Mid-week check-in 🧠 How’s your brain today?
Unwind with Retro Brands—50 relaxing puzzles for a calm, focused break.
Share a small win or gratitude moment 💬
➡️ Link in bio
#BrainSky #WellnessWednesday #MentalAgility #WordSearch #PuzzleLover
Introducing the next generation of brain research!
Get to know the 14 brilliant researchers who were awarded American Brain Foundation Next Generation Research Grants in 2026 and learn more about their groundbreaking work! 🧠 🔬 #BrainResearch #BrainSky
“The reality of neuroplasticity is far messier: it’s a biological process that is incremental and frustratingly slow.” Exploring neuroplasticity as metaphor, from @Aeon.co. #BrainSky buff.ly/HoCtU29
Most diagnostic errors aren’t knowledge gaps. They’re framing errors.
Launching a 5-part series on cognitive bias in neurohospitalist consults.
First up: Occam’s Razor Bias. When does parsimony mislead?
#Neurohospitalist #ClinicalReasoning #NeuroSky #BrainSky #MedSky
Wishing a happy 68th birthday to neuroscientist Brigitte Kieffer, who in 1992 published a landmark paper on the genetics of the delta opioid receptor, giving the world a powerful new way to study the mechanisms of addiction.
#WomenInSTEM #NeuroSky #BrainSky #BookSky 🧪🧠
🧠 Yesterday was #WorldEncephalitisDay, but awareness never stops. Early detection saves lives.
See how teams identified rare HHV-6 encephalitis in a transplant patient, because vigilance always matters. 📖 doi.org/10.1097/IM9....
#AcadeMax #ZJU #Science #MedSky #BrainSky #AcademicSky
Research Discovery: Alzheimer’s disease disrupts the brain’s internal clock, causing patients to lose track of day and night before they lose memories.
Diseases Affected: Alzheimer’s disease
Key Findings: Alzheimer's disease disrupts the brain’s natural circadian cycle, which not only cause confusion about day and night for the people, but also for their brain’s support cells, which prevents them from clearing out harmful amyloid protein buildups, which destroy neurons.
What’s Next? Researchers believe that this finding could set the stage for a new type of therapy to restore or stabilize the brain’s internal rhythm and slow disease progression.
Solstices can mess with our sense of night and day, but so can #Alzheimers disease. According to the Alzheimer’s Research Foundation, researchers at Washington University found that the disease disrupts the brain’s internal clock. #Brainsky #WinterSolstice
Research Discovery: The common insecticide chlorpyrifos (CFP) causes brain damage, leading to poor motor skills in children and adolescents.
Key Findings: Researchers determined that prenatal exposure to CFP causes structural and functional brain damage among children in New York City, with severity in direct proportion to the level of exposure. Affected children performed poorly on tests to measure motor speed and coordination.
“Current widespread exposures, at levels comparable to those experienced in this sample, continue to place farm workers, pregnant women, and unborn children in harm’s way. It is vitally important that we continue to monitor the levels of exposure in potentially vulnerable populations, especially in pregnant women in agricultural communities, as their infants continue to be at risk”, said Virginia Rauh, ScD, Columbia Mailman School.
What’s Next? This research shows exactly how prenatal CFP exposure damages the brain. Reinstating the ban on its use in agricultural applications could likely protect people from these severe effects.
Researchers at Columbia University’s Mailman School of Public Health have discovered how prenatal exposure to the #insecticide #chlorpyrifos (CPF) has lasting effects on the brain, reduce motor skills in children and adolescents. #Brainsky #PublicHealth
A new systemic analysis published in HAMA Neurology has found one in two people in the United States is affected by a neurological disease or disorder.
@aanmember.bsky.social reports new findings that 54% of people in the United States (more than 180 million) are affected by a neurological disorder. This analysis underscores the urgent need for increased funding for #BrainResearch. #Brainsky #Migraine #Neuropathy
Research Discovery: Older adults can delay cognitive decline from Alzheimer’s disease with just a modest amount of physical activity.
Diseases Affected: Alzheimer's Disease
Key Findings: Adults with elevated levels of amyloid-beta proteins (a precursor to Alzheimer’s) can delay cognitive decline by three years just by taking 3,000 steps per day. And they can delay this decline by seven years by taking 5,000 to 7,500 steps per day.
What's Next? The researchers plan to explore which types of physical activity might be most important, and the biological mechanisms linking physical activity, tau protein buildup, and cognitive health.
We’re excited to share that a new study by THREE past ABF Next Generation Research Grant recipients shows that older adults can slow the onset of #Alzheimers symptoms just by taking 3,000 steps per day! Congrats, Drs. Yau, Chhatwal, and Sperling! #Brainsky
Research discovery: Certain cells in the brainstem are responsible for transmitting signals of chronic pain. They could potentially serve as biomarkers for chronic pain or even an “off switch.”
Diseases affected: chronic pain
Researchers at @upenn.edu have identified that Y1 receptor-expressing #neurons in the brainstem’s lateral parabrachial nucleus are associated with #chronicpain. This suggests possibilities for future biomarkers and treatments. #Brainsky
This week’s blog recaps last month’s Meet the Researchers webinar, which featured seven of this year’s Next Generation Research Grant recipients. The full #webinar is now archived on our YouTube channel. Read about the remarkable work they’re doing buff.ly/9pocjIo ⬇️ #BrainResearch #BrainSky
Spotlight on Dr. James Greene, @emoryuniversity.bsky.social neurohospitalist and founding director of Emory’s multi-hospital program, a longtime NHS leader helping shape the field.
Join us in Denver for #NHS2025 🧠
🔗 neurohospitalistsociety.member365.com/public/event...
#NeuroSky #MedEd #BrainSky
What is the Critical Brain Hypothesis? Increasingly, researchers are considering that the brain processes signals in a way that incorporates a delicate balance between order and chaos.
So brain signals are random? No, not exactly. This hypothesis suggests that brain signals travel from neuron to neuron in chain reactions that incorporate mass complexity but also flexibility.
Can you help me picture that? Think of forest fires and how they grow as flames spread out to trees that happen to be nearby. This behavior is mathematically predictable, but increasingly complex as the fire adapts to the various conditions in the moment.
Why would the brain work like that? By operating at the edge between order and disorder, the brain is maximizing its network of neurons for complex thinking, but it’s also allowing for flexibility to adapt to new signals in the moment. If the brain operates like a forest fire, being on the edge of chaos helps to keep it under control.
@newscientist.com discusses the #CriticalBrainHypothesis, a concept proposing that the brain manages enormous complexity by operating at the tipping point between order and disorder. This has profound implications for brain disease research. #Brainsky
Don't miss tonight's free webinar! Next Generation Research Grants launch long-term research careers through funding innovative projects by early-career investigators. Join us to meet the researchers and hear how their finding will lead to new preventions, treatments, and cures across the full spectrum of brain diseases and disorders. The webinar will be held Monday, September 22 at 7 PM Central Time.
Tonight, at 7 p.m. Central, tune into a free webinar to meet Next Generation Researchers about their projects to study brain diseases. 💻 Register now to watch live and hear how their findings will lead to new preventions, treatments, and cures: buff.ly/da5LjYM #BrainSky #BrainHealth
The Neurohospitalist Society is a professional home for inpatient neurology.
🧠 Advance care. Empower neurohospitalists. Build community.
Students, residents, APPs, MDs, NHS is for you.
Tag a future neurohospitalist!
#NeuroSky #Neurology #MedSky #BrainSky
Hormone replacement therapy might protect a woman’s brain against #Alzheimer’s disease, but only if the timing’s right, new research says. #Medsky #healthsky #brainsky #brainhealth #health #healthnews
www.healthday.com/health-news/...
Researcher feature: Sophie Rengarajan, MD, PhD, 2025 Next Generation Grantee in neuromuscular disease. Dr. Rengarajan is studying Duchenne Muscular Dystrophy (DMD). DMD weakens muscles due to a genetic defect. Dr. Rengarajan is investigating how cell interactions contribute to DMD and how affected cells respond to gene therapy. Her findings could improve treatment and reduce side effects of gene therapy.
Meet 2025 Next Generation Research Grant recipient Sophie Rengarajan, MD, PhD, of UCLA Medical Center. Dr. Rengarajan is studying gene-expression changes in Duchenne #MuscularDystrophy (#DMD). Funded with the Neuromuscular Study Group and @aanmember.bsky.social. 🧠🔬 More: buff.ly/IFon3kD #BrainSky
Researcher Feature: Deborah Rose, MD. 2025 Next Generation Research Grantee studying cognitive aging and age-related memory loss. Dr. Rose is exploring how adverse childhood experiences (ACEs) affect brain health later in life, particularly among diverse populations. Dr. Rose will study links between ACEs, stress-related brain changes, and cognitive decline.
Meet 2025 Next Generation Research Grantee Deborah Rose, MD. She is studying how adverse childhood experiences influence #neurodegeneration in marginalized racial and ethnic groups. Funded with the McKnight Brain Research Foundation and @aanmember.bsky.social. #Brainsky 🧠 Learn more buff.ly/zTCSg3O
Research Discovery: An experimental drug called ipilimumab appears able to harness the immune system to fight and remove brain cancer.
Diseases Affected: Glioblastoma
Key Findings: Two years and eight months after starting to take ipilimumab, glioblastoma patient Ben Trotman’s scans show no signs of tumor.
What's next? The NHS is launching further trials of ipilimumab.
Ben Trotman was diagnosed with #glioblastoma in October 2022. Now, more than two years after starting an experimental immunotherapy drug called ipilimumab, he has no signs of cancer. More trials are underway to further test and validate ipilimumab. #BrainSky
New report! Cure One, Cure Many Award: Improving Diagnosis for Lewy Body Dementia (LBD).
With the @alzassociation.bsky.social, The Michael J. Fox Foundation, and@aanmember.bsky.social, we funded research to accelerate progress in the diagnosis of #LewyBodyDementia (LBD) through a $3M grant awarded in 2022. #BrainSky
🔬 Read the full report ➡️ buff.ly/u6E0kYN
Life without brain disease is possible. But finding cures depends on research, and research depends on support from donors like you. Thank you for joining us in this important work. #BrainSky
It's #WorldBrainDay, a day to promote awareness about brain health and neurological disorders.
It also made me think of this #wine label.
#Winesky #Brainsky #winepairing
Meet 2025 Next Generation Research Grant recipient Tiffany Li, PhD. She will work with cancer patients to establish new biomarkers for chemotherapy-induced peripheral neuropathy (#CIPN). Funded with @foundationforpn.bsky.social. #BrainSky 🧠 Read more about Dr. Li's research: buff.ly/GsrzpXX
Neuroplasticity is your brain’s power to rewire itself.
Want to upskill faster?
• Practice deep focus (ditch the distractions)
• Learn in short, spaced sessions
• Teach what you just learned
• Sleep like it’s your job
• Challenge old habits with new tasks
#BrainSky #LearnSky #SkillSky
One of the mainstays of the approach to this research is that we build community capacity such that when the research component of the project is complete, the community or the community members are better off, says Lesli Skolarus, MD
What gives me hope is that where there is great need, people want to address that need. We still have a long way to go in terms of stroke treatments and stroke prevention. Stroke is such a highly prevalent disease with consequences not only for the person who had a stroke, but for their families and communities as well, says Lesli Skolarus, MD.
![I applied for [the Next Generation Research Grant] when I had just started stroke fellowship, and it really did change my career. It gave me two really important things. It allowed me to get a master's degree in healthcare research, increasing the rigor of my science. And it protected my time to launch my career and to really think about where I could have the biggest impact, not on a patient-by-patient basis, but on a community or societal level, says Lesli Skolarus, MD.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:njtn4pwvg3c76pwserqqgily/bafkreiaxnmjetuujwtrahyhrefatdxanmd76vtopojeia7347y7gqtqr4i)
I applied for [the Next Generation Research Grant] when I had just started stroke fellowship, and it really did change my career. It gave me two really important things. It allowed me to get a master's degree in healthcare research, increasing the rigor of my science. And it protected my time to launch my career and to really think about where I could have the biggest impact, not on a patient-by-patient basis, but on a community or societal level, says Lesli Skolarus, MD.
Lesli E. Skolarus, MD, MS, is a professor of neurology at Northwestern Feinberg. She spoke with us about using community engagement approaches to prevent stroke, her reasons for hope in this field, and the impact of receiving a Foundation grant early in her career. #BrainSky
As we age, maintaining cognitive health is important. Julie Suhr, Director of Clinical Training at the Ohio Musculoskeletal and Neurological Institute, shares five essential habits to help you keep your mind sharp and reduce your risk of cognitive decline. #HealthyAging #BrainSky
Post-traumatic stress disorder (#PTSD) has been added to our A to Z page on the website. This disorder can develop after an extremely distressing event, leading to persisting nightmares, anxiety, flashbacks, impaired sleeping, and more. #BrainSky
📰 Read more about PTSD buff.ly/jloilHZ%E2%A...
Research Discovery: The FDA has approved a new drug, Imaavy, to treat generalized myasthenia gravis (gMG).
Diseases Affected: Generalized Myasthenia Gravis (gMG)
Key Findings: Patients with gMG produce antibodies that attack their own cells. This autoimmune disease is made worse by a protein called FcRn, which helps antibodies survive longer. Normally that’s a good thing, but for people with gMG, those antibodies are harmful. Imaavy works by blocking production of the protein FcRn.
What’s Next: Imaavy’s approval means that it can be administered to adults and teens aged 12 years and up who have tested positive for anti-acetylcholine receptor or anti-muscle-specific kinase antibodies.
@Medscape.com reports Imaavy is approved for treating generalized myasthenia gravis (gMG). Imaavy blocks production of the protein FcRn. Clinical trials showed significantly reduced symptoms; results maintained after a 20-month follow-up. #MyastheniaGravis #MyastheniaGravisAwarenessMonth #BrainSky
This stunning #MicroscopyMonday is an adult fly #brain, labeled in orange is the mushroom body, the memory center in flies, and the neurons on the sides are part of the medulla of the eye, essential for color vision. (Si Lab) 🧠 #neurosky #brainsky #scisky
