📢New Advance Article: Interested in a #CellFree protocol for subunit-specific protein labelling? Researchers at CNRS Biologie present a new protocol for producing deuterated or methyl-labelled complexes using cell-free technology.
➡️Read the full story: doi.org/10.1039/D5CB...

Not all #cellfree expression kits are created equal, but #myTXTL delivers what matters most:
✅ High yield (>1 mg/mL)
✅ Toxic protein expression
✅ Single-day workflows
✅ Proven in peer-reviewed publications
For results you can count on, choose myTXTL.
👉 arborbiosci.com/products/cel...

💡 We built a quantitative human-based cell-free translation platform that tests thousands of reactions in parallel, directly measuring protein synthesis while bypassing cellular toxicity.

#quantitativebiology #RNA #ribosome #cellfree #drugdiscovery

From biosensors to bioproduction — 2025 has been a big year for myTXTL.
Researchers around the world are using our cell-free system to:
✅ Accelerate gene editing research
✅ Build next-gen biosensors
✅ Enable greener, faster biomanufacturing

#CellFree #SyntheticBiology #ProteinExpression #myTXTL

Why wait weeks for cloning + purification when you can run assays tomorrow? ⏱️
Get activity-ready protein in a single day with #myTXTL, just add DNA.
Less pipetting. More results. 👉 arborbiosci.com/products/cel...
#ProteinExpression #SynBio #SyntheticBiology #CellFree

⚡ Same-day protein expression.

With myTXTL cell-free kits, skip cloning, lysis & purification – go straight to results.

High yield. Activity-ready. Fast.

👉 arborbiosci.com/products/cel...
#ProteinExpression #SynBio #CellFree #myTXTL

Hello World !!
The Maerkl Lab is now on Bluesky...

#syntheticbiology #cellfree #microfluidics #transcriptinalregulation

Design, Assemble and Express with Confidence: Enabling High-throughput DNA Assembly and Protein Expression Workflows Cell-free protein synthesis (CFPS) can permit workflow time savings and high throughput, while avoiding several limitations associated with in vivo protein expression systems. Learn more about how you...

#Cellfree #proteinsynthesis workflows avoid several limitations associated with in vivo protein expression systems. With the right design tools, #CFPS workflows can take you from design to protein purification, save time & increase throughput. Learn more in our blog: https://nebiolabs.com/4lIf6Hd

Our latest research has just been published. Our methodology enables the rapid selection of the most effective antimicrobial peptide combinations to fight resistant pathogens.
#bacteriocins #SyntheticBiology #CellFree #AntimicrobialResistance #AMR #Biotechnology #Microbiology #InnovationInBiotech

Big congrats to Greg, the first author, for getting this work ready for preprint. It's extra special because today is the lab's 2 year birthday! 🥳 #newpi #xenopus #frogwranglers #cellfree

New on @biorxiv!!!!!!
We’re excited to share our latest paper on combining cell-free systems and machine learning to express full genome in vitro.

Check it out now! 👉 www.biorxiv.org/content/10.1...

Catch us at SEED in Houston this June to discuss this work.
#CellFree

Genomic and fragmentomic landscapes of cell-free DNA for early cancer detection - Nature Reviews Cancer In this Review, Bruhm et al. provide a comprehensive overview of targeted and genome-wide cell-free DNA detection approaches, examining their potential to complement existing screening programmes or enhance early cancer detection for those cancers without effective screening methods.

#Review 🚨

In the May issue of #NRC, Bruhm et al. provide a comprehensive overview of targeted and genome-wide #cellfree DNA (cfDNA) detection approaches.

Check it out 👇

Classified: A Cell-Free DNA Cancer Signature Ensemble Classifier A team led by Francesca Demichelis and Misha Beltran reports the development of the NEMO, which assesses DNA methylation at selected regions in cell-free DNA from liquid biopsies to provide a non-inva...

[NEW #Blog] Some classified information is OK to share. Our latest blog looks at #cellfree #DNA Cancer Signatures - an emsemble classifier and non-invasive tool for cancer monitoring 🩸 bit.ly/4bkKoAC

#AACR2025 #AACR25 #CancerResearch #KRAS

Cell-free protein synthesis platforms for accelerating drug discovery Cell-free protein synthesis is a platform for streamlined production of macromolecules. Recently, several proteins with pharmaceutical relevance were …

Pleased to share my latest review on Cell-Free Protein Synthesis #CFPS and #AI/ML for accelerating drug discovery

www.sciencedirect.com/science/arti...

#CellFree #SynBio

Application Note: Accelerated CRISPR-Cas Characterization with ENFINIA Linear DNA Templates and Cell-Free TXTL - ElegenBio

Explore Elegen's latest app note on #CRISPR-Cas systems! It highlights #myTXTL's potential in expressing the CRISPR-Cas operon with Elegen's linear DNA templates, enabling simultaneous expression of multiple enzymes. elegenbio.com/resources/li...
#cellfree #EnfiniaDNA #genesynthesis

Cell-free protein synthesis for biocatalysis Cell-free protein synthesis (CFPS) serves as an innovation booster in the field of biocatalysis. By integrating CFPS into the design and development o…

Cell-free protein synthesis for biocatalysis

Read this new overview on the flexibility of #CFPS systems for rapid protein prototyping

www.sciencedirect.com/science/arti...

#CellFree #SynBio

Makes you want to go back to using a landline.
No tracking anyone by landline. 😎🤷‍♀️
#CellFree ☎️

Beyond In Vivo, Pharmaceutical Molecule Production in Cell-Free Systems and the Use of Noncanonical Amino Acids Therein Throughout history, we have looked to nature to discover and copy pharmaceutical solutions to prevent and heal diseases. Due to the advances in metabolic engineering and the production of pharmaceutical proteins in different host cells, we have moved from mimicking nature to the delicate engineering of cells and proteins. We can now produce novel drug molecules, which are fusions of small chemical drugs and proteins. Currently we are at the brink of yet another step to venture beyond nature’s border with the use of unnatural amino acids and manufacturing without the use of living cells using cell-free systems. In this review, we summarize the progress and limitations of the last decades in the development of pharmaceutical protein development, production in cells, and cell-free systems. We also discuss possible future directions of the field.

New #publication is online in Chemical Reviews! Super stoked about our collaboration and explore #biotechnology #phamaceutical development, #unnatural amino acids, #cellfree and #bioconjugation. Enjoy!

pubs.acs.org/doi/10.1021/...

Cell-Free PURE System: Evolution and Achievements The cell-free protein synthesis (CFPS) system, as a technical core of synthetic biology, can simulate the transcription and translation process in an …

Cell-Free PURE System: Evolution and Achievements

www.sciencedirect.com/science/arti...

#CellFree #CFPS #SynBio

Autonomous ribosome biogenesis in vitro - Nature Communications The realization of ribosome biogenesis in vitro is recognized as a critical milestone in the creation of artificial cells. Here, the authors developed a method to detect newly synthesized ribosomes, w...

Autonomous ribosome biogenesis in vitro
www.nature.com/articles/s41...

#CellFree #SynBio

Cell-Free Gene Expression: Methods and Applications Cell-free gene expression (CFE) systems empower synthetic biologists to build biological molecules and processes outside of living intact cells. The foundational principle is that precise, complex bio...

If you are interested in Cell-Free Protein Synthesis, you can't miss this new comprehensive review:

pubs.acs.org/doi/full/10....

#CellFree #CFPS #SynBio

The effects of solubility tags and their removal (detagging) with 3C protease on cell-free protein expression The ability to evaluate the effect of different solubility tags on protein expression and the impact of their removal can be done simultaneously on eProtein Discovery. Data in this application note va...

With a start-up, we developed Cell-Free Protein Synthesis reagents for their digital microfluidics platform to modulate disulfide bridge formation, and activity and remove solubility tags for enhanced yields

🔵 www.nuclera.com/resource-lib...

🔵 www.nuclera.com/resource-lib...

#CellFree #CFPS

The future of cell-free synthetic biology Cell-free synthetic biology aims at the targeted replication, design, and modification of life processes in open systems by breaking free of constrain…

My point of view on the future of Cell-Free Synthetic Biology www.sciencedirect.com/science/arti...

#CellFree #SynBio

🦋 Stemloop is now on Bluesky!

We build biosensors to measure small molecules using #CellFree #SynBio #RNA and #GeneticCircuits.

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