenne muscular dystrophy (DMD). Transient local production of the...

Happy to share our recent publication on intercellular communication from the Rafael-Fortney lab. Check this one out!
#fibroblasts #myotubes #DMD #skeletalmuscle #fibrosis

link.springer.com/article/10.1...

This study investigates possible off-target effects of the often-used antibiotic #streptomycin on myoblast cell function. Reduced global #protein #synthesis rate in differentiating #myotubes is reported, while #myoblast proliferation is unaffected.
doi.org/10.14814/phy...
#MyoBlue #CellPhysiology

Development of an in vitro platform for the analysis of contractile and calcium dynamics in single human myotubes In vitro myotube cultures are widely used as models for studying muscle pathophysiology, but their limited maturation and heterogeneity pose significant challenges for functional analyses. While they ...

📢 Check out our recent work published in Lab on a Chip, describing a novel platform for the measurement of #contractility and #calcium dinamics in single human #myotubes with low variability and high reproducibility
👉 doi.org/10.1039/D3LC...
#myoblue 🧪