Exosomes: New Biomarker and Therapeutic Candidates in Autism Spectrum Disorder Research | Acta Neuropsychiatrica | Cambridge Core Exosomes: New Biomarker and Therapeutic Candidates in Autism Spectrum Disorder Research

⚠️ Caveats:
• As in psychiatry, no single, universal biomarker exists. The future likely lies in multi-marker panels.
• Findings are primarily preclinical; human translation is the next critical step.

Read more: doi.org/10.1017/neu....
#Neuroscience #Biomarkers #ASDResearch #Exosomes

Research study recruitment flyer seeking women diagnosed with ASD enrolled in college/university. Qualifications include formal ASD diagnosis and 60+ college credits. Features illustration of woman with headphones studying at laptop. Study involves confidential 45-60 min interview, reflective questionnaire, all online. Participants entered in raffle for $100 Amazon gift card. Contact: ifan414@regiscollege.edu. QR code and website link included.

Contact: ifan414@regiscollege.edu
Website: autisticwomenincollege.as.me

#AutismResearch #WomenWithAutism #CollegeStudents #ASDResearch #AutisticWomen #ResearchStudy #HigherEducation #NeurodiversityInCollege

Blog - First Step Behavioral Services Helpful articles and expert insights on autism, ADHD, evaluations, psychology, and mental health—supporting families across North Carolina.

New research - details on my website blog - click the link below:
Gut Problems in Autism Linked to Sleep, Behavior, and Sensory Challenges

firststepbehavioralservices.com/blog/
#mentalhealth #ASDresearch

Blog - First Step Behavioral Services Helpful articles and expert insights on autism, ADHD, evaluations, psychology, and mental health—supporting families across North Carolina.

This suggests autism and epilepsy may share the same brain pathway and gives scientists a new target for future treatments.
Read more about it on my blog firststepbehavioralservices.com/blog/
#autism #treatment #science #researh #ASDResearch

🤔Could #ASD scans be misleading?📉 #GMV↓ in #Cerebellum ↑ #Cortex 🧠GMC↓ temporal/frontal ↑ #ACC
🔍Patterns shift with #Age🌟 @elsevierconnect.bsky.social @sciencedirect.bsky.social #Autism #Neuroimaging #ASDResearch #BrainScience
Read+RT!
doi.org/10.1016/j.ne...

Redirecting

🤔Could #ASD scans be misleading?📉 #GMV↓ in #Cerebellum ↑ #Cortex 🧠GMC↓ temporal/frontal ↑ #ACC
🔍Patterns shift with #Age 🌟 @elsevierconnect.bsky.social @sciencedirect.bsky.social #Autism #Neuroimaging #ASDResearch #BrainScience
Read+RT!
doi.org/10.1016/j.ne...

Redirecting

🤔Could #ASD scans be misleading?📉 #GMV↓ in #Cerebellum ↑ #Cortex 🧠GMC↓ temporal/frontal ↑ #ACC
🔍Patterns shift with #Age🌟@Elsevier @sciencedirect.bsky.social #Autism #Neuroimaging #ASDResearch #BrainScience
Read+RT!
doi.org/10.1016/j.ne...

Characterization of astrocyte density in the Pitt-Hopkins Syndrome mouse model of ASD
Bohlen, J. F., Maher, B. et al.
Paper
Details
#AstrocyteDensity #PittHopkinsSyndrome #ASDResearch

At 12 mos, infants with elevated genetic likelihood for ASD show reduced social-communication & attention (esp. responding to/initiating social attention) vs. EL-ADHD & low-risk peers. No sig.
parent-reported differences for EL-ADHD vs. controls; early ADHD signs may be less detectable.
#ASDresearch

https://www.cell.com/ajhg/fulltext/S0002-9297(24)00412-9 No description available

Study reveals that genetic variants in DDX53 from the Xp22.11 locus contribute to ASD, which has a 4:1 male-to-female ratio. #ASDResearch PMID:39706195, Am J Hum Genet 2025, @AJHGNews www.cell.com/ajhg/fulltext/S0002-9297... #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Mis-splicing of a neuronal microexon promotes CPEB4 aggregation in ASD | Nature The inclusion of microexons by alternative splicing occurs frequently in neuronal proteins. The roles of these sequences are largely unknown, and changes in their degree of inclusion are associated with neurodevelopmental disorders1. We have previously shown that decreased inclusion of a 24-nucleotide neuron-specific microexon in CPEB4, a RNA-binding protein that regulates translation through cytoplasmic changes in poly(A) tail length, is linked to idiopathic autism spectrum disorder (ASD)2. Why this microexon is required and how small changes in its degree of inclusion have a dominant-negative effect on the expression of ASD-linked genes is unclear. Here we show that neuronal CPEB4 forms condensates that dissolve after depolarization, a transition associated with a switch from translational repression to activation. Heterotypic interactions between the microexon and a cluster of histidine residues prevent the irreversible aggregation of CPEB4 by competing with homotypic interacti

Study: Mis-splicing of a 24-nt neuronal microexon in RNA-binding protein CPEB4 linked to ASD. Microexon inclusion changes in neuro disorders? #ASDResearch PMID:39633052, Nature 2025, @Nature https://doi.org/10.1038/s41586-024-08289-w #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

Study reveals that genetic variants in DDX53 from the Xp22.11 locus contribute to ASD, which has a 4:1 male-to-female ratio. #ASDResearch PMID:39706195, Am J Hum Genet 2025, @AJHGNews www.cell.com/ajhg/fulltext/S0002-9297...

Study reveals that genetic variants in DDX53 from the Xp22.11 locus contribute to ASD, which has a 4:1 male-to-female ratio. #ASDResearch PMID:39706195, Am J Hum Genet 2025, @AJHGNews www.cell.com/ajhg/fulltext/S0002-9297...

APHRC is training field interviewers for an Autism Spectrum Disorders(ASD) study in Nairobi & Kiambu Counties. The study explores care, education, & support for children with ASD to inform inclusive policies.

#InclusiveEducation #ASDResearch #APHRCResearch #WeAreAfrica

⚠️ Critical Conclusion:
After 6+ years of review, reliable evidence remains inconclusive about ABA's true efficacy

Source: Hayes Medical Literature Review, cited in internal DoD document

#ASDResearch #EvidenceBasedPractice #CriticalThinking

Co-designing with adult people with ASD: A review of applied tools and techniques | Adjunct Proceedings of the 2022 Nordic Human-Computer Interaction Conference You will be notified whenever a record that you have chosen has been cited.

a while ago, we did a review of co-design with #autistic adults in HCI, identifying six key techniques (observations, interviews, make tools, workshops, prototyping, surveys). Found opportunities to refine methodological approaches in this space. #HCI #ASDresearch

dl.acm.org/doi/abs/10.1...