Tofacitinib and Iguratimod Combination Shows Promise in PPF Tofacitinib and iguratimod show dual efficacy in controlling synovitis and pulmonary fibrosis, according to a new study.

#Tofacitinib combined with #Iguratimod shows dual efficacy in controlling #Synovitis and #LungFibrosis. Study in Frontiers in Immunology.

Read more: https://bit.ly/4tqBIkB

#RareDisease #Immunology #ProgressivePulmonaryFibrosis

Tofacitinib may increase skeletal muscle mass in rheumatoid arthritis A proof-of-concept study suggests that treatment with the JAK inhibitor tofacitinib could increase skeletal muscle mass in patients with rheumatoid arthritis.

#MedNews - A proof-of-concept study suggests that treatment with the JAK inhibitor #tofacitinib could increase skeletal muscle mass in patients with rheumatoid #arthritis.

Full story 👉 buff.ly/aXYCzYY

#RheumSky

Effective treatment of pretibial myxoedema with tofacitinib: a case report and analysis of immunopathogenesis A man with Graves disease and orbitopathy presented with bilateral pretibial myxedema. Oral tofacitinib was initiated after transient response to intralesional glucocorticoids‒edema and orbitopathy…

#MedCase - A man with #GravesDisease and orbitopathy presented with bilateral pretibial myxedema.

Oral #tofacitinib was initiated after transient response to intralesional glucocorticoids‒edema and orbitopathy improved within 1 month.

👉 buff.ly/3dWCxLG

#EndoSky

Research Article

Effective Treatment of Janus Kinase 1/3 Inhibitor in Blau Syndrome From a Multicenter Retrospective Study in Central China

📖 www.jrheum.org/cgi/content/...

#Blausyndrome #Januskinaseinhibitors #tofacitinib

A Jak/Stat inhibitor, #Tofacitinib, can suppress IFNg production from ILCs and T cells, reducing tissue damage during ameliorates #Campylobacter www.mucosalimmunology.org/article/S193...

Diffuse filiform polyposis in a patient with ulcerative colitis A man with ulcerative colitis refractory to anti-TNF therapy was assessed for mucosal healing after sustaining clinical and biochemical remission on tofacitinib. Colonoscopy revealed finger-like…

#MedCase - A man with #UlcerativeColitis refractory to anti-TNF therapy was assessed for mucosal healing after sustaining clinical and biochemical remission on #tofacitinib.

Colonoscopy revealed finger-like mucosal projections carpeting the entire colonic mucosa.

👉 buff.ly/P55iDS3

#GastroSky

Tofacitinib: Todo lo que Necesitas Saber sobre su Uso, Beneficios y Efectos Secundarios ¿Qué es tofacitinib y para qué sirve? Tofacitinib es un medicamento que pertenece a la clase de los inhibidores de la quinasa Janus (JAK). Este fármaco se utiliza principalmente en el tratamiento de diversas... The post Tofacitinib: Todo lo que Necesitas Saber sobre su Uso, Beneficios y Efectos Secundarios first appeared on SoloSalud.net.

Tofacitinib: Todo lo que Necesitas Saber sobre su Uso, Beneficios y Efectos Secundarios #Tofacitinib #Salud #Medicamentos

Tofacitinib proves effective for persistent rashes in juvenile dermatomyositis: 87.5% of pediatric patients saw significant skin improvement and reduced steroid use in new clinical study.

#Meded #SoMe4PedSurg #Tofacitinib #JuvenileDermatomyositis #Pediatrics

link.springer.com/article/10.1...

Tofacitinib for the treatment of chronic pouchitis: A pilot study Tofacitinib achieved clinical remission in 31% of chronic pouchitis patients after 8 weeks, of treatment, with significant reductions in total and clinical PDAI scores but no significant changes in e...

💡Can chronic pouchitis be treated with a JAK inhibitor?

In our pilot study, 31% reached clinical remission after 8 weeks of tofacitinib. PDAI scores dropped significantly, though mucosal healing was not (yet) achieved.

📄 doi.org/10.1002/ueg2...
#IBD #pouchitis #tofacitinib

Comparative safety of JAK inhibitors versus TNF or IL-17 inhibitors for cardiovascular disease and cancer in psoriatic arthritis and axial spondyloarthritis To compare the risk of cardiovascular disease (CVD) and common solid cancers between JAK inhibitors (JAKi) versus TNF or IL-17 inhibitors, among peopl…

🚨 #Tofacitinib ⬆️ #cardiovascular & #cancer risk in RA. But how relevant is this risk to people with #AxialSpondyloarthritis or #PsoriaticArthritis?

This study did not find ⬆️risk of JAK compared to TNF or IL17 inhibitors in SpA. Funded by PAPAA.
www.sciencedirect.com/science/arti...

Planning to Switch up Your JAK Inhbitor for Alopecia Areata? Patients Requiring a Switch from Tofacitinib to Baricitinib Seem to do Well — Donovan Hair Clinic Low Chance of Hair Loss Among Patients Requiring a Switch from Tofacitinib to Baricitinib   JAK inhibitors are used to treat more advanced forms of alopecia areata. There are many reasons why...

Need to switch your patient with alopecia areata from Tofacitinib to Baricitinib for some reason? Most patients with alopecia areata seem to do just fine with the switch! donovanmedical.com/hair-blog/to... #alopeciaareata #tofacitinib #baricitinib

In a recent episode of the Evidence Based Hair Podcast, I discussed the safety of JAK inhibitors in pregnancy. m.youtube.com/watch?v=-Zap... #alopeciaareata #jakinhibitors #ritlecitinib #baricitinib #tofacitinib

Janus Kinase Inhibitors | COVID-19 Treatment Guidelines Review information on the use of Janus kinase inhibitors for the treatment of COVID-19.

Several #JAKinhibitors are available for clinical use, but only #baricitinib & #tofacitinib have been studied for the treatment of #COVID19.

www.covid19treatmentguidelines.nih.gov/therapies/im...

Tofacent 5mg, also known by its generic name Tofacitinib, is a medication that belongs to the class of Janus kinase (JAK) inhibitors.
#Tofacent5mg #Tofacitinib #Medicine #Health #OnlineMedicine #MedicineStore #AntiCancer #LiverCancer
iebpharma.com/product/tofa...