Transplantations de reins, de cœur ou de foie de porcs à des patients : «On est en train de se dire que ça devient possible» Alors qu’en France des centaines de malades en attente d’organes meurent chaque année, la recherche sur les xénogreffes s’accélère aux Etats-Unis et en Chine. Dans cette odyssée médicale, un laboratoi...

#Xénogreffes : avancées rapides (reins de porc modifiés, survie record) face à la pénurie d’organes.
👉La recherche, dopée par #CRISPRCas9, soutenue par l'@inserm.fr, nourrit l’espoir… malgré enjeux éthiques et retard français.
www.liberation.fr/societe/sant...

We previously engineered Saccharomyces cerevisiae through CRISPR-Cas9 integration to produce Ply511, a bacteriophage endolysin active against L. monocytogenes, showing the potential of engineered yeast to produce endolysins for biocontrol. In this study, we extended this approach to the probiotic yeast S. boulardii and directly compared the two yeasts as secretion hosts for Ply511. Using a simulated human gastrointestinal environment, we evaluated their ability to retain endolysin activity and reduce L. monocytogenes levels.

New paper from the CEB- @uminho.bsky.social & APC
𝐄𝐯𝐚𝐥𝐮𝐚𝐭𝐢𝐨𝐧 𝐨𝐟 𝐭𝐡𝐞 𝐝𝐞𝐥𝐢𝐯𝐞𝐫𝐲 𝐨𝐟 𝐚𝐧 𝐚𝐧𝐭𝐢-𝐋𝐢𝐬𝐭𝐞𝐫𝐢𝐚 𝐞𝐧𝐝𝐨𝐥𝐲𝐬𝐢𝐧 𝐯𝐢𝐚 𝐂𝐑𝐈𝐒𝐏𝐑-𝐂𝐚𝐬𝟗 𝐞𝐧𝐠𝐢𝐧𝐞𝐞𝐫𝐞𝐝 𝐩𝐫𝐨𝐛𝐢𝐨𝐭𝐢𝐜 𝑺𝒂𝒄𝒄𝒉𝒂𝒓𝒐𝒎𝒚𝒄𝒆𝒔 𝒃𝒐𝒖𝒍𝒂𝒓𝒅𝒊𝒊
Appl Microbiol Biotechnol buff.ly/pDDfR3f
#CRISPRCas9
@ellen-murr.bsky.social @rioscolombo.bsky.social @colinhillucc.bsky.social

CBS News | Breaking news, top stories & today's latest headlines CBS News offers breaking news coverage of today's top headlines. Stay informed on the biggest new stories with our balanced, trustworthy reporting.

After a baby became the world's first CRISPR gene editing therapy patient, CHOP wants to expand treatment to others www.cbsnews.com
#crispr #crisprcas9 #dna #Geneticengineering #genome #stem #medical #health #artificalintelligence #ai #medicalstudent

First we build the tools,
then they build us.
-Marshall McLuhan
#crispr #crisprcas9
#dna #cloning #geneticengineering #gentics #medical #health
#Artificalintelligence #medicalstudents

The Chemistry of Genome Editing:
cen.acs.org
#crispr #crisprcas9
#dna #cloning #geneticengineering #gentics #medical #health
#Artificalintelligence #medicalstudents

Nouveaux OGM : les gros semenciers prêts à privatiser le vivant en Europe Alors que l'Union européenne est d'accord pour dérèglementer les nouvelles techniques génomiques (NGT), les grandes firmes de semences multiplient les demandes de brevets. Un pas de plus vers la priva...

Nouveaux #OGM : les gros semenciers prêts à privatiser le vivant en #Europe

reporterre.net/Nouveaux-OGM...

#NGT #OEB #Corteva #WWS #Bayer #Monsanto #Syngenta #ChemChina #BASF #CrisprCas9 #Berkeley #agroTERRORISME

🧬 CRISPR technology revolutionizes gene editing 🔬, enabling precise DNA modification for research, diagnostics, and future medical innovations 🚀.
#CRISPR #CRISPRCas9 #GeneEditing #Biotechnology #MolecularBiology #GeneticEngineering #LifeScienceStudents #ResearchInnovation #Bioinformatics #BioResire

Boersma wil bovendien grote zaadbedrijven vrij spel geven door deregulering
van #NGTs (nieuwe genomische technieken) zoals #CRISPRCas9 met alle ellende van dien voor kleine veredelaars die daardoor dure rechtszaken vrezen. 6/

This review explores how #CRISPRCas9, #epigenetic modulation, somatic cell genome editing, and #RNAbasedtherapies are transforming disease prevention by enabling precise control of #genes, while addressing their technical challenges.

#OpenAccess: doi.org/10.1016/j.ge...

#CellEDIT #CRISPR #GeneEditing #Biotech #FluidFM #ScienceLife #GenomeEngineering #CellLineEngineering #LifeSciences #DrugDiscovery #Pharma #SingleCell #CRISPRCas9 #Cytosurge #Research

Svolta Senza Precedenti nella Biologia Sintetica Trasferimento Intatto di Interi Cromosomi Umani, rappresenta una Svolta Senza Precedenti nella Biologia Sintetica. Un risultato scientifico di portata straordin

Trasferimento Intatto di Interi Cromosomi Umani, rappresenta una Svolta Senza Precedenti nella Biologia Sintetica. #biologiasintetica #CrisprCas9 #cromosomiumani #telomeri #trapiantocromosomico #UniUD #UniversitàdiUdine
scienzamagia.eu/medicina-e-b...

#CellEDIT Winter Sale ❄️
Vector-free, intra-nuclear CRISPR editing for hard-to-transfect cell lines — with guaranteed monoclonality.
Check feasibility & pricing via the CellEDIT Quoter. 👉 www.cytosurge.com/celledit-win...
#GeneEditing #CRISPR #CRISPRCas9 #GenomeEngineering #GeneticModification

This review highlights #CRISPRCas9 as a precise #GeneEditing tool with therapeutic applications across #cancers, and acquired diseases, discussing #ClinicalTrials, off‑target challenges, and advances in #viral and #NonViralDelivery systems.

#OpenAccess: doi.org/10.1016/j.ge...

Black Friday Week for #CellEDIT 🖤 Order 2 custom CRISPR cell lines, get 1 FREE (3 for 2).

To redeem, connect with our Dr. Gorka Santos by Dec. 1, 11:59 PM PST 👉 https://bit.ly/43MKm13

#BlackFriday #BlackFridayWeek 🛒💸💰#GeneEditing #CRISPR #CRISPRCas9 #GenomeEngineering #GeneticModificatio

Original post on libera.site

Z toho se někteří opupínkují, ale já bych do toho hned šel. 😁
15 lidí s velmi vysokými hodnotami špatného cholesterolu podstoupilo dvouhodinovou infuzi s genovou terapií na vypnutí genu ANGPTL3. Potom měli i po měsících o 50% nižší cholesterol.

#^ […]

Remarkable, groundbreaking progress for cardiometabolic science and medicine!!! #FGF21R #GLP1 #APOC3 #ANGPTL3 #PCSK9 #mAb #siRNA #ASO #CRISPRCas9
Shoutout to ♥️ basic and clinical scientists moving this forward for our patients! @ahascience.bsky.social #AHA25 #PrevCards #Lipidology

Janet Rossant, the Gairdner Foundation President & Scientific Director, met with Jennifer Doudna, 2016 Canada Gairdner International Award laureate and 2020 Nobel laureate, during Dr. Doudna’s visit to Toronto for the Oliver Smithies Lecture.

#GairdnerAwards #CRISPRCas9

To obowiązkowa lektura, jeśli chcesz zrozumieć, dlaczego CRISPR nazywa się największym przełomem w biologii od odkrycia struktury DNA. Uczy nie tylko o genach, ale też o tym, jak nauka i etyka ścierają się w świecie, w którym coraz śmielej ingerujemy w ewolucję. #genetyka #CRISPRCas9

Santé. Trisomie 21 : des chercheurs parviennent à retirer le chromosome en trop Des chercheurs japonais ont eu recours à une technique novatrice pour traiter, in vitro, le syndrome de Down (trisomie 21). Avec des « ciseaux ...

🧬 Des chercheurs japonais ont réussi à retirer le 3e #chromosome21 dans des cellules grâce à #CRISPRCas9.
👉 Expression génétique restaurée
⚠️ Non applicable chez l’humain, mais ouvre des pistes de recherche.
🔎 Soulève des enjeux éthiques

www.leprogres.fr/magazine-san...

Immaginiamo il DNA come una gigantesca enciclopedia che contiene tutte le istruzioni per costruire e far funzionare un essere vivente, dalla più piccola pianta al corpo umano. #CrisprCas9 #cromosoma #DNAumano #editinggegnoma #ingegneriacromosomica #malattiegenetiche
scienzamagia.eu/scienza-tecn...

A Single Genetic Tweak Stops Mosquitoes from Spreading Malaria Mosquitoes engineered to swap out an amino acid in a key protein were resistant to malaria infection, preventing them from transmitting the disease.

Neue Strategie gegen #Malaria: Mithilfe von #CRISPRCas9 haben Forscher:innen eine einzelne Aminosäure in Mücken genetisch so verändert, dass sie keine Malaria-Erreger mehr auf Menschen übertragen können. Wie genau das funktioniert, erklärt #TheScientist. www.the-scientist.com/a-single-gen...

5/ 💬Let’s talk about your challenge in cell line engineering!

#GeneEditing #CRISPR #CRISPRCas9 #GenomeEngineering #GeneticModification #PrecisionGeneEditing #FunctionalGenomics #GeneTherapy #SingleCellEngineering #NextGenGeneEditing #CellEngineering #GeneticallyEngineeredCells #SyntheticBiology

Babies’ Babbling Offers Insight Into Cognitive Ability at Age 30 and Beyond | Newswise Babies’ babbling offers insight into cognitive ability at age 30 and beyond

Babies’ Babbling Offers Insight Into Cognitive Ability at Age 30 and Beyond
www.newswise.com/articles/bab...
#cognitiveaging #cognitiveability #genetics #cognition #neuroscience
#colorectalcancerawareness #ColorectalCancer #Irinotecan #CRISPRCas9 #geneediting #topoisomerase #Selinexor

CRISPR used to remove extra chromosomes in Down syndrome and restore cell function Japanese researchers have successfully eliminated the extra chromosome responsible for Down syndrome using CRISPR gene editing.

Very Interesting news to the scientific community! Curious to see where this types of progress leads to #CRISPR #CRISPRCas9 #ScienceNews #Science #earthcom

Clinical applications of the CRISPR/Cas9 genome-editing system

Must-read review! Most downloaded article!

This review discusses the current status of #clinicaltrials involving #CRISPRCas9 in various illnesses and analyzes the use of #transfection vehicles for CRISPR/Cas9, including viral and non-viral vectors. #medsky

#OpenAccess: buff.ly/kApYbge

Efficient mRNA delivery to resting T cells to reverse HIV latency - Nature Communications Resting T cells are difficult to manipulate, and are a reservoir for latent HIV. Here, the authors develop a lipid nanoparticle formulation with the ability to transfect resting primary human T cells,...

Efficient mRNA delivery to resting T cells to reverse HIV latency

Two methods , one uses #CRISPRCas9

www.nature.com/articles/s41...

FluidFM® CellEDIT Service - Form Contact us | Cytosurge

📩 Drop a DM or reach out to us via our contact form to discuss your project: www.cytosurge.com/solutions/se...

#GeneEditing #CRISPRCas9 #PrecisionGeneEditing #GeneTherapy #PrecisionCRISPR #CellEngineering #CustomCellLines #CellLine #CellManipulation #SyntheticBiology #SingleCell

This review article describes the structure and mechanism of the #CRISPRCas9 system, summarizes its #geneediting technology, and discusses its clinical applications in various #nervoussystem diseases. #mutation #medsky

#OpenAccess: www.sciencedirect.com/science/arti...

Fred Hutch study finds genetic driver of drug resistance in small cell lung cancer A study of human tumor cells implanted in mice from the MacPherson Lab at Fred Hutch describes a new way to screen for the genes that matter in chemotherapy resistance in small cell lung cancer.

In work published in Science Advances, researchers in the @davidmacphersonlab.bsky.social used #CRISPRCas9 on #SCLC tumor cells to better model how tumors that initially respond to chemotherapy become resistant. www.fredhutch.org/en/news/cent...