Tele-rehabilitation for individuals with Long COVID. A Randomized Clinical Trial BackgroundMost trials in long COVID rehabilitation included only previously hospitalized patients and omitted outcome measures such as mobility, an important outcome for assessing life impact. Primary objective: to investigate whether an 8-week tele-rehabilitation program for individuals with long COVID improves functional mobility compared to usual care.Methods and FindingsRandomized controlled trial involving individuals with long COVID and persistent symptoms of reduced mobility, muscle weakness, dyspnea, or fatigue. Participants were randomized to either an individualized 8-week tele-rehabilitation program plus usual care or usual care. In both groups, usual care was supplemented with generic guidance on physical activity and symptom management. Primary outcome: Activity Measure for Post-Acute Care (AM-PAC) mobility. Secondary outcomes: dyspnea, fatigue, quality of life, physical function, mental health, acceptability, and adverse events.132 participants were randomized (65 intervention; 67 control; 48±11.8 years; 75% female), with 78% not previously hospitalized. Adherence was high (96%), though 39% of intervention participants were unable to progress their exercises. No significant between-group differences were found in AM-PAC mobility (mean difference (MD): 0.61; 95% CI −0.91 to 2.13). The intervention group showed greater improvements in EQ-5D-5L pain (MD: −0.36; 95% CI −0.70 to −0.03), health status (MD: 7.74; 95% CI 1.05 to 14.43), fatigue (MD: −0.90; 95% CI −1.78 to −0.02), and dyspnea (MD: 1.24; 95% CI 0.10 to 2.37). No serious adverse events occurred.ConclusionsIn the context of limited evidence around exercise in non-hospitalized individuals with long COVID, our study offers important insights into feasibility, safety and clinical relevance.

Our paper on tele-rehab in #longcovid is now published in ERJ Open Research : publications.ersnet.org/content/erjo...
#rehab #postcovid #postcovidcondition #rimuhc @mcgillrehab.bsky.social

“Perceived poor work ability is common among people with PCC,” … “it is crucial to implement individually tailored interventions to support individuals towards increased activity & participation in all aspects of life, including work."

#PostCOVIDCondition #PCC #WorkAbilityScore #research #Sweden

💙 Thank you to our wonderful volunteers, trustees and supporters.

SHH-UK would not exist without your time, care and dedication to supporting healthcare workers living with Long Covid.

#LongCovid #LongCovidAwareness #LongCovidSupport #LongCovidRecovery #PostCovidCondition

PhD defence alert! Demi Pagen presents "The spectrum of COVID-19 epidemiology: from public health alarm state to long-term struggle" on April 22 at 13PM @maastrichtu.bsky.social.

#CoronavirusDisease #COVID19 #LongCovid #PostCOVIDCondition

💻 📘 Check the link in bio!

#longcovid #postcovidcondition #covid19 #infectiousdiseases #research #naturecommunications #nature #covidpersistente #condicionpostcovid19

#Longcovid #Postcovidcondition #Research #NatureCommunications #highlights

@nature.com @naturecomms.bsky.social @lmateu.bsky.social @rutgerwalls.bsky.social @fundaciolluita.bsky.social

This.

We keep being told that Covid is a novel virus, and post covid condition is new and not understood.

So yes, I want to be a case study, I will want to be dissected and my tissues used for study.

#Longcovid #postcovidcondition

Hi Adriana! It’s me Kimberly (we chatted today in Messenger). Agreed 💯 that infighting is waste of our precious energy. We have the opportunity to learn much from each and other chronic illness groups as well. Keep up the great advocacy! #longcovid #postcovidcondition #chronicillness

Exploring Long COVID Prevalence and Activity Limitations Among Children in the U.S. — SCIENMAG In 2023, post–COVID condition (PCC), often referred to as “Long COVID,” has emerged as a significant health concern among children in the United States. This issue continues to be prevalent at levels ...

‘As the understanding of PCC continues to evolve, so too does the need for robust data collection practices. Ongoing research efforts must incentivize long-term data gathering on #children diagnosed with #PostCovidCondition’

apple.news/A0uyCzph4RkG...

#LongCovidKids #Paediatric #LongCovid

#longcovid #postcovidcondition

Preventing infection in children should be high priority.

Please share this study with those who have the power to protect all children.

@gwynnemp.bsky.social
@wesstreeting.bsky.social

www.sciencedirect.com/science/arti...

#PostCovidCondition #LongCovid #LongCovidKids #Education

Long COVID Breakthrough: Spike Proteins Persist in Brain for Years Researchers have discovered that the SARS-CoV-2 spike protein persists in the brain and skull bone marrow for years after infection, potentially leading to chronic inflammation and neurodegenerative d...

scitechdaily.com/long-covid-b...

#LongCovid
#CovidIsNotOver
#PostCovidCondition
#Covid19

SARS-CoV-2 antivirals and post-COVID-19 condition Post-COVID-19 condition (also known as long COVID)—the term that encapsulates the long-term health effects caused by SARS-CoV-2 infection—is a complex multisystemic chronic disease with profound conse...

Here's the link to the piece in The Lancet that is referenced in the thread above:

SARS-CoV-2 antivirals and post-COVID-19 condition - The Lancet Infectious Diseases
www.thelancet.com/journals/lan...

#PostCovidCondition #PCC #LongCovid #Antivirals

Screenshot of abstract

New review from Germany:

Towards an understanding of physical activity-induced post-exertional malaise: Insights into microvascular alterations & immunometabolic interactions in #postCOVIDcondition & #MEcfs

link.springer.com/article/10.1...

#PEM #LongCovid #ChronicFatigueSyndrome #PwME

3/

“(Contd) as measured by the DSST, and sets shifting, as measured by the TMT-B, in persons with PCC."

#PostCovidCondition

3/

“(Contd) We also demonstrated that men and women suffering from PCC must be considered separately. Therefore, the variability in PCC must be taken in regard together with sex-specific differences."

#PostCovidCondition #CovidLong

2/

“(Contd) Further research is needed to understand the specific mechanisms underlying a limited exercise capacity and post-exertional malaise in patients with #postCOVIDcondition and ME/CFS”
#MEcfs #LongCovid #LC #PwME