[Significance of CYP2D6 oxidation genotype as a risk factor in development of allergic diseases] - PubMed The relationship between genetically determined polymorphic metabolism and susceptibility to allergic diseases has aroused much interest. The aim of our study was to evaluate whether patients with all...

old but interesting; abstract only:

Significance of CYP2D6 oxidation genotype as a risk factor in development of allergic diseases [2003]

pubmed.ncbi.nlm.nih.gov/12879776/

#allergies #immunology #genetics #CYP2D6 #asthma

1/1 Did you know that the #PharmVar 'Allele Details' page now shows Activity Values for #CYP2D6, #CYP2C9 and #DPYD in addition to CPIC function and also provides links to easily look up allele frequencies?

I'm very impressed by the thorough work @holtjma.bsky.social, @meberle.bsky.social and team have done in building #StarPhase - it really checks all the boxes for reliable calling of #pharmacogenomic star alleles, even for #CYP2D6! 🙌

Case report: metoclopramide induced acute dystonic reaction in adolescent CYP2D6 poor metabolizers Metoclopramide is indicated for the management of gastroesophageal reflux, gastric stasis, nausea, and vomiting. Metoclopramide-induced acute dystonic reactions (MIADRs), along with repetitive involun...

Case report: metoclopramide induced acute dystonic reaction in adolescent CYP2D6 poor metabolizers [2023]
pmc.ncbi.nlm.nih.gov/articles/PMC...
#metoclopramide #Reglan #CYP2D6 #pharmacogenetics #pharamcogenomics #DrugMetabolism #pharmacology #gastroenterology #dopamine #AdverseReactions #SideEffects

Tramadol intoxication in children: An emerging issue Tramadol intoxication in children: An emerging issue

Pharmacogenetics
Tramadol intoxication in children: An emerging issue
www.em-consulte.com/article/1670...
#Tramadol #Children #Overdose #CYP2D6 #Pharmacogenetics