Endothelial cell–released CD93 contributes to podocyte injury in idiopathic nephrotic syndrome Soluble CD93 contributes to podocyte injury, and CD93 blockade emerges as a candidate therapeutic target in INS.

Great paper from @carafuentes-neph.bsky.social !!
Tackling #nephroticsyndrome from many angles, better treatments are on the horizon!
Congrats Gabriel & team!!!!
#FSGS #pediatricnephrology #NephSky #SkyNeph #humangenetics
@science.org
www.science.org/doi/10.1126/...

Thank you @asnpublications.bsky.social !!!
This is a true honor, and a sprinkle of good luck!

#FSGS #rFSGS #raredisease #APOL1 #CAKUT #NephSky #SkyNeph
@asnkidney.bsky.social
@isgd.bsky.social

Highly recommended contribution from Detlef Bockenhauer et al: a modern view of the genetic landscape of kidney diseases!
#genetics #CAKUT #FSGS #APOL1 #NephSky #SkyNeph #Medsky #raredisease #RKD
@melaniechan.bsky.social @oalavijeh.bsky.social @horiastanescu.bsky.social @dannygale.bsky.social

I spent >20y to try to make a name of myself with hard research, and the Gloria (formerly Nicki), the dog we just rescued, is already famous and published on Vogue!
@teenvogue.com @time.com @nytimes.com
#americanbulldog #bostonterrier #NephSky #SkyNeph #MedSky

web.archive.org/web/20250819...

Thank you @opeyemiolabisi.bsky.social and the whole @dukekidney.bsky.social , @gbadegesinlab.bsky.social , Laura Barisoni et al!
It was a great couple of days of scientific excellence mixed with pleasant company and nice weather.
#APOL1 #FSGS #rFSGS #genetics #pediatrics #NephSky #SkyNeph #Medsky

Exome analysis links kidney malformations to developmental disorders and reveals causal genes - Nature Communications The authors analyze rare coding variants in 1990 individuals with congenital kidney anomalies, finding diagnostic variants in 14.1% of cases. They identify two new causal genes, ARID3A and NR6A1, alon...

Fresh online on @natcomms.nature.com ! Great collaboration with the lead team at GharaviLab / CPMG.
Large exome-wide analysis that points to many findings, including two novel genes: ARID3A and NR6A1.
#CAKUT #humangenetics #development #pediatrics #NephSky #SkyNeph

www.nature.com/articles/s41...

At the #PodocyteConference you don’t meet only great scientists, but also interesting personalities, like Brian Kennedy, 4-times Grammy award winner and patient advocate. With Matt Sampson & Elena Martinelli
#NephSky #SkyNeph
@kidneyomicsamps.bsky.social
#FSGS #rFSGS #APOL1
@isgd.bsky.social

It truly was an amazing conference!
#podocyteconference #Medsky #Nephsky #Skyneph #FSGS #rFSGS #APOL1
@isgd.bsky.social @tobias-b-huber.bsky.social

More from the #podocyte2025 with @kidneyomicsamps.bsky.social and Laura Mariani
#podocyte #hamburg #FSGS #rFSGS #genetics #Nephsky #Medsky #Skyneph
@isgd.bsky.social

Before and after.. with mythological beings Stu Shankland and Andrey Shaw at #podocyte2025 in #Hamburg
@isgd.bsky.social
#Nephsky #Skyneph #Medsky

It’s not just working and giving talks at the 7th International Renal Meeting with @mayoclinic.org in #Sardinia
#FSGS #rFSGS #CAKUT #RareDisease #APOL1 #NephSky #SkyNeph #MedSky

Great to see @alessiafornoni.bsky.social and Pars in #Cagliari for the 7th renal meeting with @mayoclinic.org in #Sardinia
#FSGS #rFSGS #CAKUT #RareDisease #APOL1 #NephSky #SkyNeph #MedSky

From MC1R to MC5R, a new horizon for the podoprotective effect of melanocortin

doi.org/10.1016/j.kint.2025.01.026

Original article: doi.org/10.1016/j.kint.2025.01.009

#KICommentary #NephSky #MedSky #SkyNeph #glomerulardisease

Thrombotic microangiopathy following scorpion envenomation

doi.org/10.1016/j.kint.2024.10.033

#KINephrologyImage #NephSky #MedSky #SkyNeph

Transgenic human nephrin in Drosophila nephrocytes facilitates variant analysis.

doi.org/10.1016/j.kint.2025.03.030

#NephSky #MedSky #SkyNeph #nephroticsyndrome

Renal involvement in aceruloplasminemia

doi.org/10.1016/j.kint.2024.10.032

#KINephrologyImage #NephSky #MedSky #SkyNeph #KidneyPath #RenalPath

Executive summary of the #KDIGO 2025 Clinical Practice Guideline for the Management of #NephroticSyndrome in Children

doi.org/10.1016/j.kint.2024.11.006

#OpenAccess #NephSky #MedSky #SkyNeph #glomerulardisease

Treatment of patients with #IgAnephropathy: a call for a new paradigm

doi.org/10.1016/j.kint.2025.01.014

#OpenAccess #NephSky #MedSky #SkyNeph #IgAN #KIReview #kidneydisease

Gene signature-guided drug screening identified narciclasine as a potential therapeutic for interstitial fibrosis of the kidney

doi.org/10.1016/j.kint.2025.03.021

#NephSky #MedSky #SkyNeph #CKD #chronickidneydisease

B cell-derived exosomal miR-483-5p and its potential role in promoting kidney function loss in IgA nephropathy

doi.org/10.1016/j.kint.2025.03.019

#OpenAccess #MedSky #NephSky #SkyNeph #IgAN #IgAnephropathy

Single-cell analysis of proximal tubular cells with different DNA content reveals functional heterogeneity in the #acutekidneyinjury to #chronickidneydisease transition

doi.org/10.1016/j.kint.2025.03.025

#NephSky #MedSky #SkyNeph #AKI #CKD

#CRISPR-Cas9 mediated proteinase 3 autoantigen deletion as a treatment strategy for anti-neutrophil cytoplasmic autoantibody-associated vasculitis

doi.org/10.1016/j.kint.2025.03.020

#OpenAccess #MedSky #NephSky #SkyNeph #AAV

Recurrent #kidneystones in a young man with Caroli disease

doi.org/10.1016/j.kint.2024.09.024

#KINephrologyImage #urology #mineralmetabolismn #NephSky #MedSky #SkyNeph

It's been a good #KidneyMonth! Let's make it a good #KidneyYear2025 for #rFSGS.

#MedSky #NephSky #Skyneph #FSGS #RareDisease #KidneyTransplant #genetics #humangenetics #nephroticsyndrome #pediatrics

This is a great opportunity for advanced trainees/junior faculties to get hands-on experience as Editors in the top nephrology portfolio! Join us and have fun with us trying to constructively push authors to publish their best science!
#Nephsky #Skyneph
@asnkidney.bsky.social @aspnr.bsky.social

As #KidneyMonth2025 ends, we want to hear from you all on what continues to inspire you and provide hope for a future where a cure for #rFSGS exists! Let us know your thoughts and experiences in the comments below. ⬇️

#rFSGSConference #KidneyTransplant #nephsky #medsky #skyneph

Help us understand why!

If you or someone you know has #rFSGS and you are interested in learning how you can help and provide a biosample, email us at mb5150@cumc.columbia.edu.

#KidneyMonth #KidneyMonth2025 #rFSGSConference #KidneyTransplant #nephsky #medsky #skyneph

Age- and sex-specific reference values of estimated glomerular filtration rates for European adults

doi.org/10.1016/j.kint.2025.02.025

#OpenAccess #NephSky #MedSky #SkyNeph #EGFR #ckd #chronickidneydisease

Concurrent AL amyloidosis and fibrillary glomerulonephritis

doi.org/10.1016/j.kint.2024.08.036

#KINephrologyImage #NephSky #MedSky #SkyNeph #RenalPath #KidneyPath @mayoclinicpath.bsky.social

Insights from ADPedKD, #ERKReg and RaDaR registries provide a multi-national perspective on the presentation of childhood autosomal dominant polycystic kidney disease in high- and middle-income countries

doi.org/10.1016/j.kint.2025.02.026

#NephSky #MedSky #ADPKD #PedNeph #SkyNeph