Our new study is out in Nature Communications.
Using TNBC organoid mouse models, we show that necroptosis in both tumour and stromal compartments cooperatively drives effective responses to immunogenic cell death–based immunotherapy.

🔗 www.nature.com/articles/s41...

‘Treasure trove’ of antiviral proteins could inspire powerful molecular tools Two research teams mined genomic data from bacteria to create databases containing thousands of antiviral defence proteins that could inspire powerful biotechnologies.

Bacteria have been fighting off viruses using a huge arsenal of molecular weaponry that scientists did not know about — until now. Researchers have identified proteins that could lead to virus-fighting drugs and technologies.

go.nature.com/4dqQnXI

Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF Upstream open reading frames exert translational control of TNFR1, which limits tissue responsiveness to TNF.

I am delighted that our study “Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF”, led by Biao Ma, is published in Science Immunology.

#TNFR1, #inflammation, #CellDeath, #Immunopathology, #Tissue_tolerance
@sic-ucph.bsky.social @ludwigcancer.bsky.social

doi.org/10.1126/scii...

Upstream open reading frames exert translational control of TNFR1, which limits tissue responsiveness to TNF @sciimmunology.bsky.social @gyrd-lab.bsky.social @ox.ac.uk
www.science.org/doi/10.1126/...

ICYMI: This collection highlights the latest discoveries in the field of #InnateImmunity in viral #infection, barrier defense, liver health, #inflammation, and #cancer. Explore latest discoveries in JEM 👉 rupress.org/jem/collecti...

Registration now open! 2026 #EMBO #Ubiquitin Workshop set in stunning Monopoli, Puglia 🇮🇹
Cutting edge science, great speakers, short talk opportunities, travel awards
Limited spaces. Dont miss out - register early!
Registration & more info: meetings.embo.org/event/26-ubi...

Perspective @cp-cellchembiol.bsky.social
Transcending cell death – The diverse roles of necroptosis signal adaptors in pathogen infection
www.cell.com/cell-chemica...

Join us for the EMBO workshop on Pathogen Immunity and Signalling #embopathogensignalling

Abstract submission extended until 15 February.

bsky.app/profile/embo...

This is an excellent meeting for anyone interested in immunology, virology, host-pathogen interactions, immune signalling. Abstract submission deadline is 1 Feb.

Pathogen Immunity and Signalling Viruses, bacteria, and other pathogens pose a serious threat to human health, requiring a coordinated response from the innate and adaptive immune systems. Our immune system relies on pathogen recept…

Explore #immunology, #virology, #microbiology and more at EMBO Workshop "Pathogen Immunity and Signalling" in Leiden, NL, 8–11 June 2026.

Abstract submission/Registration deadline: 1 February/15 March

https://meetings.embo.org/event/26-pathogen-immunity
#EMBOpathogenSignalling #EMBOevents 🧪

📣 SIC Summer School 2026 — applications open!
📍Hornbæk, DK | 18–20 May 2026
🎯Theme: Skin Immunity & Homeostasis
💵Free (stay + meals). For PhD students & postdocs.
✍️Deadline: 15 Jan 2026 (23:59 CET).
🔗Full details: sic.ku.dk/summerschool/
🔗Register here: eventsignup.ku.dk/sicss2026