"We analysed Hitler’s DNA – and what we discovered made us gasp" Turi King and Alex J Kay have married genetics with history to study a sample of DNA from Adolf Hitler – and, as they reveal, their research has thrown up some extraordinary insights into the Nazi dic...

“… #Hitler … well-known deletion in a #gene that is associated with #KallmannSyndrome & the elaborately named #Congenital #hypogonadotropic #hypogonadism”
… genital organs were almost freakishly underdeveloped”
…
#polygenicscore placed him in the #top1% for schizophrenia, #autism & #bipolardisorder”

The results emphasize that while the autism polygenic score (PGS) provides important insights for research, it lacks clinical utility at this time. #autism #genetics #polygenicscore

Don't miss William Li's presentation 1050W this afternoon at the
@geneticssociety.bsky.social, American Society of Human Genetics.

Learn more about our presentations: bsky.app/profile/yosu....

#polygenicscore #biobanks #alzheimers #subtypes #heterogeneity #ASHG #ASHG25

Metabolomic and genomic prediction of common diseases in 700,217 participants in three national biobanks - Nature Communications Identifying individuals at high risk for chronic diseases can improve prevention. Here, the authors show that blood metabolomics scores effectively stratify disease risk and compare favorably to genet...

Long awaited peer review finally completed!! Our paper comparing quantitative metabolomics disease risk prediction with PGS is accepted in Nature Comms!! 🥳🥳
@nightingalehealth.com #riskprediction #metabolomics #nmr #genomics #polygenicscore

www.nature.com/articles/s41...