%Sourdough loaf (stiff starter)
Organic %Rye flour + organic T80 flour
#Autolysis 2 hrs
Overnight proofing 9 hrs
Baked on a pizza stone

Top: Organisation of the nap island in Neisseria gonorrhoeae FA1090. Grey arrows, flanking genes (NEIS0808, pseudouridine synthase; NEIS0794, histidyl-tRNA synthase); blue arrows, genes coding for GG-containing peptides; orange arrows, genes predicted to be involved in peptide processing and secretion; green arrow, gene of unknown function; pink boxes, Correia elements. Bottom: Transmission electron microscopy images from bacteria in HEPES (T = 75 min). Some wild-type bacteria appear normal (indicated with arrow numbered 1), with many others having a dense (arrow 2) or very dense (arrow 3) cytoplasm, periplasmic expansions (arrow 4), or appearing as ghost cells (arrow 5). Extracellular vesicles (arrow 6) and released cellular content (arrow 7) are also visible. Periplasmic expansions are not observable in the ΔltgA or ΔnapRABC strains. Cytoplasm condensation appears more homogenous in the ΔltgA mutant.

Programmed cell death distinguishes N. gonorrhoeae & N. meningitidis from other #Neisseria species. @katyponcin.bsky.social &co identify a horizontally acquired genetic island encoding peptides that drive #autolysis & human cell lysis, aiding colonization & disease 🧪 @plosbiology.org plos.io/4aP2om9

Top: Organisation of the nap island in Neisseria gonorrhoeae FA1090. Grey arrows, flanking genes (NEIS0808, pseudouridine synthase; NEIS0794, histidyl-tRNA synthase); blue arrows, genes coding for GG-containing peptides; orange arrows, genes predicted to be involved in peptide processing and secretion; green arrow, gene of unknown function; pink boxes, Correia elements. Bottom: Transmission electron microscopy images from bacteria in HEPES (T = 75 min). Some wild-type bacteria appear normal (indicated with arrow numbered 1), with many others having a dense (arrow 2) or very dense (arrow 3) cytoplasm, periplasmic expansions (arrow 4), or appearing as ghost cells (arrow 5). Extracellular vesicles (arrow 6) and released cellular content (arrow 7) are also visible. Periplasmic expansions are not observable in the ΔltgA or ΔnapRABC strains. Cytoplasm condensation appears more homogenous in the ΔltgA mutant.

Programmed cell death distinguishes N. gonorrhoeae & N. meningitidis from other #Neisseria species. @katyponcin.bsky.social &co identify a horizontally acquired genetic island encoding peptides that drive #autolysis & human cell lysis, aiding colonization & disease 🧪 @plosbiology.org plos.io/4aP2om9

Top: Organisation of the nap island in Neisseria gonorrhoeae FA1090. Grey arrows, flanking genes (NEIS0808, pseudouridine synthase; NEIS0794, histidyl-tRNA synthase); blue arrows, genes coding for GG-containing peptides; orange arrows, genes predicted to be involved in peptide processing and secretion; green arrow, gene of unknown function; pink boxes, Correia elements. Bottom: Transmission electron microscopy images from bacteria in HEPES (T = 75 min). Some wild-type bacteria appear normal (indicated with arrow numbered 1), with many others having a dense (arrow 2) or very dense (arrow 3) cytoplasm, periplasmic expansions (arrow 4), or appearing as ghost cells (arrow 5). Extracellular vesicles (arrow 6) and released cellular content (arrow 7) are also visible. Periplasmic expansions are not observable in the ΔltgA or ΔnapRABC strains. Cytoplasm condensation appears more homogenous in the ΔltgA mutant.

Programmed cell death distinguishes N. gonorrhoeae & N. meningitidis from other #Neisseria species. @katyponcin.bsky.social &co identify a horizontally acquired genetic island encoding peptides that drive #autolysis & human cell lysis, aiding colonization & disease 🧪 @plosbiology.org plos.io/4aP2om9

Luckily for us yeast can’t help them and want to party like it’s the best rave of the century ! Gives a new meaning to the word “wild” in wild fermentation! Credit Skeletons Claw for graphics. #yeast #cider #autolysis #WildFermentation