Thank you @ajhgnews.bsky.social for sharing our latest PaperCast!

Integrating polygenic risk scores with social determinants of health is key for equitable genomic medicine across populations.

#Genomics #PrecisionMedicine #PolygenicRisk #PublicHealth

Dr Cristina Hickman responds to Peter Thompson, Chief Executive of the @HFEA recent article published in BioNews: www.progress.org.uk/pgt-p-in-the...

#PolygenicRisk #Risk #PolygenicRiskScores #HFEA #Embryology #Reproduction #GeneticTesting #Fertility #Regulation #FertilityClinics #Law

A new genome-based CVD test integrates monogenic, polygenic, and #pharmacogenomic data, offering scalable and comprehensive risk insights with minimal interpretation burden. bit.ly/3NACxaj #GIMO #CardiovascularDisease #GenomeSequencing #PolygenicRisk #MonogenicDisease

TV Review by Dr Matteo Cortese: Hitler's DNA – Blueprint of a dictator
This BBC programme investigates what the DNA reveals about Hitler's heritage.
The full review is free-to-access on our website:
www.progress.org.uk/tv-review-hi...

#Genetics #DNA #genomics #genetictesting #polygenicrisk

If you are attending the #PETconf25 then here is a must-read BioNews comment piece about PGT-P written by Professor Angus Clarke - panellist in Session 4
Read in BioNews: www.progress.org.uk/the-clinical...

#PGTP #PolygenicRiskScores #PolygenicRisk #Embryos #Fertility #Genetics #DNA

Researchers Analyze DNA Believed to Belong to Hitler, Reveal Possible Genetic Condition Analysis of Hitler’s DNA Suggests Rare Hormonal Condition, Genetic Study Sparks Debate A team of researchers led by Turi King

Researchers studying DNA believed to belong to Hitler reveal a rare hormonal disorder, confirm ancestry, and assess psychiatric risk in a Channel 4 documentary.

#HitlerDNA #HistoricalGenetics #KallmannSyndrome #PolygenicRisk #GeneticResearch

Associations Between Structural Phenotype and Polygenic Risk Scores in Intermediate Age-Related Macular Degeneration - A MACUSTAR Report - PubMed Our findings reveal subgroups in iAMD based on genotype-phenotype associations which can help identifying patients at high risk for iAMD and establish new endpoints for clinical trials in iAMD.

MACUSTAR study links structural biomarkers in intermediate AMD (RPD, cRORA) to pathway-specific polygenic risk scores—advancing precision risk stratification & trial design. #AMD #Ophthalmology #Genetics #PolygenicRisk #PrecisionMedicine #VisionResearch buff.ly/SyjrWEg

Can your athletic past raise your risk for atrial fibrillation? Elite retired rowers face a nearly threefold increased risk of atrial fibrillation compared to the general population, driven by a combination of long-term cardiac remodelling and underlying polygenic...

Can your athletic past raise your risk for atrial fibrillation? www.news-medical.net/news/2025062... #AtrialFibrillation #Athletes #Genetics #HeartHealth #Rowing #Endurance #Cardiology #Stroke #PolygenicRisk #SportsScience @escardio.bsky.social

Congratulations @jenberkman.bsky.social on your amazing 3MT yesterday! 👏

Jen’s research focuses on empowering clinicians to explain polygenic risk scores to patients and customise screening based on personal risk, so it’s just about them.

Stay tuned! 📚

#3MT #PolygenicRisk #PersonalisedMedicine

Why Alzheimer’s DNA tests don’t treat all populations equally A major global study tested whether European-derived polygenic risk scores (PGS) for Alzheimer’s disease can predict risk across diverse populations. While PGS performed well in many groups, it was le...

Why Alzheimer’s DNA tests don’t treat all populations equally www.news-medical.net/news/2025061... #Alzheimers #Genomics #GWAS #PolygenicRisk #Diversity #PrecisionMedicine #Neurodegeneration #APOE

Mediterranean eating habits help European children fight genetic obesity risk A large European cohort study found that adherence to the Mediterranean diet mitigates the impact of genetic risk for obesity in children, especially in early childhood. High consumption of vegetables...

Mediterranean eating habits help European children fight genetic obesity risk www.news-medical.net/news/2025052... #MediterraneanDiet #Obesity #Genetics #ChildHealth #Nutrition #Prevention #Adiposity #PolygenicRisk #HealthyEating #Pediatrics

Researchers uncover 195 genetic risk factors driving women’s reproductive diseases Scientists identified 195 genetic risk loci across 42 female reproductive health conditions, revealing shared genetic pathways and developing a polygenic risk score for intrahepatic cholestasis of pre...

Researchers uncover 195 genetic risk factors driving women’s reproductive diseases 🔬🧬💡 www.news-medical.net/news/2025031... #Genetics #WomensHealth #ReproductiveHealth #Genomics #PrecisionMedicine #PolygenicRisk #GWAS #Hormones #Medicine

Just attended a fantastic talk by @tatyanes.bsky.social 🎤 on bridging the gap to implementing polygenic risk scores 🧬 and genomic testing 🏥 in clinical practice—so many great insights from her research and clinical experience🔬✨ #Genomics #PolygenicRisk #genechat

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links Researchers uncovered 1,307 genetic loci linked to metabolic syndrome, revealing brain tissue enrichment and key genetic factors in its development. The study also shows polygenic risk scores predict ...

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links 🔬🧬🌍 www.news-medical.net/news/2024100... #MetabolicSyndrome #Genetics #PolygenicRisk #BrainHealth #GWAS #Cardiovascular #Health #PersonalizedMedicine #GeneticLoci

@uk_biobank #canalization #polygenicrisk #PGSxE #complextraits #commondiseases