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Basic research on Listeria bacteria leads to unique cancer therapy After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the…

Basic research on #Listeria #bacteria leads to unique #cancer therapy ...

| #immunesystem | #listeriosis | #pathogen | #phagosome | Via @sciencex.bsky.social

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Membrane receptors cluster phosphatidylserine to activate LC3-associated phagocytosis - Nature Cell Biology Here the authors show that LC3-associated phagocytosis is initiated by various receptors, which enrich phosphatidylserine in the membrane domains proximal to the phagosome, recruiting Rubicon to the membrane for phagosome maturation.

💫NEW: Here the authors show that LC3-associated #phagocytosis is initiated by various receptors, which enrich #phosphatidylserine in the membrane domains proximal to the phagosome, recruiting Rubicon to the membrane for #phagosome maturation.
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Cheng, Qiu et al @jhu.edu provide new insights into the molecular mechanism of #phagosome maturation and the dynamics of host defense response following phagosome-mediated bacterial degradation in peritoneal #macrophages. rupress.org/jem/article/...

#InnateImmunity #inflammation #InfectiousDisease

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