Integrins—mediators of cell-matrix and cell-cell adhesion - Lasker Foundation Explore All 2022 Winners & Awards > Richard O. Hynes Massachusetts Institute of Technology Erkki Ruoslahti Sanford Burnham Prebys Timothy A. Springer Boston Children’s Hospital/Harvard Medical School For discoveries concerning the integrins—key mediators of cell-matrix

Happy birthday to #LaskerLaureate Tim Springer! 🧪
He was recognized for discoveries concerning the #integrins –key mediators of cell-matrix and cell-cell adhesion.
Tim Springer Lab
Harvard Medical School
Boston Children’s Hospital
https://ow.ly/erMQ50YkipP
https://ow.ly/kB2o50YkipN

Happy birthday to #LaskerLaureate Erkki Ruoslahti! Ruoslahti was recognized for discoveries concerning the #integrins —key mediators of cell-matrix and cell-cell adhesion in physiology and disease. 🧪
Sanford Burnham Prebys
http://ow.ly/bQYY50MTLif

In @jcb.org, Lerche, Mathieu, @johannaivaska.bsky.social @ivaskalab.bsky.social et al. reveal that newly synthesized #integrins can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance cell protrusion and #adhesion. rupress.org/jcb/article/...

Lerche, Mathieu, @johannaivaska.bsky.social @ivaskalab.bsky.social et al. reveal that newly synthesized #integrins can bypass the Golgi to be actively delivered to specific plasma membrane regions, where they enhance cell protrusion and #adhesion. rupress.org/jcb/article/...

[OPEN]: Special Postdoctoral Fellow Position (2025) | Springer Lab

📢 The Springer Lab is hiring!

Advance groundbreaking research at the intersection of integrin signaling, organoid development, and receptor mechanobiology.

#PostdocJobs #ECRchat #PhDChat #Integrins #Mechanobiology #CellBiology #Organoids #RegenerativeMedicine #SpringerLab

🔬 Welcome to the Springer Lab

Follow along to see how structure, mechanics, and biology come together to shape life at the molecular level.

#Integrins #TGFbeta #Mechanobiology #StructuralBiology #Biophysics #Organoids #RegenerativeMedicine #SpringerLab

Antibodies Against Membrane Protein Targets | Discovery on Target | Sept 22 - 25, 2025 Antibodies Against Membrane Protein Targets provides a forum in which discovery biologists and protein engineers can come together to discuss biologic drugs for the GPCR and more!

Lots of excitement at the Discovery on Target conference next week!
🎯André Teixeira will share IPI's high-throughput discovery platform and lead a discussion on GPCR #abdiscovery (Sept. 23)
🎯IPI co-founder Tim Springer will give a keynote on #integrins and their role in organoid formation (Sept. 24)

❗ Check out this new Review!

Matrix: a complex amalgam of structures and functions in tumor microenvironment

🔓 buff.ly/HvYWq9r

#CD44 #Integrins #Proteoglycans #TumourMicroenvironment

📚 New Review now online

Interplay of integrins and selectins in metastasis

🔓 buff.ly/TAwbF4l

#Integrins #CellAdhesion #Selectins #CancerMetastasis

What a great week at the #Fibronectin, #Integrins & related molecules #GRC. Inspiring and interesting talks, and the opportunity to speak to so many amazing people in the field. Really hope to be able to join you all again in 2027

Extracellular vesicles adhere to cells primarily by interactions of #integrins and GM1 with laminin, say Tatsuki Isogai, Kenichi Suzuki (Gifu University) and colleagues: rupress.org/jcb/article/...

#Biophysics #Membrane #lipid

What a view for science! ☀️⛰️
#GRC on #Fibronectin, #Integrins and Related Molecules is going strong in Renaissance Tuscany Il Ciocco with a beautiful backdrop. I am happy to share my work on focal adhesion mechanics in my first-time Gordon conference with the brightest minds in the field. 🔬

Happy birthday to Erkki Ruoslahti, 2022 #LaskerLaureate! Ruoslahti was recognized for his discoveries concerning the #integrins —key mediators of cell-matrix and cell-cell adhesion in physiology and disease. @sbpdiscovery.bsky.social https://buff.ly/4hDrpTS

The novel ECM protein SNED1 mediates cell adhesion via the RGD-binding integrins α5β1 and αvβ3 Summary: The recently discovered extracellular matrix protein SNED1 promotes the adhesion of breast cancer cells and neural crest cells via interaction with α5β1 and αvβ3 integrins, the first SNED1 re...

Our paper entitled "The novel #ECM protein SNED1 mediates cell adhesion via the RGD-binding #integrins α5β1 and αvβ3" is now published in #OpenAccess in @jcellsci.bsky.social @biologists.bsky.social. Big congrats Dharma pdtr124.bsky.social and Nandini! doi.org/10.1242/jcs....

Go to the #GRS stay for the #GRC. some of my favourite discussions have happened at this meeting, I dunno if I can go but I highly encourage anyone interested in #fibronectin #integrins and all #RelatedMolecules, go see cool science, chat to great scientists and all in a not to shabby region of 🇮🇹

🧪Very interesting findings with implications in #cancermetastasis 👇

#mechanotransduction
#cancerresearch
#ECMatrix
#integrins

Extracellular Vesicle Mobility in Collagen I Hydrogels Is Influenced by Matrix-Binding Integrins Extracellular vesicles (EVs) are a diverse population of membrane structures produced and released by cells into the extracellular space for the intercellular trafficking of cargo molecules. They are ...

New paper out on extracellular #vesicle (EV) mobility in #collagen I #hydrogels!
How #integrins on EV surfaces influence EV movement through tissue-like environments.

pubs.acs.org/doi/10.1021/...