I am very happy that @mprothiwa.bsky.social joined us today for a department visit and a lecture. She gave a very interesting lecture on "Chemical strategies to understand bacterial immune evasion".
link.springer.com/protocol/10....
#ChemBio #ChemSky #Bacteria #Proteases #Probes

Neutrophils and the NLRP3 inflammasome: a tale of proteases, kinases, and inflammation Cell type–specific mechanisms modulate Nod-like receptor family pyrin domain containing 3 inflammasome activation in macrophages and neutrophils, shaping i

"#Neutrophils and the #NLRP3 #Inflammasome: a tale of #Proteases, #Kinases, and #Inflammation" - read the new Review by Vinicius Leal @uspoficial.bsky.social & Alexander Weber @unituebingen.bsky.social

The #DPPIV family #proteases were thought to function just as dipeptidyl #peptidases, cleaving only after proline or alanine. Here, Trivedi and Gudipati report that C. elegans DPF-3 and human DPP4 possess previously unrecognized tripeptidyl peptidase activity.

➡️ doi.org/10.1002/1873-3468.70219

#research #immunology #proteases

Allergenic mites excrete cathepsins B and C as active cysteine proteases distinct from group 1 allergens
(Pytelková, Orsághová, Beňová, Horn, Schabussova, Mareš) – Int. J. Biol. Macromol.: doi.org/10.1016/j.ij...

@iocbprague.bsky.social #1LFUK @meduniwien.ac.at

COVID-19: A Disease Driven by Protease/Antiprotease Imbalance? A Specific Review Five Years into the Pandemic COVID-19, caused by SARS-CoV-2, has profoundly impacted global health since late 2019. Beyond respiratory complications, the disease involves systemic manifestations driven by immune dysregulation, in...

#Medsky🧪 #IDsky #Immunosky # public health A comprehensive overview of how a dysregulated balance between #proteases (enzymes that break down proteins) & their inhibitors (antiproteases) can drive the systemic complications observed in #COVID .
pmc.ncbi.nlm.nih.gov/articles/PMC...

Looking for a PhD ? Don’t miss ⬇️
12 PhDs available in the REMOD-HEALING European doctoral network, funded by Horizon Europe's MCSA-DN program, in Europe and Costa Rica !
www.euraxess.fr/jobs/375945
@themeshwork.bsky.social @matrixbiologie.bsky.social
#ECM #collagen #WoundHealing
#proteases

Mitochondrial proteases and their roles in mitophagy in plants, animals, and yeast Abstract. Mitochondria play a central role in cellular respiration and other essential metabolic and signaling pathways. To function properly, mitochondria

🆕REVIEW:

Ludwig & Heidorn-Czarna discuss recent advances in the study of mitochondrial #proteases and #mitophagy across #plants, #animals, and #yeast, providing fresh insight into the mitochondrial protein quality control system in plants 🌱

🔗 doi.org/10.1093/pcp/...

#Organelles
#PlantScience

This review summarizes advancements in solubility and controllable aggregation tags for recombinant protein purification, highlighting design strategies, on-demand cleavage, and emerging production challenges.
#HM #protein #purification #tags #proteases
www.sciltp.com/journals/hm/...

📣We offer a #PhDposition @dfg.de-funded #RTG2670 BEAM: "Beyond Amphiphilicity - Self-Organization of Soft Matter via Multiple Noncovalent Interactions" with @marischuster.bsky.social.

🔗More: www.ipb-halle.de/en/career/jo...

📅Apply now!

#MolecularModelling #Proteases #SciJobs #PhDjobs

The Enzyme Effect: How Proteolytic Powerhouses Fight Pain, Boost Recovery, & Supercharge Digestion In today's episode we're diving deep into proteolytic enzymes, also known as "protein-eaters," crucial biological catalysts that break down proteins. You'll discover how these 580+ microscopic machines can supercharge your digestion by improving nutrient absorption and promoting gut health.  Learn how they fight inflammation and pain as effectively as some prescription drugs for arthritis, speed recovery from injuries, and boost your immune system. We’ll also cover potent natural food sources like papaya and pineapple, plus when to consider high-quality supplements. Source: https://foodnourish.net/proteolytic-enzymes/

📣 New Podcast! "The Enzyme Effect: How Proteolytic Powerhouses Fight Pain, Boost Recovery, & Supercharge Digestion" on @Spreaker #absorption #actinidin #athletes #bromelain #digestion #enzymes #foods #gut #healing #health #immune #inflammation #joints #nutrients #pain #papain #proteases

We just published one of our #research protocols as a STAR protocol 🌟.

Check out our protocol if you are interested in #macrophage #proteases! 🔬✨

#AcademicTwitter #OpenScience #researchmethods #immunosky

New cover!❤️‍🔥
#Proteases are key regulators of #inflammation, yet their role in immune responses to #implanted_materials remains lagerly unexplored. On the cover we illustrated how different materials elicit distinct protease responses, offering a signature of material-induced immune activation💫

#ECMatrix researchers, please share:

Just under 2 weeks until the abstract deadline (21st Feb) for the 3-day Matrix Nexus meeting in Freiburg. Topics include #cancer #collagens #proteoglycans #proteases #tissueengineering & a session dedicated to #ECRs!

www.matrixbiologie.de/annual-meeti...

Amazing to see this beautiful work in its final form!
Many congratulations @pierrebuscaill.bsky.social et al!
#PlantChemeticsLab #Proteases

A snapshot of the Physcomitrella N-terminome reveals N-terminal methylation of organellar proteins bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution

New preprint, now with full text:
A snapshot of the #Physcomitrella N-terminome reveals N-terminal methylation of organellar proteins
#ndegron #proteases #moss
www.biorxiv.org/content/10.1...