Good to read😝

Proud to share our latest preprint! 🥳
Using a multidisciplinary approach, we uncover a dual function of the snR37 H/ACA snoRNP - combining pseudouridylation with ribosome chaperone activity within a single RNP.🔬🧬
Challenging the traditional view of snoRNP function. 👇
#cryoEM #ribosome #RNA #snoRNA

Love this color🩵🩵

NAA40 and NAC cooperate in co-translational histone acetylation in humans pubmed.ncbi.nlm.nih.gov/41820326/ #cryoEM

Congrats 🎉🎊🍾
Many thanks to all the contributors 🥳🥳

Congrats🥳Our cryo-EM structure reveals how NAC recruits NAA40 and may coordinate with METAP1 to couple methionine removal with histone acetylation.

How are histones modified while they are still being synthesized?
We show that NAA40 works together with the NAC complex at the ribosome to acetylate histones H2A and H4 co-translationally.

Our cryo-EM structure reveals how NAC recruits NAA40 and may coordinate with METAP1 to couple methionine removal with histone acetylation.

Many thanks to all the contributors！🥰

NAA40 and NAC cooperate in co-translational histone acetylation in humans - Nature Communications N-terminal histone acetylation by human NAA40 alters epigenetic signaling and affects gene regulation. Here, the authors combine biochemistry and cryo-EM to unravel the foundation for the co-translati...

Attention handsome people and brilliant minds ！👀🤩

😜🥳Our new paper out in Nature Communications!
@natcomms.nature.com
@beckmannlab.bsky.social
@timodenk.bsky.social
@kirmizislab.bsky.social
@arielchk.bsky.social

#cryoEM#ribosome#translation#histones

🤩Link: www.nature.com/articles/s41...

Happy Lantern Festival 🏮
Wishing everyone perfect ice, good particles, and zero beam damage.
#cryoEM#cryoET#structurebiology
#Chineseculture

super cool！

🎉Thrilled to share that our lab has been awarded an ERC Synergy Grant @erc.europa.eu! Excited for amazing collaborations with the Pertschy (Uni Graz), Henras (CBI Toulouse), and Woodson (Johns Hopkins) labs.
#ERCSyG #GeneCenter #LMU #UniGraz #CNRS #JohnsHopkins

🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social&@chipericson.bsky.social trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬
www.biorxiv.org/content/10.1...

Congrats🥳

Lori Passmore

We’re looking for a #postdoc to join Lori Passmore’s group, within a programme aimed at understanding addition of mRNA poly(A) tails

More info: www.nature.com/naturecareer...
Closes 06 OCT
#ScienceJobs #PostdocJobs

Great start to the EMBL translation control meeting with a keynote from @lapassmore.bsky.social. Excited for all the science to come. #EMBLProtein