Our second abstract is by Asifa Khan, who is studying proteoglycan undersulfation in ECM homeostasis and musculoskeletal ageing at the Università di Pavia. Please contact Asifa if you would like to know more.
#MSCA_DN #ECM #proteoglycans #ageing #raredisease
📣Poster abstract submission and rego for the 13th International Proteoglycan Meeting & the Annual Scientific Meeting of MBSANZ have been extended!
📅Poster Abstract deadline - 29/8/25
📅New Early Bird deadline - 29/8/25
Register now!
👉 mbsanz2025.smalltalkevents.com.au
#Proteoglycans #ECM
❗ Check out this new Review!
Matrix: a complex amalgam of structures and functions in tumor microenvironment
🔓 buff.ly/HvYWq9r
#CD44 #Integrins #Proteoglycans #TumourMicroenvironment
Abstract submission and registration for the 13th International Proteoglycan Meeting & the Annual Scientific Meeting of MBSANZ are now open!
📅Abstract deadline - 30/5/25
📅Early Bird deadline - 31/7/25
Register now to secure your spot!
👉 mbsanz2025.smalltalkevents.com.au
#Proteoglycans #ECM
Looking forward to co-chairing the session on #proteoglycans at the @matrixbiologie.bsky.social DGMB annual meeting in Freiburg with Christine Huang. @uni-muenster.de
The Dance of Life: Unveiling the Heroes and Troublemakers Within Our Body
#Biology #Proteoglycans #Inflammation #Health #Microbiology #CentralNervousSystem #Chemokines #Leukocytes #AmyloidProteins #Endotoxins #BodySymphony #WellnessJourney
youtube.com/shorts/YI5K0...
#ECMatrix researchers, please share:
Just under 2 weeks until the abstract deadline (21st Feb) for the 3-day Matrix Nexus meeting in Freiburg. Topics include #cancer #collagens #proteoglycans #proteases #tissueengineering & a session dedicated to #ECRs!
www.matrixbiologie.de/annual-meeti...
HSPGs in SARS-CoV-2 infection and EV uptake
Viral infection
Heparan sulfate (HS) as a portal of entry for EVs and SARS-CoV-2 viral particles. A: EVs carry membrane-associated proteins whose relative abundance highly depends on the status of the secreting cell. leadina to heterogeneous populations of EVs in tissues and in circulation. The expression levels of proteoglycans and other cell membrane receptors at the target tissue, together with specific EV-ligand proteins likely dictate EV tropism. B: SARS-CoV-2 particles are relatively less heterogeneous than EVs in their molecular composition; however SARS-CoV-2 variants differ in the efficiency of infection. ACE and HSPG tissue expression influence SARS-CoV-2 infection. C: mechanistically, EV transfer to recipient cells may occur via 1) direct fusion of lipid membranes or via an endoctic route following attachment to membrane receptors. Heparan sulfate proteoglycans (HSPGs) can 2) bind to polybasic domains of membrane EV proteins or 3) proteins associated to the EV surface by electrostatic inter
Deciphering the Role of Proteoglycans and Glycosaminoglycans in Health and Disease
journals.physiology.org/doi/pdf/10.1...
#Proteoglycans: a common portal for #SARSCoV2 and extracellular vesicle uptake
journals.physiology.org/doi/full/10....
Abstract
MedSky🧪#Pathology Did you know that #proteoglycans are involved in various human diseases including global #infections, regenerative medicine & #angiogenesis? @iozzo_v
a comprehensive review on the global impact of proteoglycan on human diseases
www.cell.com/iscience/ful...
